Sensitive detection of gallic acid in food by electrochemical sensor fabricated by integrating nanochannel film with nanocarbon nanocomposite DOI Creative Commons
Jiasheng Li,

Jiahui Lin,

Tao Luo

et al.

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: Nov. 12, 2024

Sensitive detection of gallic acid (GA) in foods is great significance for assessing the antioxidant properties products and ensuring consumer health. In this work, a simple electrochemical sensor was conveniently fabricated by integrating vertically-ordered mesoporous silica film (VMSF) with electrochemically reduced graphene oxide (ErGO) nitrogen quantum dots (NGQDs) nanocomposite, enabling sensitive GA food sample. A water-soluble mixture (GO) NGQDs drop-cast onto common carbon electrode, glassy electrode (GCE), followed rapid growth VMSF using an assisted self-assembly method (EASA). The negative voltage applied during facilitated situ reduction GO to ErGO. synergistic effects ErGO, NGQDs, nanochannels led nearly tenfold enhancement signal compared that obtained on electrodes modified either ErGO or alone. realized linear concentration range from 0.1 10 μM, 100 μM. limit (LOD), determined based signal-to-noise ratio three ( S / N = 3), found be 81 nM. Combined size-exclusion property VMSF, demonstrated high selectivity, making it suitable samples.

Language: Английский

Sensitive Detection of Biomarker in Gingival Crevicular Fluid Based on Enhanced Electrochemiluminescence by Nanochannel-Confined Co3O4 Nanocatalyst DOI Creative Commons
Changfeng Zhu,

Yujiao Zhao,

Jiyang Liu

et al.

Biosensors, Journal Year: 2025, Volume and Issue: 15(1), P. 63 - 63

Published: Jan. 19, 2025

The sensitive detection of inflammatory biomarkers in gingival crevicular fluid (GCF) is highly desirable for the evaluation periodontal disease. Luminol-based electrochemiluminescence (ECL) immunosensors offer a promising approach fast and convenient biomarkers. However, luminol’s low ECL efficiency under neutral conditions remains challenge. This study developed an immunosensor by engineering immunorecognition interface on outer surface mesoporous silica nanochannel film (SNF) confining Co3O4 nanocatalyst within SNF nanochannels to improve luminol efficiency. was grown indium tin oxide (ITO) electrode using simple Stöber solution growth method. A successfully confined through situ electrodeposition, confirmed X-ray photoelectron spectroscopy (XPS) electrochemical measurements. demonstrated excellent electrocatalytic activity, effectively enhancing H2O2 oxidation boosting signal conditions. Using interleukin-6 (IL-6) as proof-of-concept demonstration, epoxy functionalization enabled covalent immobilization capture antibodies, forming specific interface. IL-6 binding induced immunocomplex formation, which reduced allowed quantitative detection. showed linear range from 1 fg mL−1 10 ng mL−1, with limit (LOD) 0.64 mL−1. It also good selectivity anti-interference capabilities, enabling successful artificial GCF samples.

Language: Английский

Citations

4
Electrochemical/Electrochemiluminescence Sensors Based on Vertically‐Ordered Mesoporous Silica Films for Biomedical Analytical Applications DOI
Fan Xue, Jiayi Wu, Tongtong Zhang

et al.

ChemBioChem, Journal Year: 2024, Volume and Issue: unknown

Published: June 14, 2024

Abstract Vertically‐ordered mesoporous silica films (VMSF, also named as isoporous membranes) have shown tremendous potential in the field of electroanalytical sensors due to their unique features terms controllable and ultrasmall nanopores, high molecular selectivity permeability, mechanical stability. This review will present recent progress on biomedical analytical applications VMSF, focusing small biomolecules, diseases‐related biomarkers, drugs cancer cells. Finally, conclusions with developments future perspective VMSF relevant fields be envisioned.

Language: Английский

Citations

11
In Vivo Electrochemical Biosensing Technologies for Neurochemicals: Recent Advances in Electrochemical Sensors and Devices DOI

Tuo Yang,

Tongjun Shen,

Bin Duan

et al.

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 2, 2025

In vivo electrochemical sensing of neurotransmitters, neuromodulators, and metabolites plays a critical role in real-time monitoring various physiological or psychological processes the central nervous system. Currently, advanced biosensors technologies have been emerging as prominent ways to meet surging requirements neurotransmitters neuromodulators ranging from single cells brain slices, even entire brain. This review introduces fundamental working principles summarizes achievements biosensing including voltammetry, amperometry, potentiometry, field-effect transistor (FET), organic (OECT). According elaborate feature technology, versatile strategies devoted solve issues associated with neurochemicals under an intricate environment. Voltammetry is universal technique investigate complex matrices which could realize miniaturization electrodes, while amperometry serves well-suited approach offering high temporal resolution favorable for fast oxidation–reduction kinetics neurochemicals. Potentiometry realizes quantitative analysis by recording potential difference reduced invasiveness compatibility. FET OECT serve amplification higher sensitivity than traditional technologies. Furthermore, we point out current shortcomings address challenges perspectives

Language: Английский

Citations

1
Ratiometric colorimetric and fluorometric dual-sensing system based on anthracene derivatives for the determination of ClO− and total antioxidant capacity DOI
Yan Zhang, Boyin Yan, Bing Liu

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113234 - 113234

Published: March 1, 2025

Language: Английский

Citations

0
Highly sensitive electrochemical immunosensor based on methylene blue-reduced graphene oxide nanocomposites as signal probes for IL-6 detection in gingival crevicular fluid samples DOI Creative Commons
Changfeng Zhu, Hongxin Wang, Jiyang Liu

et al.

Frontiers in Chemistry, Journal Year: 2025, Volume and Issue: 13

Published: April 2, 2025

As an important inflammatory cytokine, interleukin-6 (IL-6) can mediate the entire pathological process of periodontitis and is closely associated with degree inflammation. Therefore, it critical to develop convenient quantitative methods for monitoring IL-6 quantity in gingival crevicular fluid. In this study, methylene blue (MB)-decorated reduced graphene oxide (rGO) employed as signal probe further support antibody-enabling specific recognition IL-6. Due π-π stacking electrostatic interactions, rGO-MB nanocomposites be stably obtained. rGO good conductivity large surface area characteristics promotes redox signals MB on glassy carbon electrode (GCE). addition, through simple situ self-polymerization dopamine, polydopamine (PDA) obtained not only directly used a biological crosslinking agent covalent immobilization anti-IL-6 antibody but also regarded protective layer enhance stability GCE surface. Such designed PDA/rGO-MB/GCE-based immunosensor enables binding produces decreased electrochemical MB, realizing selective sensitive measurement Consequently, our fabricated has excellent linear relationship ranging from 1 pg/mL 100 ng/mL, limit detection low 0.48 pg/mL. Moreover, as-prepared sensing strategy shows accurate fluid samples.

Language: Английский

Citations

0
Simple and direct electrochemical detection of rosmarinic acid in food samples based on nanochannel modified carbon electrode DOI Creative Commons
Wenbo Chen,

Hongjuan Ru,

Fei Yan

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(26), P. 18599 - 18607

Published: Jan. 1, 2024

A simple electrochemical sensor was developed by integrating a vertically-ordered mesoporous silica film (VMSF) with pre-activated glassy carbon electrode (p-GCE) to provide dual signal amplification for sensitive detection of rosmarinic acid.

Language: Английский

Citations

3
Smartphone-assisted portable amperometric immunosensor based on CoMn-LDH for the visualized detection of tylosin DOI
Fenghe Duan, Yifei Wang, Bin Hu

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: 204, P. 110970 - 110970

Published: June 12, 2024

Language: Английский

Citations

2
Amino-functionalized vertically ordered mesoporous silica film on electrochemically polarized screen-printed carbon electrodes for the construction of gated electrochemical aptasensors and sensitive detection of carcinoembryonic antigens DOI Creative Commons

Ke He,

Hongxin Wang, T. Luo

et al.

Frontiers in Chemistry, Journal Year: 2024, Volume and Issue: 12

Published: Nov. 11, 2024

Disposable electrochemical biosensors with high sensitivity are very fit for point-of-care testing in clinical diagnosis. Herein, amino-functionalized, vertically ordered mesoporous silica films (NH

Language: Английский

Citations

2
Sensitive detection of gallic acid in food by electrochemical sensor fabricated by integrating nanochannel film with nanocarbon nanocomposite DOI Creative Commons
Jiasheng Li,

Jiahui Lin,

Tao Luo

et al.

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: Nov. 12, 2024

Sensitive detection of gallic acid (GA) in foods is great significance for assessing the antioxidant properties products and ensuring consumer health. In this work, a simple electrochemical sensor was conveniently fabricated by integrating vertically-ordered mesoporous silica film (VMSF) with electrochemically reduced graphene oxide (ErGO) nitrogen quantum dots (NGQDs) nanocomposite, enabling sensitive GA food sample. A water-soluble mixture (GO) NGQDs drop-cast onto common carbon electrode, glassy electrode (GCE), followed rapid growth VMSF using an assisted self-assembly method (EASA). The negative voltage applied during facilitated situ reduction GO to ErGO. synergistic effects ErGO, NGQDs, nanochannels led nearly tenfold enhancement signal compared that obtained on electrodes modified either ErGO or alone. realized linear concentration range from 0.1 10 μM, 100 μM. limit (LOD), determined based signal-to-noise ratio three ( S / N = 3), found be 81 nM. Combined size-exclusion property VMSF, demonstrated high selectivity, making it suitable samples.

Language: Английский

Citations

0