Phytochemical Profile and Antioxidant Activity of the Tuber and Peel of Pachyrhizus erosus

Antioxidants, Journal Year: 2025, Volume and Issue: 14(4), P. 416 - 416

Published: March 31, 2025

This study systematically investigated the antioxidant activities and phytochemical profiles of petroleum ether (PE), ethyl acetate (EtOAc), n-butanol (n-BuOH) aqueous fractions edible (tubers) non-edible portions (peels) Pachyrhizus erosus. The results showed that both tubers peels from P. erosus were rich in polyphenols flavonoids, whereas EtOAc fraction had highest polyphenol content, PE total flavonoid content. ABTS, DPPH, FRAP assays revealed significant activity, possessed better activity than tubers. UPLC-Orbitrap-MS/MS analysis indicated thirty compounds identified tubers, including twenty-one six phenolics, two coumarins, one lignan, some which have previously been to display anti-inflammatory effects via Nrf2-Keap1 NF-κB signaling pathways. These findings provide robust scientific evidence for health-promoting properties pharmaceutical potential erosus, its portion has great use as a natural food, cosmetic, industries.

Language: Английский

Verification of the mechanism of action of isoliquiritigenin derivatives on LPS-induced FLS cells in rheumatoid arthritis based on network pharmacology

Bioorganic & Medicinal Chemistry, Journal Year: 2025, Volume and Issue: 124, P. 118199 - 118199

Published: April 17, 2025

Language: Английский