Food and Bioprocess Technology, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 21, 2024
Language: Английский
Composites Part B Engineering, Journal Year: 2024, Volume and Issue: unknown, P. 111928 - 111928
Published: Oct. 1, 2024
Language: Английский
Citations
4
Molecules, Journal Year: 2025, Volume and Issue: 30(1), P. 174 - 174
Published: Jan. 4, 2025
Inflammation, oxidative stress, and metabolic diseases are intricately linked in a complex, self-reinforcing relationship. Inflammation can induce while stress trigger inflammatory responses, creating cycle that contributes to the development progression of disorders; addition, these effects be observed at systemic local scales. Both processes lead cellular damage, mitochondrial dysfunction, insulin resistance, particularly affecting adipose tissue, liver, muscles, gastrointestinal tract. This results impaired function energy production, contributing conditions such as type 2 diabetes, obesity, syndrome. Legumes good source phenolic compounds anthocyanins exert an antioxidant effect—they directly neutralize reactive oxygen species free radicals, reducing stress. In vivo, vitro, clinical trial studies demonstrate modulate key signaling pathways involved inflammation metabolism, improving sensitivity regulating lipid glucose metabolism. They also anti-inflammatory by inhibiting proinflammatory enzymes cytokines. Additionally, phenolics may positively influence gut microbiome, indirectly metabolism inflammation.
Language: Английский
Citations
0
Food Chemistry, Journal Year: 2025, Volume and Issue: 473, P. 143007 - 143007
Published: Jan. 22, 2025
Language: Английский
Citations
0
Fermentation, Journal Year: 2025, Volume and Issue: 11(3), P. 145 - 145
Published: March 14, 2025
Morus nigra L. is rich in anthocyanins and other active ingredients, but its extraction residues pose a burden on the environment. In present study, residue resource utilization was achieved through liquid fermentation of Schizophyllum commune, with aim enhancing anthocyanin solubilization evaluating anti-inflammatory activity. Response surface methodology used to optimize parameters quantify fractions by HPLC. The effect evaluated using lipopolysaccharide-induced inflammation model human foreskin fibroblast (BJ cell), interaction cyanidin-3-O-glucoside (C3G) NLRP3, key target pyroptosis pathway, resolved molecular docking. Our results indicated that optimal conditions (substrate 3.4%, inoculum 9%, time 50 h) enabled total reach 85.1 μg/mL, which C3G content elevated 66.7 μg/mL (release efficiency 83.9%). fermented filtrate effectively promoted BJ cell proliferation inhibited inflammatory response, signaling pathway playing significant role. Molecular docking confirmed binds strongly NLRP3 protein. This technology provides new strategy for high-value development natural drugs.
Language: Английский
Citations
0
Processes, Journal Year: 2024, Volume and Issue: 12(11), P. 2444 - 2444
Published: Nov. 5, 2024
The continued use of synthetic additives in food production and preservation has raised concerns among consumers, given their potential negative health effects. Researchers industry experts have been exploring plants with potent functional compounds as an alternative source natural such anthocyanins, which can be utilized to produce safe additives. Given various biological activities, great exists for anthocyanins used preserve or foods benefits. However, fully realize the economic benefits a deep understanding different plant sources well composition, extraction techniques, function products, is warranted. Therefore, this paper critically reviews application nutraceutical industries, highlighting emerging benefits, challenges industry. This review also offers insights that could future research help establish novel sustainable methods manufacturing anthocyanin-based value-added products ingredients.
Language: Английский
Citations
2
Food and Bioprocess Technology, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 21, 2024
Language: Английский
Citations
1