Bovine Colostrum in Pediatric Nutrition and Health DOI Open Access

Ahmet Alperen Canbolat,

Mauro Lombardo, Alicia del Carmen Mondragón

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(24), P. 4305 - 4305

Published: Dec. 13, 2024

Bovine colostrum (BC), the first milk secreted by mammals after birth, is a trending alternative source for supplementing infants and children, offering benefits gut immune health. Its rich components, such as proteins, immunoglobulins, lactoferrin, glycans, are used to fortify diets support development. Preterm development crucial, especially in maturation of essential systems, from 2010 2020, approximately 15% all premature births occurred at less than 32 weeks gestation worldwide. This review explores composition, benefits, effects BC on general along with preterm who require special care, highlights its role growth also associated specific pediatric diseases, including necrotizing enterocolitis (NEC), infectious diarrhea, inflammatory bowel disease (IBD), short-bowel syndrome (SBS), neonatal sepsis, gastrointestinal respiratory infections, some minor conditions. discusses clinical trials regarding these conditions which occasionally encountered infants. The anti-inflammatory, antimicrobial, immunomodulatory, antiviral properties discussed, emphasizing mechanisms action. Clinical trials, particularly humans, provide evidence supporting inclusion formulas diets, although precise standards age, feeding time, amounts needed ensure safety efficacy. However, potential adverse effects, allergic reactions caseins immunoglobulin E, must be considered. More comprehensive necessary expand infant feeding, important components BC, should further studied their synergistic diseases. Ultimately, shows promise health incorporated into nutritional supplements caution.

Language: Английский

Bovine Colostrum in Pediatric Nutrition and Health DOI Open Access

Ahmet Alperen Canbolat,

Mauro Lombardo, Alicia del Carmen Mondragón

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(24), P. 4305 - 4305

Published: Dec. 13, 2024

Bovine colostrum (BC), the first milk secreted by mammals after birth, is a trending alternative source for supplementing infants and children, offering benefits gut immune health. Its rich components, such as proteins, immunoglobulins, lactoferrin, glycans, are used to fortify diets support development. Preterm development crucial, especially in maturation of essential systems, from 2010 2020, approximately 15% all premature births occurred at less than 32 weeks gestation worldwide. This review explores composition, benefits, effects BC on general along with preterm who require special care, highlights its role growth also associated specific pediatric diseases, including necrotizing enterocolitis (NEC), infectious diarrhea, inflammatory bowel disease (IBD), short-bowel syndrome (SBS), neonatal sepsis, gastrointestinal respiratory infections, some minor conditions. discusses clinical trials regarding these conditions which occasionally encountered infants. The anti-inflammatory, antimicrobial, immunomodulatory, antiviral properties discussed, emphasizing mechanisms action. Clinical trials, particularly humans, provide evidence supporting inclusion formulas diets, although precise standards age, feeding time, amounts needed ensure safety efficacy. However, potential adverse effects, allergic reactions caseins immunoglobulin E, must be considered. More comprehensive necessary expand infant feeding, important components BC, should further studied their synergistic diseases. Ultimately, shows promise health incorporated into nutritional supplements caution.

Language: Английский

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