Role of Flavonoids in Protecting Against Neurodegenerative Diseases—Possible Mechanisms of Action DOI Open Access
Elżbieta Rębas

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(10), P. 4763 - 4763

Published: May 16, 2025

Neurodegenerative and mood disorders represent growing medical social problems, many of which are produced by oxidative stress, neuroinflammation, disruption in the metabolism various neurotransmitters, some disturbances lipid/carbohydrate homeostasis. Biologically active plant compounds, including flavonoids, have been shown to exert a positive impact on central nervous system function. This review assesses studies naturally occurring flavonoids belonging polyphenol subclasses their mechanisms neuroprotective action, especially against neurodegenerative such as Alzheimer’s disease Parkinson’s disease. Most studied phytochemicals possess anti-oxidative, anti-inflammatory, properties. These considered compounds that reduce risk developing diseases can be used treatment neurological diseases. The actions may entail regulate reactive oxygen species generation modify inflammatory pathways, they should therapeutic agents.

Language: Английский

Harnessing Potential of Liposomal Drug Carriers for Enhanced Pharmacokinetic Profile of Flavonoids DOI
Nazir Hussain, S. K. Dubey,

C.K. Katiyar

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 106978 - 106978

Published: April 1, 2025

Language: Английский

Citations

0

A dual approach to flavonoid toxicity assessment: Bridging computational and experimental paradigms DOI

Mriganka Das,

Sibashish Kityania,

P. D. Nath

et al.

Computational Toxicology, Journal Year: 2025, Volume and Issue: unknown, P. 100355 - 100355

Published: May 1, 2025

Language: Английский

Citations

0

Role of Flavonoids in Protecting Against Neurodegenerative Diseases—Possible Mechanisms of Action DOI Open Access
Elżbieta Rębas

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(10), P. 4763 - 4763

Published: May 16, 2025

Neurodegenerative and mood disorders represent growing medical social problems, many of which are produced by oxidative stress, neuroinflammation, disruption in the metabolism various neurotransmitters, some disturbances lipid/carbohydrate homeostasis. Biologically active plant compounds, including flavonoids, have been shown to exert a positive impact on central nervous system function. This review assesses studies naturally occurring flavonoids belonging polyphenol subclasses their mechanisms neuroprotective action, especially against neurodegenerative such as Alzheimer’s disease Parkinson’s disease. Most studied phytochemicals possess anti-oxidative, anti-inflammatory, properties. These considered compounds that reduce risk developing diseases can be used treatment neurological diseases. The actions may entail regulate reactive oxygen species generation modify inflammatory pathways, they should therapeutic agents.

Language: Английский

Citations

0