Sustainable Hydrogenation of Xylose to Xylitol Using Nickel-Alumina Catalysts Supported on Hexagonal Mesoporous Silica in Water vis-à-vis Aqueous Isopropanol as Solvent

Catalysis Today, Journal Year: 2024, Volume and Issue: unknown, P. 115105 - 115105

Published: Oct. 1, 2024

Language: Английский

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Synergistic Antimicrobial Activity of Magnetite and Vancomycin-Loaded Mesoporous Silica Embedded in Alginate Films

Gels, Journal Year: 2023, Volume and Issue: 9(4), P. 295 - 295

Published: April 2, 2023

The aim of the present study was to obtain a hydrogel-based film as carrier for sustained and controlled release vancomycin, an antibiotic commonly used in various types infections. Considering high-water solubility vancomycin (>50 mg/mL) aqueous medium underlying exudates, prolonged from MCM-41 sought. work focused on synthesis malic acid coated magnetite (Fe3O4/malic) by co-precipitation, sol-gel method loading with their use alginate films wound dressing. nanoparticles obtained were physically mixed embedded gel. Prior incorporation, characterized XRD, FT-IR FT-Raman spectroscopy, TGA-DSC DLS. prepared simple casting further cross-linked examined possible heterogeneities means microscopy SEM. degree swelling water vapor transmission rate determined, considering potential dressings. show morpho-structural homogeneity, over 48 h strong synergistic enhancement antimicrobial activity consequence hybrid nature these films. efficacy tested against S. aureus, two strains E. faecalis (including vancomycin-resistant Enterococcus, VRE) C. albicans. incorporation also considered external triggering component case magneto-responsive smart dressing stimulate diffusion.

Language: Английский

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Synthesis of Nanosilica for the Removal of Multicomponent Cd2+ and Cu2+ from Synthetic Water: An Experimental and Theoretical Study

Molecules, Journal Year: 2022, Volume and Issue: 27(21), P. 7536 - 7536

Published: Nov. 3, 2022

Copper and cadmium ions are among the top 120 hazardous chemicals listed by Agency for Toxic Substances Disease Registry (ATSDR) that can bind to organic inorganic chemicals. Silica is one of most abundant oxides limit transport these into water resources. Limited work has focused on assessing applicability nanosilica removal multicomponent metal studying their interaction surface this adsorbent. Therefore, study focuses utilizing a adsorption Cd2+ Cu2+ from water. Experimental single- multi-component was conducted supported with theoretical interpretations. The characterized its area, morphology, crystallinity, functional groups. BET area 307.64 m2/g total pore volume 4.95×10-3 cm3/g. SEM showed an irregular amorphous shape slits cavities. Several Si-O-Si hydroxyl groups were noticed silica. single isotherm experiment higher uptake (72.13 mg/g) than (29.28 mg/g). equilibrium shows affinity surface. This decreases increasing concentration due isosteric heat between Cd experimental data modeled using isotherms adsorption, Freundlich non-modified competitive Langmuir models showing best fit. molecular dynamics simulations support where multilayer coverage. provides insight removing heavy metals

Language: Английский

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Very Large Pores Mesoporous Silica as New Candidate for Delivery of Big Therapeutics Molecules, Such as Pharmaceutical Peptides

Materials, Journal Year: 2023, Volume and Issue: 16(11), P. 4151 - 4151

Published: June 2, 2023

The synthesis of a scaffold that can accommodate big molecules with pharmaceutical role is important to shield them and maintain their biological activity. In this field, silica particles large pores (LPMS) are innovative supports. Large allow for the loading bioactive inside structure contemporarily stabilization protection. These purposes cannot be achieved using classical mesoporous (MS, pore size 2-5 nm), because not enough blocking occurs. LPMSs different porous structures synthesized starting from an acidic water solution tetraethyl orthosilicate reacting agents (Pluronic® F127 mesitylene), performing hydrothermal microwave-assisted reactions. Time surfactant optimization were performed. Loading tests conducted Nisin as reference molecule (polycyclic antibacterial peptide, dimensions 4-6 nm); UV-Vis analyses on solutions For LPMSs, significantly higher efficiency (LE%) was registered. Other (Elemental Analysis, Thermogravimetric Analysis UV-Vis) confirmed presence in all its stability when loaded them. showed lower decrease specific surface area if compared MS; terms difference LE% between samples, it explained considering filling phenomenon allowed MSs. Release studies simulated body fluid highlight, only controlled release, longer time scale release. Scanning Electron Microscopy images acquired before after release shows LPMSs' maintenance structure, demonstrating strength mechanical resistance structures. conclusion, synthesized, optimization. better releasing properties respect MS. All collected data confirm MS in-pore LPMS.

Language: Английский

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Nano Phyto-Phenols as potential immunomodulators: A review

Food and Humanity, Journal Year: 2023, Volume and Issue: 1, P. 809 - 816

Published: Aug. 2, 2023

Language: Английский

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