Protein‐Based Face Mask with High SARS‐CoV‐2 Neutralization Ability and Breathability DOI Creative Commons
Bao‐Zhong Zhang,

Yee‐Man Au‐Yeung,

Terrence Tsz‐Tai Yuen

et al.

Advanced Materials Technologies, Journal Year: 2023, Volume and Issue: 8(18)

Published: July 23, 2023

Abstract Current intramuscular vaccines cannot effectively prevent severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) transmission and infection in nasal epithelium. Although face masks represent an additional preventive measure against SARS‐CoV‐2, their low breathability hinders wearing compliance. Herein, the development of SuperNeut, a protein‐based breathable high‐efficiency mask, is reported. The mask contains KP‐LCB1, fusion protein that can capture SARS‐CoV‐2 spike proteins on one end attach to keratin fibres other. meltblown fabric replaced by thin electrospun layer allows uniform adhesion which serves as effective barrier filter incoming viruses, while substantially improving breathability. studies demonstrate stable efficiently neutralise multiple wildtype (WT), Alpha (B.1.1.7), Delta (B.1.617.2), Omicron (B.1.1.529). SuperNeut compared commercial surgical also quantified. Importantly, it shown Mask able Syrian hamster model. Overall, highly transmission. This design proof‐of‐concept designs be improved with biological components. neutralising this altered combat future disease outbreaks.

Language: Английский

Prospective Life Cycle Assessment of Emerging Silver Nanoparticle Synthesis Methods: One-Pot Polyethyleneimine Chemical Reduction and Biological Reductions DOI Creative Commons
Ziyi Han, Heng Yi Teah, Izumi Hirasawa

et al.

Journal of Cleaner Production, Journal Year: 2025, Volume and Issue: 494, P. 145012 - 145012

Published: Feb. 1, 2025

Language: Английский

Citations

0
Adding antibacterial/antiviral properties to medical purpose materials by modification with silver and copper nanoparticles DOI
А. В. Руденко,

L. D. Kisterska,

O. B. Loginova

et al.

Himia Fizika ta Tehnologia Poverhni, Journal Year: 2025, Volume and Issue: 16(1), P. 63 - 74

Published: March 6, 2025

In modern times, especially during epidemics and pandemics, respiratory protection becomes important. One of the most effective means against airborne infections such as influenza, SARS, COVID-19 is 3-layer medical mask. The aim this research to modify purpose materials with Ag NPs a mixture Cu give their surface antibacterial/antiviral properties. study adsorption properties fabrics (using BET method for determining specific area distribution pores by size depending on radius in tested fabric sample) has shown that characterized presence micro-, meso-, macropores, which why, addition its high capacity various substances, it can be used modification using from solutions. nanoparticles are encapsulated porous structure tissue retained mesopores 2–50 nm due action capillary forces. To properties, water-glycerol nanosuspension bicomponent were applied solution. fabric, we implanted physically ion-plasma technology an environmentally friendly technological cycle, ELIPS technology) into food glycerol stabilized without slightest additional chemical reagents. initial suspension structural transformations immobilized studied electron microscopy micro-X-ray spectral analysis. results comprehensive antiviral, antimicrobial, antimycotic activity bactericidal, fungicidal, virucidal effects observed at NP concentration 10 ppm. composites silicon dioxide more active inhibiting growth both Gram-negative Gram-positive bacteria than those NPs. Thus, NP-modified recommended manufacture middle layer masks, dressings, underwear pads, baby nappies diapers, bedding, uniforms, other types products.

Language: Английский

Citations

0
Nanotechnological Advancements in the Development of Antimicrobial PPE DOI Open Access

Subramanian Sundaramoorthy

Published: March 4, 2025

Language: Английский

Citations

0
Design and Manufacturing of Antibacterial Electrospun Polysulfone Membranes Functionalized by Ag Nanocoating via Magnetron Sputtering DOI Creative Commons
Noemi Fiaschini,

Chiara Giuliani,

Roberta Vitali

et al.

Nanomaterials, Journal Year: 2022, Volume and Issue: 12(22), P. 3962 - 3962

Published: Nov. 10, 2022

Antibacterial properties of engineered materials are important in the transition to a circular economy and societal security, as they central many key industrial areas, such health, food, water treatment/reclaiming. Nanocoating electrospinning two versatile, simple, low-cost technologies that can be combined into new advanced manufacturing approaches achieve controlled production innovative micro- nano-structured non-woven membranes with antifouling antibacterial properties. The present study investigates rational approach design manufacture electrospun polysulfone (PSU) mechanical optimized via combinatorial testing from factorial experiments (DOE) endowed antimicrobial silver (Ag) nanocoating. Despite very low amount Ag deposited conformal percolating nanocoating web on polymer fibers, resistance assessed against Gram-negative bacteria E. coli proved extremely effective, almost completely inhibiting microbial proliferation respect reference uncoated PSU membrane. results relevant, for example, improve behavior ultrafiltration reverse osmosis treatment.

Language: Английский

Citations

10
Protein‐Based Face Mask with High SARS‐CoV‐2 Neutralization Ability and Breathability DOI Creative Commons
Bao‐Zhong Zhang,

Yee‐Man Au‐Yeung,

Terrence Tsz‐Tai Yuen

et al.

Advanced Materials Technologies, Journal Year: 2023, Volume and Issue: 8(18)

Published: July 23, 2023

Abstract Current intramuscular vaccines cannot effectively prevent severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) transmission and infection in nasal epithelium. Although face masks represent an additional preventive measure against SARS‐CoV‐2, their low breathability hinders wearing compliance. Herein, the development of SuperNeut, a protein‐based breathable high‐efficiency mask, is reported. The mask contains KP‐LCB1, fusion protein that can capture SARS‐CoV‐2 spike proteins on one end attach to keratin fibres other. meltblown fabric replaced by thin electrospun layer allows uniform adhesion which serves as effective barrier filter incoming viruses, while substantially improving breathability. studies demonstrate stable efficiently neutralise multiple wildtype (WT), Alpha (B.1.1.7), Delta (B.1.617.2), Omicron (B.1.1.529). SuperNeut compared commercial surgical also quantified. Importantly, it shown Mask able Syrian hamster model. Overall, highly transmission. This design proof‐of‐concept designs be improved with biological components. neutralising this altered combat future disease outbreaks.

Language: Английский

Citations

1