Chiral nanosystem and chiral supraparticles for drug delivery: an expert opinion DOI
Mahfoozur Rahman, Jagdish Singh, Alhussain Aodah

et al.

Expert Opinion on Drug Delivery, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 17, 2024

Introduction Chiral nanocarriers enhance therapeutic efficacy by improving in vivo stability and cellular uptake. Chemical functionalization reduces cytotoxicity, resulting favorable biocompatibility. Nanoparticles self-assemble into supraparticles, enhancing drug delivery through improved retention loading. Area covered This review covers chiral nanostructures their mechanisms, applications various healthcare applications. Expert Opinion The chirality of biomaterials is crucial for advancing nanomedicine. nanosystem interacting selectively with biological molecules, specificity efficacy. off-target effects improves outcomes. Research has focused on uptake elimination to ensure safety, nanomaterials also show promise optical sensing gene editing. Their biocompatibility ability supraparticles may make them ideal systems.

Language: Английский

Review of Advances in Coating and Functionalization of Gold Nanoparticles: From Theory to Biomedical Application DOI Creative Commons
Wilmmer Alexander Arcos Rosero, Angélica Bueno Barbezan, Carla Daruich de Souza

et al.

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(2), P. 255 - 255

Published: Feb. 9, 2024

Nanoparticles, especially gold nanoparticles (Au NPs) have gained increasing interest in biomedical applications. Used for disease prevention, diagnosis and therapies, its significant advantages therapeutic efficacy safety been the main target of interest. Its application immune system stability physiological environments cell membranes, low toxicity optimal bioperformances are critical to success engineered nanomaterials. unique optical properties great attractors. Recently, several physical chemical methods coating these NPs widely used. Biomolecules such as DNA, RNA, peptides, antibodies, proteins, carbohydrates biopolymers, among others, used coatings Au various applications, thus their biocompatibility while maintaining biological functions. This review mainly presents a general representative view different types NP functionalization using biomolecules, strategies mechanisms.

Language: Английский

Citations

30
Advances in chiral gold nanoparticles and their applications in biomedical photonics DOI

Anyu Yue,

Qian Wang,

Yulong Weng

et al.

Chinese Science Bulletin (Chinese Version), Journal Year: 2023, Volume and Issue: 68(27), P. 3582 - 3593

Published: July 3, 2023

Language: Английский

Citations

2
Chiral nanosystem and chiral supraparticles for drug delivery: an expert opinion DOI
Mahfoozur Rahman, Jagdish Singh, Alhussain Aodah

et al.

Expert Opinion on Drug Delivery, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 17, 2024

Introduction Chiral nanocarriers enhance therapeutic efficacy by improving in vivo stability and cellular uptake. Chemical functionalization reduces cytotoxicity, resulting favorable biocompatibility. Nanoparticles self-assemble into supraparticles, enhancing drug delivery through improved retention loading. Area covered This review covers chiral nanostructures their mechanisms, applications various healthcare applications. Expert Opinion The chirality of biomaterials is crucial for advancing nanomedicine. nanosystem interacting selectively with biological molecules, specificity efficacy. off-target effects improves outcomes. Research has focused on uptake elimination to ensure safety, nanomaterials also show promise optical sensing gene editing. Their biocompatibility ability supraparticles may make them ideal systems.

Language: Английский

Citations

0