Journal of Pharmaceutical Investigation,
Journal Year:
2024,
Volume and Issue:
54(6), P. 751 - 783
Published: Aug. 2, 2024
Abstract
Background
Nanometal-organic
frameworks
(nano-MOFs),
which
exhibit
distinctive
features,
such
as
controlled
release
mechanisms,
stimuli-responsive
behaviors,
and
sustained
drug
profiles,
have
emerged
promising
candidates
for
next-generation
delivery
systems.
Area
covered
This
review
outlines
the
impact
of
nano-MOFs
in
biomedical
applications,
emphasizing
their
potential
targeted
through
active
strategies
biocompatibility
considerations.
Expert
opinion
The
versatility
tunability
pave
way
personalized
medicine,
allowing
tailored
formulations
to
meet
individual
patient
needs.
Despite
transformative
potential,
challenges
remain
terms
stability,
toxicity
assessment,
standardization.
As
progress
from
laboratory
research
clinical
trials,
they
present
a
paradigm
shift
delivery,
offering
precision
medicine
solutions
theranostic
platforms.
future
holds
promise
use
revolutionize
ushering
an
era
effective
therapeutic
interventions.
Nanomaterials,
Journal Year:
2024,
Volume and Issue:
14(1), P. 110 - 110
Published: Jan. 2, 2024
Although
Zr-based
metal-organic
frameworks
(MOFs)
exhibit
robust
chemical
and
physical
stability
in
the
presence
of
moisture
acidic
conditions,
their
susceptibility
to
nucleophilic
attacks
from
bases
poses
a
critical
challenge
overall
stability.
Herein,
we
systematically
investigate
UiO-66
(UiO
=
University
Oslo)
MOFs
basic
solutions.
The
impact
11
standard
bases,
including
inorganic
salts
organic
on
these
is
examined.
destruction
framework
confirmed
through
powder
X-ray
diffraction
(PXRD)
patterns,
monitored
dissolution
ligands
assessed
using
nuclear
magnetic
resonance
(NMR)
spectroscopy.
Our
key
findings
reveal
direct
correlation
between
strength
concentration
base
MOFs.
summarized
data
provide
valuable
insights
that
can
guide
practical
application
under
offering
essential
information
for
optimal
utilization
various
settings.
Biomimetics,
Journal Year:
2024,
Volume and Issue:
9(3), P. 153 - 153
Published: March 1, 2024
The
rehabilitation
of
alveolar
bone
defects
moderate
to
severe
size
is
often
challenging.
Currently,
the
therapeutic
approaches
used
include,
among
others,
guided
regeneration
technique
combined
with
various
grafts.
Although
these
techniques
are
widely
applied,
several
limitations
and
complications
have
been
reported
such
as
morbidity,
suboptimal
graft/membrane
resorption
rate,
low
structural
integrity,
dimensional
stability.
Thus,
development
biomimetic
scaffolds
tailor-made
characteristics
that
can
modulate
cell
tissue
interaction
may
be
a
promising
tool.
This
article
presents
critical
consideration
in
scaffold’s
design
while
also
providing
information
on
fabrication
methods
nanosystems.
Their
utilization
delivery
systems
will
mentioned.
ChemEngineering,
Journal Year:
2025,
Volume and Issue:
9(2), P. 24 - 24
Published: Feb. 24, 2025
Asthma
and
allergic
rhinitis
(AR)
stand
as
prevalent
chronic
ailments
impacting
children
within
the
United
States.
It
is
approximated
that
many
40%
of
American
exhibit
symptoms
indicative
AR,
a
condition
which,
if
inadequately
managed,
could
potentially
lead
to
onset
additional
illnesses
such
asthma,
rhinosinusitis,
conjunctivitis,
otitis
media.
We
have
devised
universal
synthetic
pathway
encapsulate
small
molecules
montelukast
sodium
Metal–Organic
Frameworks
(MOFs)
for
treatment
asthma
AR.
Two
distinct
Cu-MOFs,
namely
single
linker
mixed
MOFs,
were
synthesized
through
solvothermal
method
utilizing
1,4-benzenedioic
acid
(BDC)
4,4′-dipyridile
linkers.
The
Cu-MOFs
underwent
thorough
examination
employing
various
analytical
techniques
including
BET,
SEM,
FTIR,
PXRD.
These
MOFs
hold
promise
potential
vehicles
drug
delivery
applications.
Various
proportions
Cu-MOF-1
Cu-MOF-2
dispersed
alongside
sodium.
Notably,
1:1
ratio
both
exhibited
enhanced
absorption
compared
other
ratios.
Furthermore,
demonstrated
superior
overall
when
contrasted
with
Cu-MOF-1.
This
investigation
also
delves
into
release
dynamics
from
different
ratios
drug.
analysis
was
conducted
in
phosphate-buffered
saline
(PBS)
solution
pH
7.4,
absorbance
values
measured
using
UV-visible
spectrometer
at
time
intervals.
Drug
are
effectively
encapsulated
demonstrate
controlled
establishment
hydrogen
bonding
or
π–π
interactions
between
MOFs.
Despite
notable
advancements
utilization
biomedical
purposes,
enhancements
necessary
before
they
can
be
considered
viable
therapeutic
modalities.
Crystals,
Journal Year:
2023,
Volume and Issue:
13(8), P. 1236 - 1236
Published: Aug. 10, 2023
This
review
study
aims
to
present,
in
a
condensed
manner,
the
significance
of
use
crystalline
carbon-based
nanomaterials
biomedical
applications.
Crystalline
nanomaterials,
encompassing
graphene,
graphene
oxide,
reduced
carbon
nanotubes,
and
quantum
dots,
have
emerged
as
promising
materials
for
development
medical
devices
various
These
possess
inorganic
semiconducting
attributes
combined
with
organic
π-π
stacking
features,
allowing
them
efficiently
interact
biomolecules
present
enhanced
light
responses.
By
harnessing
these
unique
properties,
offer
opportunities
future
advancements
biomedicine.
Recent
studies
focused
on
targeted
drug
delivery,
cancer
treatment,
biosensors.
The
conjugation
modification
led
significant
plethora
therapies
addressed
limitations
preclinical
Furthermore,
wide-ranging
therapeutic
advantages
nanotubes
been
thoroughly
examined
context
Water,
Journal Year:
2023,
Volume and Issue:
15(15), P. 2773 - 2773
Published: July 31, 2023
Organic
pollutants
found
in
industrial
effluents
contribute
to
significant
environmental
risks.
Degradation
of
these
pollutants,
particularly
through
photocatalysis,
is
a
promising
strategy
ensuring
water
purification
and
supporting
wastewater
treatment.
Thus,
photodegradation
rhodamine
B
phenol
under
visible-light
irradiation
using
TiO2/SiO2
composite
nanoparticles
was
within
the
main
scopes
this
study.
The
nanocomposite
synthesized
wet
impregnation
method
TiO2
SiO2
nanopowders
previously
prepared
via
facile
sol–gel
approach
fully
characterized.
obtained
results
indicated
pure
anatase
phase,
coupled
with
increased
crystallinity
(85.22%)
relative
smaller
crystallite
size
(1.82
nm)
relation
an
enhanced
specific
surface
area
(50
m2/g)
reduced
energy
band
gap
(3.18
eV).
Photodegradation
upon
studied,
showing
that
reached
total
(100%)
degradation
210
min
compared
analogues,
which
achieved
≈45%
≈43%
rate,
respectively.
Similarly,
catalyst
presented
photocatalytic
performance
same
conditions
towards
phenol,
leading
43.19%
verifying
catalyst’s
selectivity
dye
as
well
its
efficiency
both
organic
compounds
SiO2.
Additionally,
based
on
acquired
experimental
results,
●O2−,
h+
e−
were
be
major
reactive
oxygen
species
involved
B’s
degradation,
while
●OH
radicals
pivotal
visible
irradiation.
Finally,
after
reused
five
times,
it
negligible
decrease
compounds.
Molecules,
Journal Year:
2023,
Volume and Issue:
28(18), P. 6681 - 6681
Published: Sept. 18, 2023
The
heavy
metal
contamination
of
water
systems
has
become
a
major
environmental
concern
worldwide.
Photocatalysis
using
metal-organic
frameworks
(MOFs)
emerged
as
promising
approach
for
remediation,
owing
to
the
ability
MOFs
fully
degrade
contaminants
through
redox
reactions
that
are
driven
by
photogenerated
charge
carriers.
This
review
provides
comprehensive
analysis
recent
developments
in
MOF-based
photocatalysts
removing
and
decontaminating
metals
from
water.
tunable
nature
allows
rational
design
composition
features
enhance
light
harvesting,
separation,
pollutant
absorptivity,
photocatalytic
activities.
Key
strategies
employed
include
coordination
tuning,
organic
ligand
functionalization,
heteroatom
doping,
plasmonic
nanoparticle
incorporation,
defect
engineering,
morphology
control.
mechanisms
involved
interactions
between
MOF
discussed,
including
absorption,
carrier
ion
adsorption,
reactions.
highlights
diverse
applications
treating
such
lead,
mercury,
chromium,
cadmium,
silver,
arsenic,
nickel,
etc.
remediation.
Kinetic
modeling
vital
insights
into
complex
interplay
coupled
processes
adsorption
degradation
influence
treatment
efficiency.
Life
cycle
assessment
(LCA)
is
also
crucial
evaluating
sustainability
technologies.
By
elucidating
latest
advances,
current
challenges,
future
opportunities,
this
potential
sustainable
technology
addressing
critical
issue
pollution
systems.
Ongoing
efforts
needed
address
issues
stability,
recyclability,
scalable
synthesis,
practical
reactor
engineering.
Advanced Optical Materials,
Journal Year:
2024,
Volume and Issue:
12(17)
Published: April 3, 2024
Abstract
Optoelectronics
and
photocatalysis
are
two
rapidly
developing
photonic
fields
that
revolutionizing
green
energy,
medicine,
communications,
robotics.
To
advance
these
areas
explore
new
applications,
there
is
a
need
for
materials
technologies
enable
fast,
scalable,
customizable
production
of
high‐performing
optoelectronics,
including
the
future
development
flexible
devices.
This
review
focused
on
strategies
to
synthesize
novel,
not
fully
explored
and/or
enhance
their
properties
using
powerful
method
laser
processing.
The
discussion
includes
treatment
MXenes,
Metal‐Organic
Frameworks,
perovskites,
materials'
advantages
in
terms
structural,
electronic,
optical
properties,
role
different
laser‐based
techniques
boosting
performance.
Additionally,
demonstration
existing
potential
applications
three
combinations,
especially
optoelectronics
photocatalytic
platforms.
aims
provide
comprehensive
understanding
current
state‐of‐the‐art
this
field
help
researchers
identify
opportunities
challenges
processing
emerging
nanomaterials
photocatalysis.
