ACS Nano, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 24, 2025
Surface-enhanced Raman scattering (SERS) is an analytical technique capable of detecting trace amounts specific species. The uniqueness vibrational signatures a major advantage SERS. This combination sensitivity and specificity has motivated researchers to develop diverse methodologies leveraging However, even 50 years after its first observation, SERS still perceived as unreliable for quantification. perception precluded the application in laboratories that rely on consistent quantification (for regulatory purposes, instance). In this review, we describe some aspects lead intensity variations how those challenges were addressed technique. goal identify sources intensities then demonstrate that, with these pitfalls, can be used when factors such nature substrate, experimental conditions, sample preparation, surface chemistry, data analysis are carefully considered tailored particular application.
Language: Английский