Published: Jan. 1, 2024
Language: Английский
Frontiers in Genome Editing, Journal Year: 2025, Volume and Issue: 7
Published: March 10, 2025
Climate change threatens global crop yield and food security due to rising temperatures, erratic rainfall, increased abiotic stresses like drought, heat, salinity. Gene editing technologies, including CRISPR/Cas9, base editors, prime offer precise tools for enhancing resilience. This review explores the mechanisms of these technologies their applications in developing climate-resilient crops address future challenges. While CRISPR/enables targeted modifications plant DNA, editors allow direct conversion without inducing double-stranded breaks, enable insertions, deletions, substitutions. By understanding manipulating key regulator genes involved stress responses, such as DREB, HSP, SOS, ERECTA, HsfA1, NHX; tolerance can be enhanced against salt stress. improve traits related root development, water use efficiency, response pathways, heat shock response, photosynthesis, membrane stability, ion homeostasis, osmotic adjustment, oxidative response. Advancements gene integration with genomics, phenomics, artificial intelligence (AI)/machine learning (ML) hold great promise. However, challenges off-target effects, delivery methods, regulatory barriers must addressed. highlights potential develop crops, contributing sustainable agriculture.
Language: Английский
Citations
1
Journal of Experimental Botany, Journal Year: 2024, Volume and Issue: 75(16), P. 4745 - 4759
Published: May 18, 2024
Transcription factors (TFs) intricately govern cellular processes and responses to external stimuli by modulating gene expression. TFs help plants balance the trade-off between stress tolerance growth, thus ensuring their long-term survival in challenging environments. Understanding mechanisms that define functionality of plant is paramount importance for unravelling intricate regulatory networks governing development, environmental plants. This review provides a comprehensive understanding these defining activity TFs. dynamic nature has practical implications modern molecular breeding programmes, as it insights into how manipulate expression optimize desired traits crops. Moreover, recent studies also report functional duality TFs, highlighting ability switch activation repression modes; this represents an important mechanism attuning Here we discuss what possible reasons dual are instructs cell fate decision during fine-tunes plants, enabling them adapt various challenges.
Language: Английский
Citations
6
Plant Physiology and Biochemistry, Journal Year: 2024, Volume and Issue: 214, P. 108950 - 108950
Published: July 18, 2024
Citations
5
Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 99 - 119
Published: Jan. 1, 2025
Language: Английский
Citations
0
Frontiers in Plant Science, Journal Year: 2025, Volume and Issue: 15
Published: Feb. 6, 2025
The challenges faced by today's agronomists, plant breeders, and their managers encompass adapting sustainably to climate variability while working with limited budgets. Besides, are dealing a multitude of issues different organizations on similar initiatives projects, leading lack sustainable impact smallholder farmers. To transform the current food systems as more resilient model efficient solutions needed deliver convey results. Challenges such logistics, labour, infrastructure, equity, must be addressed alongside increasingly unstable conditions which affect life cycle transboundary pathogens pests. In this context, transforming go far beyond just farmers breeders it requires substantial contributions from industry, global finances, transportation, energy, education, country developmental sectors including legislators. As result, holistic approach is essential for achieving sustain population anticipated reach 9.7 billion 2050 11.2 2100. 2021, nearly 193 million individuals were affected insecurity, 40 than in 2020. Meanwhile, digital world rapidly advancing economy estimated at about 20% gross domestic product, suggesting that technologies accessible even areas insecurity. Leveraging these can facilitate development climate-smart cultivars adapt effectively variation, meet consumer preferences, address human livestock nutritional needs. Most economically important traits crops controlled multiple loci often recessive alleles. Considering particularly Africa, continent has several agro-climatic zones, hence need adapted these. Therefore, targeting specific using modern tools offers precise approach. This review article aims how new provide better support
Language: Английский
Citations
0
Progress in molecular biology and translational science, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Language: Английский
Citations
0
International Journal of Innovations in Science Engineering and Management., Journal Year: 2025, Volume and Issue: unknown, P. 174 - 180
Published: Feb. 22, 2025
Evidence has been mounting over the last decade demonstrating crucial functions of ncRNAs, including miRNAs and long non-coding RNAs (lncRNAs), in cellular signalling networks gene regulation. These ncRNAs are highly expressed play a role regulating processes metastasis endothelial cell invasiveness. They facilitate crosstalk between interconnected signaling pathways, PTEN/PI3K/AKT/mTOR, by acting as linking molecules within signal circuits. In addition to expression conventional apical measures, studying provides better understanding both beneficial detrimental reactions external exposures. Additionally, miRNAs—which may be found extracellular intracellular environments, such biofluids—have become potential early precise molecular indicators tissue conditions. This review highlights regulatory their involvement homeostasis, biomarkers, shedding light on significance regulation, toxicological studies, precision medicine.
Language: Английский
Citations
0
Plant Cell Reports, Journal Year: 2025, Volume and Issue: 44(3)
Published: Feb. 27, 2025
Language: Английский
Citations
0
Plant Breeding, Journal Year: 2025, Volume and Issue: unknown
Published: March 19, 2025
ABSTRACT The challenge of feeding the world's growing population is impaired by declining arable land, water quality and erratic weather patterns due to climate change. Abiotic stresses such as drought, heat, salinity cold disrupt plant growth, reducing crop yields quality. Modern biotechnological tools including high‐throughput sequencing bioinformatics have enabled characterization stress responses through advanced “omics” technologies. Genomics, transcriptomics, proteomics, metabolomics epigenomics describe molecular mechanisms underlying tolerance. Integrating multi‐omics approaches provides a deeper understanding these mechanisms, addressing limitations single‐omics studies. combination data (genomics, proteomics metabolomics) identifies important biomarkers, regulatory networks genetic targets that enhance resilience. This information regarding plants crucial for genome‐assisted breeding (GAB) improve traits development climate‐resilient crops withstand environmental challenges. Therefore, researchers use pipelines productive crops, tolerance, solving global food security challenges caused change stressors. review discusses role omics technologies in describing explores how this applied resilience productivity, which leads improved crops. application combining develop next‐generation are capable thriving under adverse conditions, ensuring reliable safe supply future conditions.
Language: Английский
Citations
0
Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106633 - 106633
Published: April 1, 2025
Language: Английский
Citations
0