International Journal of Molecular Sciences,
Journal Year:
2023,
Volume and Issue:
24(6), P. 5465 - 5465
Published: March 13, 2023
Mitophagy/autophagy
plays
a
protective
role
in
various
forms
of
liver
damage,
by
renovating
cellular
metabolism
linking
to
sustain
homeostasis.
A
characterized
pathway
for
mitophagy
is
the
phosphatase
and
tensin
homolog
(PTEN)-induced
putative
kinase
1
(PINK1)/Parkin-dependent
signaling
pathway.
In
particular,
PINK1-mediated
could
play
an
indispensable
improving
metabolic
dysfunction-associated
fatty
disease
(MAFLD)
which
precede
steatohepatitis
(NASH),
fibrosis,
hepatocellular
carcinoma.
addition,
PI3K/AKT/mTOR
might
regulate
characteristics
homeostasis
including
energy
metabolism,
cell
proliferation,
and/or
protection.
Therefore,
targeting
with
alteration
or
PINK1/Parkin-dependent
eliminate
impaired
mitochondria
be
attractive
strategy
treatment
MAFLD.
efficacy
prebiotics
MAFLD
has
been
suggested
useful
via
modulation
PI3K/AKT/mTOR/AMPK
Additionally,
several
edible
phytochemicals
activate
improvement
mitochondrial
damages,
also
promising
option
treat
providing
Here,
potential
therapeutics
discussed
Tactics
viewpoint
prospective
probiotics
contribute
development
therapeutic
interventions.
Nutrients,
Journal Year:
2023,
Volume and Issue:
15(12), P. 2749 - 2749
Published: June 14, 2023
The
Western
diet
is
a
modern
dietary
pattern
characterized
by
high
intakes
of
pre-packaged
foods,
refined
grains,
red
meat,
processed
high-sugar
drinks,
candy,
sweets,
fried
conventionally
raised
animal
products,
high-fat
dairy
and
high-fructose
products.
present
review
aims
to
describe
the
effect
on
metabolism,
inflammation,
antioxidant
status;
impact
gut
microbiota
mitochondrial
fitness;
cardiovascular
health,
mental
cancer;
sanitary
cost
diet.
To
achieve
this
goal,
consensus
critical
was
conducted
using
primary
sources,
such
as
scientific
articles,
secondary
including
bibliographic
indexes,
databases,
web
pages.
Scopus,
Embase,
Science
Direct,
Sports
Discuss,
ResearchGate,
Web
were
used
complete
assignment.
MeSH-compliant
keywords
“Western
diet”,
“inflammation”,
“metabolic
health”,
fitness”,
“heart
disease”,
“cancer”,
“oxidative
stress”,
“mental
“metabolism”
used.
following
exclusion
criteria
applied:
(i)
studies
with
inappropriate
or
irrelevant
topics,
not
germane
review’s
focus;
(ii)
Ph.D.
dissertations,
proceedings
conferences,
unpublished
studies.
This
information
will
allow
for
better
comprehension
nutritional
behavior
its
an
individual’s
metabolism
well
national
systems.
Finally,
practical
applications
derived
from
are
made.
Journal of Immunology Research,
Journal Year:
2020,
Volume and Issue:
2020, P. 1 - 12
Published: July 31, 2020
Human
body
surfaces,
such
as
the
skin,
intestines,
and
respiratory
urogenital
tracts,
are
colonized
by
a
large
number
of
microorganisms,
including
bacteria,
fungi,
viruses,
with
gut
being
most
densely
extensively
organ.
The
microbiome
plays
an
essential
role
in
immune
system
development
tissue
homeostasis.
Gut
microbiota
dysbiosis
not
only
modulates
responses
gastrointestinal
(GI)
tract
but
also
impacts
immunity
distal
organs,
lung,
further
affecting
lung
health
diseases.
Here,
we
review
recent
evidence
correlations
underlying
mechanisms
relationship
between
common
diseases,
asthma,
chronic
obstructive
pulmonary
disease
(COPD),
cystic
fibrosis
(CF),
cancer,
infection,
probiotic
therapeutic
intervention
for
these
Nutrients,
Journal Year:
2021,
Volume and Issue:
13(8), P. 2877 - 2877
Published: Aug. 21, 2021
Celiac
disease
(CD)
is
a
chronic
autoimmune
disorder
of
the
small
intestine,
whose
only
effective
treatment
gluten-free
diet
(GFD).
It
characterized
by
atrophy
intestinal
villi
that
leads
to
altered
nutrient
absorption.
This
study
describes
nutritional
imbalances
which
may
be
found
in
adults
with
CD
following
GFD.
During
first
year
treatment,
deficiencies
will
overcome
as
mucosa
recovers.
Thus,
biochemical
data
show
this
progression,
together
decrease
symptoms.
In
contrast,
long
term,
when
strict
GFD
followed
and
mucosal
recovery
achieved,
analyzing
intake
makes
more
sense.
Macronutrient
consumption
its
low
complex
carbohydrate
fiber
intakes,
high
fat
(especially
SFA)
sugar
intakes.
profile
has
been
related
GFP
their
composition,
addition
unbalanced
dietary
habits.
The
most
notable
micronutrients
are
usually
those
iron,
calcium
magnesium
vitamin
D,
E
some
group
B.
necessary
follow
up
patients
promote
education
among
them,
since
it
could
help
not
achieve
gluten
free
but
also
balanced
diet.
Nutrients,
Journal Year:
2022,
Volume and Issue:
14(13), P. 2641 - 2641
Published: June 26, 2022
Throughout
history,
malnutrition
and
deficiency
diseases
have
been
a
problem
for
our
planet's
population.
A
balanced
diet
significantly
influences
everyone's
health,
fiber
intake
appears
to
play
more
important
role
than
previously
thought.
The
natural
dietary
fibers
are
category
of
carbohydrates
in
the
constitution
plants
that
not
completely
digested
human
intestine.
High-fiber
foods,
such
as
fruits,
vegetables
whole
grains,
consistently
highly
beneficial
health
effectively
reduced
risk
disease.
Although
mode
action
consumer
body
is
fully
understood,
nutritionists
professionals
unanimously
recognize
therapeutic
benefits.
This
paper
presents
consumption
different
countries,
metabolism
range
benefits
associated
with
intake.
In
addition,
influence
on
intestinal
microbiome,
metabolic
(obesity
diabetes),
neurological
aspects,
cardiovascular
diseases,
autoimmune
cancer
prevention
discussed.
Finally,
restrictions
excess
addressed,
which
can
cause
episodes
diarrhea
dehydration
increase
likelihood
bloating
flatulence
or
even
bowel
obstruction.
However,
extensive
studies
needed
regarding
composition
required
amount
relation
saprotrophic
microorganisms
from
enteral
level
various
pathologies
they
be
correlated.
Annual Review of Public Health,
Journal Year:
2021,
Volume and Issue:
42(1), P. 277 - 292
Published: April 1, 2021
The
human
microbiome
contributes
metabolic
functions,
protects
against
pathogens,
educates
the
immune
system,
and
through
these
basic
directly
or
indirectly,
affects
most
of
our
physiologic
functions.
Here,
we
consider
its
relationship
to
several
major
noncommunicable
conditions,
including
orodigestive
tract
cancers,
neurologic
diseases,
diabetes,
obesity.
We
also
highlight
scope
contextual
macroenvironmental
factors
(toxicological
chemical
environment,
built
socioeconomic
environment)
individual
microenvironmental
(smoking,
alcohol,
diet)
that
may
push
microbiota
toward
less
healthy
more
influencing
development
diseases.
Last,
current
uncertainties
challenges
in
study
environmental
influences
on
implications
for
understanding
disease,
suggesting
a
research
agenda
strengthen
scientific
evidence
base.
Comprehensive Reviews in Food Science and Food Safety,
Journal Year:
2024,
Volume and Issue:
23(3)
Published: April 29, 2024
Abstract
Red
berries
have
gained
popularity
as
functional
and
nutritious
food
due
to
their
health
benefits,
leading
increased
consumer
demand
higher
production,
totaling
over
11,000
ktons
for
strawberries,
raspberries,
blueberries
combined
in
2021.
Nutritionally,
present
high
levels
of
vitamin
C
(9.7–58.8
mg/100
g
dry
weight
[dw]),
folates
(6–24
µg/100
dw),
minerals
(96–228
dw).
Due
perishable
nature,
producers
utilized
alcoholic
fermentation
extend
shelf
life,
not
only
increasing
the
lifespan
red
but
also
attracting
consumers
through
production
novel
beverages.
Strawberry,
blueberry,
raspberry
wines
possess
low
alcohol
(5.5–11.1%
v/v),
acidity
(3.2–17.6
g/L),
interesting
bioactive
molecules
such
phenolic
compounds,
carotenoids,
polysaccharides,
melatonin.
Distillation
holds
tremendous
potential
reducing
waste
by
creating
berry
spirits
exceptional
quality.
Although
research
on
is
still
early
stages,
future
studies
should
focus
characterization.
By
incorporating
these
factors,
chain
would
become
more
sustainable,
profitable,
efficient
waste,
capitalizing
acceptance,
leveraging
natural
health‐promoting
characteristics
products.
Therefore,
this
review
aims
provide
a
comprehensive
overview
strawberry,
berries,
wines,
spirits,
with
chemical
composition
methods.
Nutrients,
Journal Year:
2019,
Volume and Issue:
11(10), P. 2381 - 2381
Published: Oct. 6, 2019
Noncommunicable
diseases
(NCDs)
are
considered
to
be
the
leading
cause
of
death
worldwide.
Inadequate
fruit
and
vegetable
intake
have
been
recognized
as
a
risk
factor
for
almost
all
NCDs
(type
2
diabetes
mellitus,
cancer,
cardiovascular
neurodegenerative
diseases).
The
main
aim
this
review
is
examine
possible
protective
effect
that
consumption
or
their
bioactive
compounds
may
on
development
such
atherosclerosis.
accumulated
evidence
effects
adequate
fruits
vegetables
in
some
cases,
lack
others,
summarized
present
review.
conclusion
well-designed,
large-scale,
long-term
studies
needed
truly
understand
role
Nutrients,
Journal Year:
2021,
Volume and Issue:
13(5), P. 1506 - 1506
Published: April 29, 2021
Irritable
Bowel
Syndrome
(IBS)
is
a
chronic
functional
gastrointestinal
disorder
characterized
by
abdominal
pain
associated
with
defecation
or
change
in
bowel
habits.
Gut
microbiota,
which
acts
as
real
organ
well-defined
functions,
mutualistic
relationship
the
host,
harvesting
additional
energy
and
nutrients
from
diet
protecting
host
pathogens;
specific
alterations
its
composition
seem
to
play
crucial
role
IBS
pathophysiology.
It
well
known
that
can
significantly
modulate
intestinal
microbiota
profile
but
it
less
how
different
nutritional
approach
effective
patients,
such
low-FODMAP
diet,
could
be
responsible
of
changes,
thus
influencing
presence
(GI)
symptoms.
The
aim
this
review
was
explore
effects
protocols
(e.g.,
traditional
advice,
gluten-free
etc.)
on
IBS-D
symptoms
variations
both
patients
healthy
subjects.
To
date,
an
ideal
protocol
does
not
exist
for
seems
consider
effect
approaches
better
define
efficient
strategy
manage
disorder.