The Effects of Exogenous Beta-Hydroxybutyrate Supplementation on Metrics of Safety and Health DOI Open Access
Matthew Stefan, Matthew Sharp,

Raad Gheith

et al.

International Journal of Nutrition and Food Sciences, Journal Year: 2020, Volume and Issue: 9(6), P. 154 - 154

Published: Jan. 1, 2020

The ketogenic diet is a high-fat, very low-carbohydrate, moderate-protein that will induce state of ketosis. Ketosis metabolic characterized by elevated ketone body production in response to the absence carbohydrates. Some drawbacks are it can be difficult adhere due its restrictive nature, and also cause some undesirable side effects like gastrointestinal distress increases apoB-lipoproteins. In order maximize benefit ketosis minimize effects, supplementing with exogenous beta-hydroxybutyrate may temporary without effects. present study, 22 healthy male female adults consumed 12.75 grams salts or maltodextrin placebo twice daily for 90 days. Comprehensive blood safety analysis, composition, bone densitometry, psychological immune surveys, pressure were administered at baseline, 30, 60, There no significant differences any measures collected, indicating had detrimental impact on fasting values such as electrolyte levels, glucose, hemoglobin A1c, complete count, density, well-being, status, pressure. We conclude safe well-tolerated adults.

Language: Английский

Calcium, magnesium, and vitamin D supplementations as complementary therapy for hypertensive patients: a systematic review and meta-analysis DOI Creative Commons
Samar A. Amer, Dina Essam Abo‐elnour, Abdallah Abbas

et al.

BMC Complementary Medicine and Therapies, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 5, 2025

Language: Английский

Citations

0
Point-of-care testing of hyponatremia and hypernatremia levels: An optoplasmonic biosensing approach DOI Creative Commons
Abdullah Mohammad Tanvirul Hoque, Abrar Islam, Firoz Haider

et al.

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(4), P. e0319559 - e0319559

Published: April 23, 2025

In the human body, sodium ion (Na + ) is principal extracellular cation and its imbalance in blood or lymph results either hyponatremia hypernatremia conditions. Any of these scenarios have fatal effects on a patient’s health over time. However, existing technologies limit quick point-of-care (POC) testing options. To overcome challenges associated with prompt diagnosis, we proposed photonic crystal fiber (PCF) based surface plasmon resonance (SPR) sensor for situ rapid Na levels samples. A unique PCF modified square lattice engineered to achieve propagation-controlled core that permits enhanced control wave guidance resulting improved sensing performance. Plasmonically active conducting indium tin oxide (ITO) used omit limitations arise from undesired oxidation time enable higher spectral tunability. The finite element method (FEM) perform numerical analysis performance all parameters are optimized ensure best outcome. structural asymmetry-induced birefringence enforced superior y-polarized response compared x-polarized mode sensor, where it proffers highest wavelength sensitivity 15,157 nm/RIU detection resolution 6.61 × 10 −6 RIU. Additionally, exhibits maximum amplitude 470 RIU −1 an outstanding figure merit (FOM) 171 . Due high resolution, infer will be promising POC alternative conventional serum electrolyte panels present medical practice.

Language: Английский

Citations

0
Estimated salt intake and risk of atrial fibrillation in a prospective community‐based cohort DOI Creative Commons
Jonas Wuopio, Marju Orho‐Melander, Johan Ärnlöv

et al.

Journal of Internal Medicine, Journal Year: 2020, Volume and Issue: 289(5), P. 700 - 708

Published: Nov. 19, 2020

Hypertension predisposes to atrial fibrillation (AF) - a major risk factor for ischaemic stroke. Since high dietary salt consumption is associated with hypertension, we investigated the association between urinary sodium excretion as marker intake and of new-onset AF in community-dwelling adults.The UK Biobank includes 40- 69-year-old British residents recruited 2006-2010. Participants were divided into sex-specific quintiles according 24-hour estimated based on spot samples Kawasaki equation. We excluded participants at baseline. Cox regression adjusted cardiovascular factors was used assess associations AF, using third quintile reference.A total 257 545 women 215 535 men included. During up 10 years' follow-up, 2221 3751 diagnosed AF. There tendency an increased lowest highest daily both men. In fully model, significant seen amongst (hazard ratio, HRQv1 , 1.20; 95% CI, 1.08-1.32, P < 0.001, HRQv5 1.15, 1.03-1.27, = 0.011).We found evidence U-shaped A suggestive J-shaped not statistically confirmed, but analyses likely underpowered. Our results suggest that above certain physiological minimum level progressively higher increasing

Language: Английский

Citations

21
The Effect of Exogenous Beta-Hydroxybutyrate Salt Supplementation on Metrics of Safety and Health in Adolescents DOI Open Access
Matthew Stefan, Matthew Sharp,

Raad Gheith

et al.

Nutrients, Journal Year: 2021, Volume and Issue: 13(3), P. 854 - 854

Published: March 5, 2021

The ketogenic diet is a high-fat, very low-carbohydrate, moderate-protein that will induce state of ketosis, but because its restrictive nature, it may be difficult to adhere to, especially in adolescents. Supplementing with exogenous beta-hydroxybutyrate salts temporary ketosis without any undesirable side effects, thereby promoting the benefits and minimizing adherence requirements diet. To date, supplementation healthy adolescents has not been explored. Therefore, purpose this study was examine safety salt adolescent population. In present study, 22 male female consumed 3.75 g or maltodextrin placebo twice daily for 90 days. Comprehensive blood analysis, bone densitometry, happiness emotional intelligence surveys, pressure were assessed at Pre, Day 45, 90. There no significant differences detected subjects supplementing salts, indicating had detrimental impact on fasting metrics, density, happiness, intelligence, pressure. We conclude safe well-tolerated by

Language: Английский

Citations

15
Nutrient pattern analysis of mineral based, simple sugar based, and fat based diets and risk of metabolic syndrome: a comparative nutrient panel DOI Creative Commons
Leila Nikniaz, Trias Mahmudiono, Saade Abdalkareem Jasim

et al.

BMC Endocrine Disorders, Journal Year: 2022, Volume and Issue: 22(1)

Published: March 2, 2022

Abstract Background Although there is growing evidence on the association between nutrient patterns and metabolic risk factors, very little known about relationship syndrome (MetS). The aim of this study was to examine associations with MetS among apparently healthy obese adults living in Tabriz, Iran. Methods Three hundred forty-seven (BMI ≥ 30 kg/m 2 ) aged 20–50 years were included cross-sectional study. Dietary intake 38 nutrients assessed by a validated semi-quantitative food frequency questionnaire (FFQ) 132 items. Nutrient determined using factor analysis. defined based guidelines National Cholesterol Education Program Adult Treatment Panel III (ATP III). Results major extracted: “Mineral pattern”, “Simple sugar pattern” “Fat pattern”. There no significant MetS, crude model even after adjusting for confounders. difference quartiles mineral pattern free mass (FFM), diastolic blood pressure (DBP), large Waist circumference (WC) Waist-to-hip ratio (WHR). In simple pattern, we observed SBP, DBP, triglyceride (TG) levels. addition, fat positively associated BMI, weight. Conclusions We did not observe any amongst adult's population. Whereas confirmed deleterious effect several our findings also showed that related healthier factors an Iranian These results should be approved future studies recognize causal adherence specific MetS.

Language: Английский

Citations

11
Diagnosis dan Terapi Non-farmakologis pada Hipertensi DOI Creative Commons
Pandit Bagus Tri Saputra, Ariikah Dyah Lamara, Mahendra Eko Saputra

et al.

Cermin Dunia Kedokteran, Journal Year: 2023, Volume and Issue: 50(6), P. 322 - 330

Published: May 31, 2023

Pada tahun 2019, hipertensi diderita oleh 1,28 milyar jiwa di seluruh dunia dan diperkirakan terus meningkat setiap tahun. Saat ini, masih menjadi salah satu penyebab utama morbiditas mortalitas global. Terdapat perubahan paradigma diagnosis lebih direkomendasikan dengan pemeriksaan tekanan darah luar klinik (out-of-office blood pressure measurement) berupa ambulatoar (PTDA) jika fasilitas memadai atau rumah (PTDR) pada terbatas. Manajemen pasien berfokus kontrol untuk meningkatkan kualitas hidup serta menurunkan angka kecacatan kematian terapi farmakologis non-farmakologis. Terapi non-farmakologis telah terbukti membantu mengontrol darah, mortalitas, baik individu maupun normal. In hypertension was suffered by 1.28 billion people worldwide and is expected to increase every year. Hypertension still one of the main causes global morbidity mortality. There a paradigm shift that more recommended out-of-office measurement. Blood measurements outside clinic can be done with ambulatory or home in limited facilities. Management hypertensive patients focuses on control pharmacological non-pharmacological method improve quality life, as well reduce Non-pharmacological approach has been proven optimize control, mortality both normal individuals.

Citations

6
Low Dietary Magnesium and Overweight/Obesity in a Mediterranean Population: A Detrimental Synergy for the Development of Hypertension. The SUN Project DOI Open Access
Ligia J. Domínguez, Alfredo Gea, Liz Ruiz-Estigarribia

et al.

Nutrients, Journal Year: 2020, Volume and Issue: 13(1), P. 125 - 125

Published: Dec. 31, 2020

Hypertension is the strongest independent modifiable risk factor for cardiovascular disease. We aimed to investigate association of magnesium intake with incident hypertension in a Mediterranean population, and potential modification this by body mass index BMI. assessed 14,057 participants SUN (Seguimiento Universidad de Navarra) prospective cohort (67.0% women) initially free hypertension. At baseline, validated 136-item food frequency questionnaire was administered. used Cox models adjusted multiple socio-demographic, anthropometric, lifestyle factors, prevalent conditions present at baseline. Among mean 9.6 years follow-up we observed 1406 cases medically diagnosed An inverse multivariable-adjusted progressively higher up 500 mg/d vs. < 200 mg/d, which greater among those BMI > 27 kg/m2. Lean >200 also had Adherence diet did not modify these associations. In conclusion, dietary independently associated developing cohort, stronger overweight/obese participants. Our results emphasize importance encouraging consumption magnesium-rich foods (vegetables, nuts, whole cereals, legumes) order prevent

Language: Английский

Citations

15
Serum Magnesium, Blood Pressure, and Risk of Hypertension and Chronic Kidney Disease Progression in the CRIC Study DOI Open Access
Simon Correa, Xavier Guerra, Sushrut S. Waikar

et al.

Hypertension, Journal Year: 2021, Volume and Issue: 78(6), P. 1771 - 1780

Published: Nov. 1, 2021

[Figure: see text].

Language: Английский

Citations

14
The effect of purple-black barberry (Berberis integerrima) on blood pressure in subjects with cardiovascular risk factors: a randomized controlled trial DOI
Hadi Emamat, Ali Zahedmehr, Sanaz Asadian

et al.

Journal of Ethnopharmacology, Journal Year: 2022, Volume and Issue: 289, P. 115097 - 115097

Published: Feb. 9, 2022

Language: Английский

Citations

9
The Importance of Nutrition in Hypertension DOI Open Access

Francesco Fantin,

Federica Macchi,

Anna Giani

et al.

Nutrients, Journal Year: 2019, Volume and Issue: 11(10), P. 2542 - 2542

Published: Oct. 21, 2019

Arterial hypertension (AH) is considered to be one of the most relevant cardiovascular risk factors, and its wide prevalence in all age ranges makes it necessary analyse possible causes treatments. In this special issue, nutritional interventions are examined either as or treatments AH. [...].

Language: Английский

Citations

12