Does the evidence support a relationship between higher levels of nut consumption, lower risk of depression, and better mood state in the general population? A systematic review

Nutrition Reviews, Journal Year: 2022, Volume and Issue: 80(10), P. 2076 - 2088

Published: March 10, 2022

Dietary patterns play a key role in mental health, depression, and mood state. However, the evidence concerning specific foods highly recommended for such as nuts, has not yet been synthesized.The objective of this review was to synthesize relationship between higher levels nut consumption, lower risk better state general population.The MEDLINE, Scopus, Cochrane Central, Web Science, PsycInfo databases were systematically searched from each database's inception March 2021.Randomized clinical trials (RCTs) observational studies exploring association level population included. The quality measured through Joanna Briggs Institute tool (cross-sectional studies), NIH Quality Assessment Tool (cohort Risk-of-Bias (RCTs). Preferred Reporting Items Systematic Reviews Meta-Analyses guidelines followed.A total 10 involving 66 418 individuals included, which 3 cross-sectional, cohort studies, 4 RCTs. In concerned with depression (n = 6 consumption associated 2 cross-sectional 1 study, while similar but nonsignificant found another two 4), study reported an significant improvement state, whereas (nonsignificant) associations increased negative feelings RCTs.Despite small number limitations related them, reverse causation bias, overall, available literature suggests that could be fewer depressive symptoms, population.PROSPERO registration no. CRD42021241070.

Language: Английский

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Effects of Almond Consumption on Selected Markers of Inflammation and Oxidative Stress: A Systematic Review and Meta-Analysis

Clinical Nutrition Research, Journal Year: 2025, Volume and Issue: 14(1), P. 78 - 78

Published: Jan. 1, 2025

This systematic review and meta-analysis aimed to evaluate the effectiveness of almond consumption on serum C-reactive protein (CRP) malondialdehyde (MDA) levels in individuals at risk cardiovascular disease (CVD). An electronic database search was performed PubMed, Web Science, Scopus, Cochrane Library from inception through October 2024. Summary effect size measurements were calculated using random effects model estimation reported as weighted mean differences (WMDs) along with 95% confidence intervals (CIs). A total 258 articles identified, 13 randomized controlled trials (RCTs) included meta-analysis. The eleven RCTs, which involved a 544 participants, indicated that almonds significantly reduced CRP (WMD, -0.28 mg/L; CI, -0.52, -0.04; p = 0.02). However, we found no significant benefit improving MDA levels, due limited number studies, examination conducted only qualitatively. study supports conclusion has favorable CVD factors. More high-quality are needed confirm these findings.

Language: Английский

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The effects of nuts intake on cognitive and executive function in obese children: a randomized clinical trial

Journal of Health Population and Nutrition, Journal Year: 2025, Volume and Issue: 44(1)

Published: March 12, 2025

Abstract Background Childhood obesity is a significant, worldwide challenge disrupting various body organs including the brain. Studies suggest that nuts, rich in nutritional compounds, can improve cognitive function. This study aimed to investigate effects of consuming nuts on improving and executive function obese children. Methods In this randomized parallel clinical trial, ninety 8 10-year-old girls with were divided into intervention (30 g nuts/daily) control groups (no nuts) for weeks. Furthermore, Wechsler Four (WISC-IV) questionnaire assessed children’s function, was by behavior rating inventory (BRIEF) parental questionnaire. Linear mixed-effect models done survey nut intake Results Forty people mean age 9 ± 0.7 years from each group cooperated end study. The showed significant improvement total score (differences: 23.1, 95% CI: 17.5, 28.7; P Time×Group < 0.001) BRIEF − 16.5, 29.4, 3.5; 0.05) compared group. Moreover, other components tests picture completion, concept, block design, object assembly, short-term memory, digit span, inhibition, displacement, initiation, organization significantly improved after 8th Conclusion These results underline potential consumption as dietary over an eight-week period, highlighting its role supporting brain health development

Language: Английский

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Does Medication Status Impact the Effectiveness of Nuts in Altering Blood Pressure and Lipids? A Systematic Review and Meta-Analysis

Nutrition Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Abstract Context Nut consumption is attributed to improvements in risk factors for cardiovascular disease (CVD), including high blood pressure (BP) and dyslipidemia. However, it unclear whether these effects are altered with concurrent treatment BP lipid-lowering medication. Objective We sought investigate the of whole tree nuts peanuts (collectively termed nuts) on lipids, medication use alters effects. Data Sources The MEDLINE, EMBASE, Scopus, Web Science databases were systematically searched through June 21, 2023, randomized controlled trials (RCTs) assessing nut and/or lipids. Extraction Random meta-analyses (mean difference, 95% confidence interval [CI]) conducted, subgroup analyses based reported participant or medication, medicated, unmedicated, unreported (ie, not specified), mixed included combined data from medicated unmedicated participants). A total 115 studies review, which 109 meta-analysed. Analysis significantly reduced triglycerides (TG), cholesterol, low-density lipoprotein very-low-density non–high-density apolipoprotein B, no effect high-density cholesterol pressure. Few conducted participants only (n = 1 lipid outcomes only), both mixed), by reported. Significant differences TG B observed between groups, resulting largest reductions participants. Strong heterogeneity was evidence publication bias. Conclusions Lipid-lowering, but BP-lowering benefits observed; however, few participants’ status. Future required determine if there additional diet patients disease. Systematic Review Registration PROSPERO registration code CRD42022296849.

Language: Английский

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Effect of Almond Consumption on Metabolic Risk Factors—Glucose Metabolism, Hyperinsulinemia, Selected Markers of Inflammation: A Randomized Controlled Trial in Adolescents and Young Adults

Frontiers in Nutrition, Journal Year: 2021, Volume and Issue: 8

Published: June 24, 2021

A large percentage of the Indian population has diabetes or is at risk pre-diabetes. Almond consumption shown benefits on cardiometabolic factors in adults. This study explored effect almond determinants metabolic dysfunction—blood glucose, lipids, insulin and selected inflammatory markers adolescents young adults aged 16–25 years from Mumbai city. randomized controlled trial was conducted for a period 90 days individuals with impaired levels fasting glucose between 100–125 mg/dL (5.6–6.9 mmol/L) 2-h post-glucose value 140–199 (7.8–11.0 and/or (≥15 mIU/ml)/stimulated (≥80 mIU/ml). Of 1,313 screened, 421 met inclusion criteria, which 275 consented to participate 219 completed trial. The registered Clinical Trials Registry India (CTRI) CTRI/2018/02/011927. almonds group ( n = 107) consumed 56 g daily, control 112) provided an iso-caloric cereal-pulse based snack. At baseline endline, blood insulin, HbA 1 c, LDL-c, HDL-c, total ox-cholesterol, triglycerides, hs-CRP, IL-6, TNF-α, adiponectin, leptin were measured HOMA-IR FG:FI ratios calculated. Dietary intakes assessed. anthropometric measurements, biochemical as well macronutrient did not differ significantly two groups baseline. decreased cholesterol LDL-c. Stimulated post-intervention both groups, but decrease greater group. Fasting reduced post intervention controls no change ratio TNF-α IL-6 group, while it increased Our results showed that HbA1c, LDL-c just 12 weeks these who developing diabetes. Almonds can be considered part food-based strategies preventing Trial Registration: ClinicalTrials.gov , identifier:

Language: Английский

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Effect of Nut Consumption on Blood Lipids: An updated Systematic Review and Meta-analysis of Randomized Controlled Trials

Nutrition Metabolism and Cardiovascular Diseases, Journal Year: 2024, Volume and Issue: unknown, P. 103771 - 103771

Published: Oct. 1, 2024

Language: Английский

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Role of fruit and vegetables in sustaining healthy cognitive function: evidence and issues

Proceedings of The Nutrition Society, Journal Year: 2023, Volume and Issue: 82(3), P. 305 - 314

Published: April 24, 2023

Modifiable lifestyle factors, such as improved nutrition, are crucial in maintaining cognitive health older age. Fruit and vegetables represent healthy sustainable sources of nutrients with the potential to prevent age-related decline. The aim this review is synthesise available evidence, from epidemiological randomised controlled trials (RCT), regarding role fruit sustaining function. Epidemiological studies combined vegetable intake suggest that increased consumption may sustain cognition later life. evidence appears be stronger for an association between cognition, particularly green leafy cruciferous vegetables. Specific benefits shown berries, citrus fruits, avocado nuts worthy further investigation relation cognition. Data RCT indicate differing aspects following berry cocoa peanuts, but data limited there a lack exploring effects There growing function, not always consistent limited. Issues previous research highlighted, strict exclusion criteria, absence baseline nutritional status consideration individual differences, which explain weaker findings RCT. Inclusion those most at risk decline recommended future nutrition research.

Language: Английский

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Nuts and Older Adults’ Health: A Narrative Review

International Journal of Environmental Research and Public Health, Journal Year: 2021, Volume and Issue: 18(4), P. 1848 - 1848

Published: Feb. 14, 2021

Although the beneficial effects of nuts on cardiometabolic diseases have been well established, little is known about age-related diseases. Given that share many biological pathways with diseases, it plausible diets rich in might be ameliorating conditions. The objective this review was to summarise findings from studies examined associations or nut consumption, either alone as part dietary pattern, three major factors—telomere length, sarcopenia, and cognitive function—in older adults. Overall, currently available evidence suggests particularly when consumed a healthy diet over prolonged period, associated positive outcomes such longer telomere reduced risk better cognition Future are interventional, long-term, adequately powered required draw definitive conclusions consumption order inform recommendations incorporate into habitual

Language: Английский

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The Effects of Almond Consumption on Inflammatory Biomarkers in Adults: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

Advances in Nutrition, Journal Year: 2021, Volume and Issue: 13(5), P. 1462 - 1475

Published: Dec. 23, 2021

Conflicting findings have been reported regarding the effects of almond consumption on inflammatory markers. This study aimed to summarize current literature determine whether almonds can affect A systematic search was carried out in PubMed, Scopus, and ISI Web Science up March 2021. Randomized clinical trials that compared with no were included. The outcomes interest changes circulating C-reactive protein (CRP), IL-6, TNF-α, intercellular adhesion molecule-1 (ICAM-1), vascular cell (VCAM-1) concentrations. random-effects model used find mean differences. In total, 18 847 participants eligible for analysis. Participants' ages ranged from 26.3 69.6 y. Combining 16 studies, significantly reduced serum concentrations CRP [weighted difference (WMD): -0.25 mg/L; 95% CI: -0.43, -0.06 I2 = 0.0%; P-heterogeneity 0.633]. However, beneficial effect intake only occurred at doses <60 g/d. Pooling 11 sizes, interventions decreased IL-6 (WMD: -0.11 pg/mL; -0.21, -0.01 19.9%; 0.254). subgroup analyses, nonsignificant unhealthy or those obesity. addition, had significant TNF-α -0.05 -0.11, 0.01 0.893; n 6), ICAM-1 6.39 ng/mL; -9.44, 22.22 66.6%; 0.006; 7), VCAM-1 -8.31 -35.32, 18.71 58.8%; 0.033; 6). conclusion, beneficially affects adults. it has ICAM-1, VCAM-1. More are needed inflammation.

Language: Английский

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The Effects of Tree Nut and Peanut Consumption on Energy Compensation and Energy Expenditure: A Systematic Review and Meta-Analysis

Advances in Nutrition, Journal Year: 2022, Volume and Issue: 14(1), P. 77 - 98

Published: Dec. 17, 2022

Nut consumption is not associated with a higher body weight, and potential energy-regulating mechanisms may include reduced subsequent energy intake increased EE. The aim of this study was to examine the effect tree nut peanut on intake, compensation, expenditure. PubMed, MEDLINE, CINAHL, Cochrane, Embase databases were searched from inception June 2, 2021. Human studies adults aged ≥18 y older included. Energy compensation restricted acute effects (intervention duration ≤24 h), whereas intervention limited for EE studies. Random meta-analyses conducted explore weighted mean differences in REE. Twenty-eight articles 27 (16 studies, 10 1 investigating both) 1121 participants included review, variety types addressed (almonds, Brazil nuts, cashews, chestnuts, hazelnuts, peanuts, pistachios, walnuts, mixed nuts). occurred after nut-containing loads (range: -280.5% +176.4%) degree varied depending form (whole chopped) how they consumed (alone within meal). identified nonsignificant increase REE (weighted difference: 28.6 kcal/d; 95% CI: -10.7, 67.8 kcal/d). This provided support as mechanism lack association between no evidence found an nuts. review registered at PROSPERO CRD42021252292.

Language: Английский

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