Life’s Essential 8: Updating and Enhancing the American Heart Association’s Construct of Cardiovascular Health: A Presidential Advisory From the American Heart Association

Circulation, Journal Year: 2022, Volume and Issue: 146(5)

Published: June 29, 2022

In 2010, the American Heart Association defined a novel construct of cardiovascular health to promote paradigm shift from focus solely on disease treatment one inclusive positive promotion and preservation across life course in populations individuals. Extensive subsequent evidence has provided insights into strengths limitations original approach defining quantifying health. response, convened writing group recommend enhancements updates. The definition quantification each metrics (Life’s Simple 7) were evaluated for responsiveness interindividual variation intraindividual change. New considered, age spectrum was expanded include entire course. foundational contexts social determinants psychological addressed as crucial factors optimizing preserving This presidential advisory introduces an enhanced assessing health: Life’s Essential 8. components 8 diet (updated), physical activity, nicotine exposure sleep (new), body mass index, blood lipids glucose pressure. Each metric new scoring algorithm ranging 0 100 points, allowing generation composite score (the unweighted average all components) that also varies points. Methods implementing assessment longitudinal monitoring are discussed, potential data sources tools widespread adoption policy, public health, clinical, institutional, community settings.

Language: Английский

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Dietary circadian rhythms and cardiovascular disease risk in the prospective NutriNet-Santé cohort

Nature Communications, Journal Year: 2023, Volume and Issue: 14(1)

Published: Dec. 14, 2023

Daily eating/fasting cycles synchronise circadian peripheral clocks, involved in the regulation of cardiovascular system. However, associations daily meal and fasting timing with disease (CVD) incidence remain unclear. We used data from 103,389 adults NutriNet-Santé study. Meal number eating occasions were estimated repeated 24 h dietary records. built multivariable Cox proportional-hazards models to examine their association risk CVD, coronary heart cerebrovascular disease. In this study, having a later first (later than 9AM compared earlier 8AM) last day 9PM 8PM) was associated higher outcomes, especially among women. Our results suggest potential benefit adopting patterns, coupling longer nighttime period an early meal, rather breakfast skipping, CVD prevention.

Language: Английский

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Effect of time-restricted feeding on body composition and cardio-metabolic risk in middle-aged women in Taiwan

Nutrition, Journal Year: 2021, Volume and Issue: 93, P. 111504 - 111504

Published: Sept. 30, 2021

Language: Английский

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Variability in Daily Eating Patterns and Eating Jetlag Are Associated With Worsened Cardiometabolic Risk Profiles in the American Heart Association Go Red for Women Strategically Focused Research Network

Journal of the American Heart Association, Journal Year: 2021, Volume and Issue: 10(18)

Published: Sept. 6, 2021

Background Sleep variability and social jetlag are associated with adverse cardiometabolic outcomes via circadian disruption. Variable eating patterns also lead to disruption, but associations health unknown. Methods Results Women (n=115, mean age: 33±12 years) completed a 1-week food record using the Automated Self-Administered 24-Hour Dietary Assessment Tool at baseline 1 year. Timing of first last occasions, nightly fasting duration, %kcal consumed after 5 pm (%kcal pm) 8 were estimated. Day-to-day was assessed from SD these variables. Eating defined as weekday-weekend differences in metrics. Multivariable-adjusted linear models examined cross-sectional longitudinal day-to-day metrics risk. Greater start time, related higher body mass index waist circumference (P<0.05). In analyses, 10% increase predicted increased (β, 0.52; 95% CI, 0.23-0.81) 1.73; 0.58-2.87); greater 0.25; 0.07-0.43). Every 30-minute duration diastolic blood pressure 0.95; 0.40-1.50); an equivalent systolic 0.58; 0.11-1.05) 0.45; 0.10-0.80). Per SD, there 2.98 mm Hg (95% 0.04-5.92) 2.37mm 0.19-4.55) increases pressure; 1.83; 0.30-3.36). For hemoglobin A1c, every end time 0.09% 0.03-0.15), 0.06% 0.001-0.12), 0.23% 0.07-0.39) increases, respectively. Conclusions adiposity worse glycemic control. Findings warrant confirmation population-based cohorts intervention studies.

Language: Английский

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Night eating in timing, frequency, and food quality and risks of all-cause, cancer, and diabetes mortality: findings from national health and nutrition examination survey

Nutrition and Diabetes, Journal Year: 2024, Volume and Issue: 14(1)

Published: Feb. 27, 2024

Abstract Objective To investigate the association of timing, frequency, and food quality night eating with all-cause, cancer, diabetes mortality. Methods This study included 41,744 participants from US National Health Nutrition Examination Survey (2002–2018). Night information was collected by 24-h dietary recall exposures were eating. Food assessed latent class analysis. The outcomes mortality, which identified Death Index International Classification Diseases 10th Revision. Adjusted hazard ratios [aHR] 95% confidence intervals [CI] computed Cox regression. Results During a median follow-up 8.7 years, 6066 deaths documented, including 1381 cancer 206 diabetes. Compared no (eating before 22:00), later timing associated higher risk all-cause mortality (each P -trend <0.05) rather than highest being 00:00–1:00 (aHR 1.38, CI 1.02–1.88) 23:00–00:00 2.31, 1.21–4.40), respectively. However, increased risks not observed for 22:00-23:00. Likewise, one time or over frequency < 0.05). That further in high-dietary-energy-density group (all-cause mortality: aHR 1.21 [95% 1.06–1.38]; 1.97 1.13–3.45]), but low-dietary-energy-density group. Finally, correlation analysis found positive associations glycohemoglobin, fasting glucose, OGTT. Conclusions mortality; however, reduction excess when 23:00 foods.

Language: Английский

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Chrononutrition and Cardiometabolic Health: An Overview of Epidemiological Evidence and Key Future Research Directions

Nutrients, Journal Year: 2024, Volume and Issue: 16(14), P. 2332 - 2332

Published: July 19, 2024

Chrononutrition is a rapidly evolving field of nutritional epidemiology that addresses the complex relationship between temporal eating patterns, circadian rhythms, and metabolic health, but most prior research has focused on cardiometabolic consequences time-restricted feeding intermittent fasting. The purpose this topical review to summarize epidemiological evidence from observational intervention studies regarding role chrononutrition metrics related timing regularity in health preservation cardiovascular disease prevention. Observational are limited due lack time-stamped diet data population-based studies. Findings cohort generally indicate breakfast skipping or later first occasion, lunch dinner, greater proportion caloric intake consumed evening associated with adverse outcomes, including higher risk for coronary heart disease, hypertension, type 2 diabetes, obesity, dyslipidemia, systemic inflammation. Randomized controlled trials also limited, as focus feeding. Overall, interventions shift patterns earlier day restrict tend have protective effects small sample sizes short follow-up notable limitations. Innovation dietary assessment approaches, develop low-cost validated tools acceptable participant burden reliably capture metrics, needed advancing evidence. Culturally responsive pragmatic sufficiently large representative samples understand impact fixed schedules health. Additional warranted modifiable determinants investigate context other dimensions (quantity, quality, food nutrition security) achieving equity, elucidate underlying physiological mechanisms.

Language: Английский

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Sleep and circadian rhythms: pillars of health—a Keystone Symposia report

Annals of the New York Academy of Sciences, Journal Year: 2021, Volume and Issue: 1506(1), P. 18 - 34

Published: Aug. 2, 2021

Abstract The human circadian system consists of the master clock in suprachiasmatic nuclei hypothalamus as well peripheral molecular clocks located organs throughout body. This plays a major role temporal organization biological and physiological processes, such body temperature, blood pressure, hormone secretion, gene expression, immune functions, which all manifest consistent diurnal patterns. Many facets modern life, work schedules, travel, social activities, can lead to sleep/wake eating schedules that are misaligned relative clock. misalignment disrupt impair psychological parameters may ultimately put people at higher risk for chronic diseases like cancer, cardiovascular disease, other metabolic disorders. Understanding mechanisms regulate sleep rhythms insights on behavioral interventions lower these diseases. On February 25, 2021, experts sleep, rhythms, chronobiology met virtually Keystone eSymposium “Sleep & Circadian Rhythms: Pillars Health” discuss latest research understanding bidirectional relationships between health disease.

Language: Английский

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A late eating midpoint is associated with increased risk of diabetic kidney disease: a cross-sectional study based on NHANES 2013–2020

Nutrition Journal, Journal Year: 2024, Volume and Issue: 23(1)

Published: March 23, 2024

Abstract Background Modifying diet is crucial for diabetes and complication management. Numerous studies have shown that adjusting eating habits to align with the circadian rhythm may positively affect metabolic health. However, midpoint, duration, their associations diabetic kidney disease (DKD) are poorly understood. Methods The National Health Nutrition Examination Survey (2013–2020) was examined information on dietary habits. From beginning ending times of each meal, we calculated midpoint duration. Urinary albumin-to-creatinine ratio (UACR) ≥ 30 mg/g and/or estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m 2 were specific diagnostic criteria DKD. Results In total, details 2194 subjects collected analysis. overall population divided into four subgroups based quartiles. prevalence DKD varied noticeably ( P = 0.037) across categories. When comparing in second fourth quartiles those first one, odds ratios (ORs) 1.31 (95% CI, 1.03 1.67) 1.33 1.05 1.70), respectively. And after controlling potential confounders, corresponding ORs 1.42 1.07 1.90) 1.39 1.04 1.85), Conclusions A strong correlation found between an earlier a reduced incidence Eating early day potentially improve renal outcomes patients diabetes.

Language: Английский

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Association of Nightly Fasting, Meal Frequency, and Skipping Meals with Metabolic Syndrome among Kuwaiti Adults

Nutrients, Journal Year: 2024, Volume and Issue: 16(7), P. 984 - 984

Published: March 28, 2024

Mounting evidence suggests that meal timing and frequency are associated with cardiometabolic health by influencing circadian rhythms. However, the is inconsistent limited, especially in non-Western cultures. This cross-sectional study aims to investigate association between temporal habits of dietary intake, such as nightly fasting duration frequency, metabolic syndrome among Kuwaiti adults. A 24-hour recall was used assess intake. Meal defined number daily eating episodes. The included a total 757 adults aged 20 years older. participants' mean age 37.8 ± 12.3 years. After adjusting for all confounders, higher found be lower prevalence (OR, 0.43; 95%CI, 0.19-0.96) elevated triglycerides men only 0.23; 0.09-0.60). No syndrome, but longer 0.19; 0.06-0.63). findings suggest having frequent meals durations may help decrease risk triglycerides.

Language: Английский

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Correlation of nighttime fasting duration with cognitive decline in older adults: a cross-sectional study based on NHANES 2011-2014

Published: March 30, 2025

Background: Cognitive dysfunction is a significant health challenge in the global elderly population, and its prevalence associated with multiple factors, including modifiable lifestyle factors. The relationship between nighttime fasting duration, potential factor, cognitive function has yet to be thoroughly investigated. Objective: To investigate association duration function. Methods: This cross-sectional study was based on data from National Health Nutrition Examination Survey (NHANES) 2011 2014. Weighted linear regression utilized examine function, additional curve fitting inflection point analysis conducted further elucidate this Results: There negative (Learn: β = -1.2, 95% CI: -1.98, -0.43, P 0.006; Recall: -1.1, -2.11, -0.09, 0.036; Animal Fluency: -4.49, -7.26, -1.72, 0.004; Digit Symbol Substitution Test: -12.66, -19.30, -6.01, 0.002). Subgroup analyses showed that correlation prevalent most subgroups. Curve revealed scores, but did not identify point. Conclusions: Longer times may decline, either as continuous or categorical variable.

Language: Английский

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