Dietary Vitamin B Complex: Orchestration in Human Nutrition throughout Life with Sex Differences DOI Open Access
Mennatallah A. Ali, Hala A. Hafez, Maher A. Kamel

et al.

Nutrients, Journal Year: 2022, Volume and Issue: 14(19), P. 3940 - 3940

Published: Sept. 22, 2022

The importance of B complex vitamins starts early in the human life cycle and continues across its different stages. At same time, numerous reports have emphasized critical role adequate intake. Most studies examined such issues concerning a specific vitamin or stage, with majority reporting effect either excess deficiency. Deep insight into orchestration eight requirements is reviewed cycle, beginning from fertility pregnancy reaching adulthood senility, emphasizing interactions among them underlying action mechanisms. sex also for each at stage to highlight daily and/or outcomes. Thiamine, riboflavin, niacin, pyridoxine, folic acid are crucial maternal fetal health. During infancy childhood, integrated physical psychological development that pivotal impact on one’s overall health adolescence adulthood. A higher intake elderly associated preventing some aging problems, especially those related inflammation. All supplementation should be carefully monitored avoid toxicity hypervitaminosis. More research invested studying individually nutritional disparities extensive attention paid cultural differences lifestyles.

Language: Английский

Diet, Nutrition, and Oral Health in Older Adults: A Review of the Literature DOI Creative Commons
Alice Kit Ying Chan, Yiu Cheung Tsang, Meng Jiang

et al.

Dentistry Journal, Journal Year: 2023, Volume and Issue: 11(9), P. 222 - 222

Published: Sept. 19, 2023

Diet, nutrition, and oral health are closely linked. Malnutrition is a challenging concern in older adults that associated with physical decline affecting their daily activities quality of life. The aim this review to provide an evidence-based summary the relationship between diet nutrition its implications. World Health Organization has declared healthy ageing priority work on ageing. American Dental Association confirmed bidirectional health. literature shows related diseases, including dental caries, periodontal tooth wear, even cancer. Insufficient nutritional intake poor dietary habits increase risk such as adults. On other hand, adults, conditions disease may induce pain, infection, loss, intake. Surveys have shown particular, those disadvantaged communities, suffered from deficiencies or imbalances In addition, current malnutrition frailty, hospitalization, mortality, morbidity. Good functional dentition essential maintain sufficient among reduce malnutrition. Therefore, integrating into general care service imperative improve status achieve

Language: Английский

Citations

26
Advancing dysphagia-oriented multi-ingredient meal development: Optimising hydrocolloid incorporation in 3D printed nutritious meals DOI Creative Commons
Sotiriοs Ι. Εkonomou, Miroslav Hadnađev, Aristea Gioxari

et al.

Food Hydrocolloids, Journal Year: 2023, Volume and Issue: 147, P. 109300 - 109300

Published: Sept. 27, 2023

Dysphagia (DP) is a growing health concern in today's ageing population, leading to high demand for DP-oriented food. 3D printing promising novel technology developing new attractive and appetising products. Therefore, we aimed develop 3D-printed shaped meal, serve as nutritious The texture was modified with the addition of different thickeners: 2.0% (w/w) k-carrageenan gum (KC) 1.0 or 1.5% guar (GG), xanthan (XG), locust bean (LBG), arabic (GA). Upon characterising mapping rheological behaviour involved extrusion-based printing, higher concentrations GG, XG, LBG GA were found significantly increase yield stress apparent viscosities ink formulations. In addition, colour attributes examined, while low population total viable bacteria (TVC) observed. formulations had fibre content, regulating bowel function glucose metabolism elderly. According International dysphagia diet standardisation initiative (IDDSI), KC/XG1 KC/LBG1 classified level 5 indicative minced moist diet, KC/GA1, KC/GA1.5, KC/XG1.5, KC/GG1.5 4, that can be bitten chewed if tongue control reduced. All demonstrated precision excellent self-supporting capability smooth surface easy extrude print complex samples. This study provides valuable insights into addressing by meal using printing.

Language: Английский

Citations

26
Lifestyle Trajectories Are Associated with Incidence of Cardiovascular Disease: Highlights from the ATTICA Epidemiological Cohort Study (2002–2022) DOI Creative Commons
Evangelia Damigou, Matina Kouvari, Christina Chrysohoou

et al.

Life, Journal Year: 2023, Volume and Issue: 13(5), P. 1142 - 1142

Published: May 8, 2023

The study aimed to assess the trajectories of lifestyle characteristics and their association with 20-year cardiovascular disease (CVD) incidence. In 2002, 3042 Greek adults (aged: 45 (12) years) free CVD were enrolled. 2022, follow-up was performed on 2169 participants; those, 1988 had complete data for CVD. incidence 3600 cases/10,000 individuals; man-to-woman ratio 1.25, peak difference in 35-45 age group (i.e., 2.1); however, a reversal trend observed age-groups 55-65 65-75, resumption an almost equal those >75 years. multi-adjusted analysis, age, sex, abnormal waist circumference, hypercholesterolemia, hypertension, diabetes positively associated risk, explaining 56% excess whereas additional 30% attributed trajectories; being physically active throughout life-course close Mediterranean diet protective, while continuous smoking detrimental against risk. adherence protected development even if not sustained, quitting or engaging physical activities during observation did offer any significant protection. A personalized approach that is cost-effective long-term sustained needed prevent burden.

Language: Английский

Citations

23
Improving geriatric outcomes through nutritional and immunonutritional strategies: Focus on surgical setting by a comprehensive evidence review DOI
Virginia Boccardi, Luigi Marano

Ageing Research Reviews, Journal Year: 2024, Volume and Issue: 96, P. 102272 - 102272

Published: March 15, 2024

Language: Английский

Citations

13
Sarcopenia and poor nutritional status in older adults DOI Creative Commons

Laura Calcaterra,

Gabor Abellán van Kan, Zara Steinmeyer

et al.

Clinical Nutrition, Journal Year: 2024, Volume and Issue: 43(3), P. 701 - 707

Published: Jan. 30, 2024

The association between sarcopenia and malnutrition has been poorly studied in the older population. purpose of this study is to address sarcopenia, according different validated definitions, nutritional status a large population community-dwelling adults. Observational, cross-sectional Geriatric Frailty Clinic (GFC) for Assessment Prevention Disability, held by "Gérontopôle" Toulouse University Hospital. Patients aged above 65 years who benefitted from Dual X-ray Densitometry (DXA) during their assessment at GFC June 5th 2013 January 28th 2020 were included. Sarcopenia was defined proposed definitions. Mini Nutritional (MNA) used stratify status, identify patients with poor (at risk or malnourished, MNA <24). Multiple logistic regression analyses performed each definition adjusted confounders. Among 938 DXA data, total 809 (86.2 %) subjects included analysis (mean age 81.8 ± 6.9 years, 527 females (65.1 %)). Prevalence ranged 12.6 % 44.9 %, various Overall 244 (30.2 had (MNA-score <24), Baumgartner Newman definitions both associated low MNA-scores (OR = 4.69, CI 3.15-6.98 OR 2.30, 1.55-3.14, respectively), EWGSOP2 "confirmed sarcopenia" also 3.68, 2.30-5.89), as well lean mass cut-off 5.22 3.52-7.73). Both FNIH "probable not malnutrition. In study, prevalence A score under 24, almost all This reinforces concept that are strictly related. When facing daily clinical practice, body composition should be assessed intervention tailored these results order prevent onset late-life disability.

Language: Английский

Citations

12
Inflamm-ageing: how cytokines and nutrition shape the trajectory of ageing DOI Creative Commons
Francesca Coperchini,

Alessia Greco,

Marsida Teliti

et al.

Cytokine & Growth Factor Reviews, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 1, 2024

Population ageing is increasing in prevalence most developed countries. Ageing the decline of functional properties at cellular, tissue, and organ level. Biochemical changes that occur all organisms experience biological are referred to as "Hallmarks ageing". Inflammation a common denominator hallmarks ageing, being mechanistically involved age-related health consequences. Inflamm-ageing refers inflammatory immune systems which somehow drive process towards healthy or unhealthy ageing. Current evidences, support that, reversing pro-inflammatory status inflamm-ageing, able modulate associated with increased levels molecules (e.g. cytokines, chemokines), ultimately producing chronic low-grade state typically observed older individuals. It commonly accepted balance between pro- anti-inflammatory cytokines/chemokines one factors determining whether occurs. Malnutrition nutritional imbalances, highly prevalent elderly, playing role driving immunoactive molecules. In particular, malnutrition major risk factor for sarcopenia, phenomenon characterized by loss muscle mass, often basis frailty. Given close relationship there also evidence link Indeed, cytokine/chemokine elderly patients were demonstrated. The demonstration specific cytokines play modulating appetite nutrient sensing taste reception, provided further existence nutrition shaping trajectory present review will overview current supporting circulating chemokines inflammation, malnutrition.

Language: Английский

Citations

11
Sarcopenia as the Mobility Phenotype of Aging: Clinical Implications DOI Creative Commons
Sunghwan Ji, Hee‐Won Jung, Ji Yeon Baek

et al.

Journal of Bone Metabolism, Journal Year: 2024, Volume and Issue: 31(1), P. 1 - 12

Published: Feb. 29, 2024

Sarcopenia, which is characterized by an age-related decline in muscle mass and function, poses significant challenges to geriatric care. Its definition has evolved from muscle-specific criteria include mass, physical performance, recognizing sarcopenia as a frailty. Sarcopenia associated with adverse outcomes, including mortality, falls, fractures, cognitive decline, admission long-term care facilities. Neuromechanical factors, protein-energy balance, protein synthesis-breakdown mechanisms contribute its pathophysiology. The identification of involves screening tests comprehensive assessment strength, function. Clinical approaches aligned the principles prioritize patient-centered This aids identifying issues related activities daily living, cognition, mood, nutrition, social support, alongside other aspects. general approach factors underlying loss functional patients includes managing chronic diseases evaluating administered medications, interventions exercise well evolving pharmacological options. Ongoing research targeting pathways, such myostatin-activin mimetics, holds promise for interventions. In summary, requires multifaceted approach, acknowledging complex etiology tailoring individual patient needs.

Language: Английский

Citations

8
How Diet and Lifestyle Can Fine-Tune Gut Microbiomes for Healthy Aging DOI
María Tamayo, Maitane Olivares, Patricia Ruas‐Madiedo

et al.

Annual Review of Food Science and Technology, Journal Year: 2024, Volume and Issue: 15(1), P. 283 - 305

Published: June 28, 2024

Many physical, social, and psychological changes occur during aging that raise the risk of developing chronic diseases, frailty, dependency. These adversely affect gut microbiota, a phenomenon known as microbe-aging. Those microbiota alterations are, in turn, associated with development age-related diseases. The is highly responsive to lifestyle dietary changes, displaying flexibility also provides anactionable tool by which healthy can be promoted. This review covers, firstly, main socioeconomic factors modify composition function or unhealthy and, secondly, advances being made defining promoting aging, including microbiome-informed artificial intelligence tools, personalized patterns, food probiotic systems.

Language: Английский

Citations

8
Hemoglobin, albumin, lymphocyte and platelet (HALP) score for predicting early and late mortality in elderly patients with proximal femur fractures DOI Creative Commons
Abdussamed Vural, Turgut Dolanbay,

Hilal Yağar

et al.

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(1), P. e0313842 - e0313842

Published: Jan. 9, 2025

Background Predicting mortality and morbidity poses a significant challenge to physicians, leading the development of various scoring systems. Among these, hemoglobin, albumin, lymphocyte platelet (HALP) score evaluates patient’s nutritional immune status. The primary aim this study was determine predictive effect HALP on 30-day 1-year in elderly patients with proximal femoral fractures (PFFs). Materials methods Patient demographic, clinical, laboratory, prognostic data were obtained. categorized into two groups: survival nonsurvival at endpoints. calculated compared among groups other biomarkers such as C-reactive protein (CRP) albumin ratio (CAR). ability predict between groups. risk also optimal threshold. Results had statistically endpoints lower non-surviving group. cut-off value (17.975) superb, sensitivity 0.66 specificity 0.86 (AUC: 0.826, 95% CI: 0.784–0.868). In addition, power differentiate survivors non-survivors more than that indices (p < 0.001). Patients ≤ 17.975 11.794 times ≥ (Odds ratio: 11.794, CI [7.194–19.338], p Conclusion results indicate demonstrates efficacy utility predicting PFFs.

Language: Английский

Citations

1
High Geriatric Nutritional Risk Index Risk as a Predictor of Postoperative Complications and Early Mortality in Older Adult Patients Undergoing Pancreatoduodenectomy for Periampullary Malignancies DOI Open Access
Ming-Hung Wang, Chien-Yu Chen, Yu‐Hung Lin

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(2), P. 655 - 655

Published: Jan. 20, 2025

Introduction: Pancreaticoduodenectomy (PD) is a major surgery associated with significant morbidity and mortality, especially in older adult patients. Malnutrition common complication these patients linked to poorer outcomes. This study aimed investigate the associations between preoperative nutritional status using Geriatric Nutritional Risk Index (GNRI) postoperative outcomes who underwent PD. Methods: A retrospective cohort was conducted on 363 The GNRI calculated based serum albumin levels body mass index. ≤ 82, 83 ≤98, > 98 were classified as severely malnourished, moderately/mildly no malnourishment, respectively. Perioperative data, including demographics, comorbidities, complications, collected. Univariate multivariate analyses performed assess such length of hospital stay, overall survival. Results: Patients higher more likely experience Clavien–Dindo grade ≥ 3b complications (42.1% vs. 22.0% 14.1%; p = 0.027) pulmonary (26.3% 11.9% 4.2%; 0.016). These also stayed at for longer duration (17.0% 16.0% 11.0%; < 0.001). Multivariate analysis confirmed that an independent predictor adverse outcomes, even after adjusting other confounding factors. Conclusions: Our findings highlight importance assessment undergoing low scores are increased risk prolonged recovery. results underscore need targeted interventions regular monitoring Future studies should focus improve

Language: Английский

Citations

1