Characteristics of the gut microbiome of Swiss elite athletes with a spinal cord injury: An exploratory study

Journal of Spinal Cord Medicine, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 9

Published: Jan. 11, 2024

Objectives To illustrate and explore associations between the gut microbiome spinal cord injury (SCI) characteristics, physical training, dietary intake, body composition, blood biomarkers of elite Swiss athletes.

Language: Английский

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The feasibility of a randomized controlled crossover trial to assess the effect of probiotic and prebiotic supplementation on the health of elite wheelchair athletes

Pilot and Feasibility Studies, Journal Year: 2023, Volume and Issue: 9(1)

Published: June 15, 2023

Gastrointestinal (GI) problems represent a health burden in Para athletes and can ultimately reduce athletic performance. This study aimed to evaluate the feasibility of randomized controlled crossover trial (RCCT) assessing effects probiotic prebiotic supplementation on Swiss elite wheelchair athletes.The RCCT was conducted between March 2021 October 2021. Athletes were receive either daily (3 g preparation, including eight bacterial strains), or (5 oat bran) first. After first phase (4 weeks), washout period weeks) second followed. Data collected at four visits (every 4 included 3-day training nutrition diaries, Quality Life Index (GIQLI) questionnaire, stool samples, fasting blood samples. The assessed criteria such as recruitment rate, retention success data collection, adherence protocol, willingness participate, safety.This pilot met majority predefined minimum requirements for criteria. Out 43 invited athletes, 14 (33%) consented (mean (standard deviation) age: 34 (9) years, females, 11 with spinal cord injury). desired sample size not reached, but achieved rate modest, especially considering population studied. All participating completed study. With exception one missing two successfully all visits. Most adhered intake protocol least 80% days, both probiotics (n = 12, 86%) prebiotics 11, 79%). Ten (71%) would be willing participate similar again. No serious adverse events occurred.Despite limited number Switzerland modest implementation is feasible. this provide essential information design subsequent which will include larger cohort physically active users.Swiss Ethics Committee Northwest/Central (EKNZ), 2020-02337).gov, NCT04659408.

Language: Английский

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Gut–Lung Microbiota Interaction in COPD Patients: A Literature Review

Medicina, Journal Year: 2022, Volume and Issue: 58(12), P. 1760 - 1760

Published: Nov. 30, 2022

Respiratory diseases are one of the leading causes death in world, which is why a lot attention has been recently paid to studying possible mechanisms for development pulmonary and assessing impact on their course. The microbiota plays an important role these processes influences functionality human immune system. Thus, alterations normal microflora contribute reduction immunity more severe course diseases. In this review, we summarized information about gut lung interactions with particular influence chronic obstructive disease (COPD).

Language: Английский

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Systematic review of factors influencing human digestive microbiota in healthy adults and interactions between them

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: March 13, 2024

Abstract Introduction: Human digestive microbiota is affected by a wide variety of different factors. The objective this study was to perform systematic review that gathers and updates the information available about factors affect human in healthy adults older than 19 years. It also reviewed way recover data these every know which are considered if some type interaction between them studied. Methods: We systematically searched MEDLINE, Web Science, Scielo, PROSPERO, Cochrane databases for relevant articles on microbiota. Two authors independently eligibility extraction. Articles were classified based studied factor upon one following categories: diet, habits, environment, or chemical exposure. Results: 41 included questionnaire addressing affecting collected from questionnaires used studies analyzed presence exposition chemicals. Analysis indicates assessment risk often partial focused specific aspect (diet, chemicals). In addition, there not being assessed (type fermentation meals, UP foods consumption, vitamin D administration, snacking, intermittent fasting, number daily intakes, sport practiced, living with pets working another animals, transportation used, place work, home cleaning treatments radiotherapy, immune suppressants, corticosteroids, anovulatory). Discussion: Little known impact combined possible exposure). Further encouraged evaluate more broadly may influence diversity their interactions.

Language: Английский

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The Synergistic Impact of Probiotic Supplementation and High-intensity Interval Training on Dyslipidemia and the Liver Longevity Genes in Ovariectomized Rats

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: April 2, 2024

Objective: This study aimed to explore the synergistic impact of supplementing with local probiotic consumption and engaging in high-intensity interval training (HIIT) on liver health. The focus was particularly targeting revitalization genes Cisd2 Hnf4α improving dyslipidemia. Methods: In this study, forty ovariectomized (OVX) Wistar rats were divided into five groups: one control, sham surgery, four groups receiving either 1 ml synthesized or engaged HIIT at 90-95% VO2 max for eight weeks finally co-treatment exercise probiotics. Following interventions, protein expressions measured using Western blotting, assessments lipid profiles conducted colorimetric analysis enzyme-linked immunosorbent assay. Results: Western blot demonstrated a notable increase Hnf4a levels following co-administration probiotics compared OVX + Vehicle group (P=0.001). Furthermore, revealed significant decrease weight, WC, visceral fat, BMI, TG, TC, LDL-C concentrations, coupled increased HDL-C (P = 0.001). Conclusion: Our indicates efficacy combined lactobacillus treatment elevating longevity markers mitigating factors associated obesity

Language: Английский

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Relationship of nutrition and physical activity with gut microbiota

Food and Health, Journal Year: 2024, Volume and Issue: 10(2), P. 160 - 168

Published: Jan. 1, 2024

Diet and physical activities are factors that affect the diversity composition of intestinal microbiota. Human health is closely related to balanced relationship between gut microbiota, activity nutrition. It has been reported microbiota also varies in individuals fed with different diets such as high-carbohydrate diets, high-protein high-fat vegetarian/vegan diet, gluten-free diet mediterranean diet. Depending on type food consumed, dietary components carbohydrates, proteins, fats, phytochemicals vitamins have potential balance positively or negatively. a supports digestion absorption nutrients well exercise performance thus contributes metabolic activities. However, just can change depending intensity exercise. moderate causes positive changes while long strenuous negative effects

Language: Английский

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The diversity of factors influencing human digestive microbiota in healthy adults and their interaction: A scoping review

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: July 25, 2024

Background / objectives Human digestive microbiota is affected by a wide variety of different factors. The objective this study was to perform scoping review that gathers and updates the information available about factors affect human in healthy adults. It also reviewed if other are considered some type interaction between them studied. We searched MEDLINE, Web Science, Scielo, PROSPERO, Cochrane databases. Two authors independently eligibility data extraction. Articles were classified based on main factor studied upon one following categories: diet, habits, environment, or chemical exposure. Results literature search provided total 73 studies met inclusion criteria. presence influence exposition chemicals registered. Analysis indicates assessment risk often focused specific aspect (diet, chemicals) up now not sufficiently investigated. In addition, there situations probably relevant being assessed (snacking, intermittent fasting, sport practiced, living with pets working animals, transportation daily used, home cleaning treatments radiotherapy, immune suppressants, corticosteroids). Conclusions Little known impact combined possible exposure) dysbiosis microbiota. Further encouraged evaluate more broadly interactions may diversity All act together every day our health.

Language: Английский

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Gut Microbiota Modulation

Journal of Student Research, Journal Year: 2024, Volume and Issue: 13(1)

Published: Feb. 29, 2024

This review explores the transformative potential of gut microbiota modulation in sports medicine, where convergence advanced technology, rigorous training, and injury management aims to mitigate sports-related injuries. Athletes high-intensity demand exceptional physical prowess, adhering grueling training regimens for peak fitness levels. However, pursuit athletic excellence often leads exhaustive stress sport-specific Personalized medicine has emerged as an adaptive discipline, utilizing diverse technologies methods deliver customized medical care enhance performance. The microbiota, a complex microbial community gastrointestinal system, significantly influences energy production, digestion, immune defense. Similar personalized every individual is unique, shaped by genetics, diet, lifestyle, environment. Recent research underscores profound impact on performance, recovery, overall health. consolidates current knowledge regarding revealing its revolutionize athlete performance enhancement. uniqueness our lies considering interplay between health relatively unexplored area. study highlights prospect tailoring nutritional based unique profile individual, marking new era medicine. Addressing significant literature gap, this emphasizes importance medicine—a paradigm shift poised expedite reduce risk.

Language: Английский

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Relation entre microbiote gastrique et cancer de l’estomac

La Presse Médicale Formation, Journal Year: 2024, Volume and Issue: 5(6), P. 385 - 390

Published: Oct. 9, 2024

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Major evidence of clinical studies on the triad gut microbiota, ubiquinone and physical exercise: a systematic review

International Journal of Nutrology, Journal Year: 2023, Volume and Issue: 16(2)

Published: March 17, 2023

Introduction: In the scenario of sports practices, human gut microbiota is currently focus convergent interest in many diseases and performance. Sports performance studies have also shown interesting promising results. Supplementation with certain antioxidants such as ubiquinone [Coenzyme Q10 (CoQ10)] important for physically active individuals to speed recovery from fatigue prevent exercise damage. Objective: It was demonstrate influence on athletes. Methods: The systematic review rules PRISMA Platform were followed. research carried out September November 2022 Scopus, PubMed, Science Direct, Scielo, Google Scholar databases. quality based GRADE instrument risk bias analyzed according Cochrane instrument. Results Conclusion: 104 articles found. A total 54 evaluated 27 included this review. Considering tool bias, overall assessment resulted 13 a high that did not meet GRADE. Most showed homogeneity their results, X 2 =97.2% >50%. composition activity are influenced by different factors, diet physical activity. Cumulative data indicate bacteria sensitive modulation activity, demonstrated using models training hypoactivity. antioxidant Coenzyme accelerate damage caused exercise, addition optimizing improving Clinical concerning patients low plasma concentrations Q10.

Language: Английский

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