Logistic Regression Model: The Effect of Endogenous Magnesium Level on the Concentration of Magnesium Drugs in a Bioequivalence Study DOI
Н. Н. Еременко, Е. В. Ших, G. V. Rаmenskаya

et al.

Pharmaceutical Chemistry Journal, Journal Year: 2023, Volume and Issue: 57(5), P. 621 - 626

Published: Aug. 1, 2023

Language: Английский

Nutritional Support for Alcoholic Liver Disease DOI Open Access
Tomoko Tadokoro, Asahiro Morishita, Takashi Himoto

et al.

Nutrients, Journal Year: 2023, Volume and Issue: 15(6), P. 1360 - 1360

Published: March 10, 2023

Malnutrition is a common finding in alcohol use disorders and associated with the prognosis of patients alcoholic liver disease (ALD). These also frequently show deficiencies vitamins trace elements, increasing likelihood anemia altered cognitive status. The etiology malnutrition ALD multifactorial complex includes inadequate dietary intake, abnormal absorption digestion, increased skeletal visceral protein catabolism, interactions between ethanol lipid metabolism. Most nutritional measures derive from general chronic recommendations. Recently, many have been diagnosed metabolic syndrome, which requires individualized treatment via therapy to avoid overnutrition. As progresses cirrhosis, it complicated by protein–energy sarcopenia. Nutritional important management ascites hepatic encephalopathy as failure progresses. purpose review summarize therapies for ALD.

Language: Английский

Citations

24
Selective adsorption of the activator diammonium hydrogen phosphate in the reverse flotation separation of brucite and dolomite DOI
Xiufeng Gong, Jin Yao, Bin Yang

et al.

Powder Technology, Journal Year: 2023, Volume and Issue: 429, P. 118923 - 118923

Published: Aug. 18, 2023

Language: Английский

Citations

15
Association of Dietary Selenium Intake with Type 2 Diabetes in Middle-Aged and Older Adults in China DOI Open Access
Fangyuan Li,

Xi Hong,

Huijun Wang

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(14), P. 2367 - 2367

Published: July 21, 2024

The relationship between distinct dietary selenium intake and type 2 diabetes (T2D) is still a topic of uncertainty. This study examined the T2D risk among middle-aged older Chinese adults. Dietary was assessed through three 24 h recalls, using data from China Health Nutrition Survey. To investigate potential dose-response pattern likelihood developing T2D, we employed both restricted cubic spline analysis Cox proportional hazards model as our analytical tools. A cohort 5970 participants aged ≥ 50 years followed for an average 5.44 years. results revealed V-shaped correlation risk, with lowest observed at approximately 45 µg/day. Below this level, decreased increasing intake, while increased 100 No significant association found beyond These findings suggest that low high consumption may increase highlighting importance maintaining balanced prevention.

Language: Английский

Citations

5
Effects of Various Heavy Metal Exposures on Insulin Resistance in Non-diabetic Populations: Interpretability Analysis from Machine Learning Modeling Perspective DOI
Jun Liu, Xingyu Li, Peng Zhu

et al.

Biological Trace Element Research, Journal Year: 2024, Volume and Issue: 202(12), P. 5438 - 5452

Published: Feb. 26, 2024

Language: Английский

Citations

4
Serum Magnesium Level as a Point of Reference for Categorising the Glycaemic Quality in Type 2 Diabetes Mellitus DOI Creative Commons

Shafia Sharmin Moutushi,

Roshia Parveen,

Malabika Sarker

et al.

Advances in Human Biology, Journal Year: 2025, Volume and Issue: unknown

Published: March 8, 2025

Abstract Introduction: Magnesium (Mg 2+ ) is a critical micromineral and one of the utmost essential intracellular cations. It works as co-factor in different metabolic backlash carbohydrates. A considerable number studies have found tie-up between low serum Mg levels uncontrolled blood sugar type 2 diabetes mellitus (T2DM). Materials Methods: This traverse study comprised 107 diagnosed cases T2DM, including from Holy Family Red Crescent Medical College Hospital outpatient department, Dhaka, Bangladesh. Fasting was collected, fasting sugar, concentration haemoglobin A1C (HbA1c) (HbA1C test that shows what your average [glucose] level over past 2–3 months) were measured. The participants grouped into categories because their glycaemic control levels, where HbA1c < 7% had clinically reasonable glucose homoeostasis, T2DM with > 7 inadequate management level. linear regression model examined association HbA1c. Results: Among individuals’ hypomagnesaemia (<1.8 mg/dL) observed 34.6%% individuals. subjects, 86% poor (HbA1c 7%). When comparison made showed significantly higher patients hypomagnesaemia. We also 1 mg/dL decreased increased by 133% ( P = 0.005). Conclusion: Hypomagnesaemia closely analogous to control. reflects disadvantageous among patients. So, correcting may alleviate status

Language: Английский

Citations

0
Hypomagnesemia induces impaired glucose metabolism and insulin resistance in patients with Gitelman syndrome DOI

Yu Xin,

Yaqi Yin, Li Zhu

et al.

Diabetes Research and Clinical Practice, Journal Year: 2025, Volume and Issue: unknown, P. 112160 - 112160

Published: March 1, 2025

Language: Английский

Citations

0
Association between Serum Magnesium and all-cause mortality in patients with Sepsis-associated liver injury: A Cohort Study DOI

Xiaona Yi,

Xiao-Ya Yang,

Dongkai Li

et al.

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: May 6, 2025

Abstract Background Serum magnesium is critical for cellular function and impaired homeostasis associated with increased mortality in critically ill patients. However, its role sepsis-associated liver injury (SALI) remains unclear. This study aims to elucidate the association between serum all-cause patients SALI. Methods Data this retrospective cohort were obtained from Medical Information Mart Intensive Care IV (MIMIC-IV), which included initial levels of diagnosed SALI admitted ICU. Multivariable Cox regression analysis, Kaplan-Meier survival curves, restricted cubic spline (RCS) used assess on admission ICU in-hospital Results A total 1367 enrolled an rate 34.97%. Multivariate analysis showed that increasing at admission, HR 1.28 (1.06–1.53, p 0.009). RCS suggests a nonlinear Conclusions found high independently SALI, showing association. Nevertheless, confirmation requires further validation through large-scale prospective studies.

Language: Английский

Citations

0
Gender differences in the association between sleep duration and diabetes in Chinese adults DOI Creative Commons

Haiyan Yu,

Xiaodong Zhang,

Haishan Wei

et al.

Frontiers in Endocrinology, Journal Year: 2025, Volume and Issue: 16

Published: May 20, 2025

Background and objectives There is growing evidence that sleep duration associated with future risk of new-onset diabetes mellitus. However, discussions gender differences have yielded inconsistent results. The aim this longitudinal study was to explore issue in a large group Chinese adult population. Methods 13,142 participants (6,366 men 6,776 women) without at baseline from China Health Nutrition Survey (CHNS) were included. They participated least two rounds the CHNS during 2004-2015. Multivariate Cox proportional hazards regression models used calculate hazard ratios (HRs) 95% confidence intervals (CIs) for diabetes. In addition, non-linearity relation analyzed by restricted cubic splines (RCS). Results During follow-up period 2004 2015, there 222 new cases (5.34 per 1000 person-years) 234 women (5.26 had newly developed women, U-shaped association between lowest individuals sleeping 8-9h day after adjusting covariates. Compared reference (8-9h/day), HRs who slept &lt;6h/day, &gt;10h/day 2.47 (1.22-4.99), 2.65(1.14-6.16) adjustment Among &lt;60 years old, compared subjects &lt;7 hours day, those 7-&lt;8h/day (HR = 0.73, 95%CI 0.42-1.24), 8-&lt;9h/day 0.57, 0.33-0.99), ≥9 h/day 0.35, CI 0.14-0.90) lower all potential confounders ( p -trend &lt; 0.001). No significant relationship observed over 60 age. Conclusions approximately 8–9h/day. For men, decreased significantly increasing only among years. effect on older not statistically significant.

Language: Английский

Citations

0
The prognostic value of serum Mg2+ concentration in patients with heart failure and type 2 diabetes mellitus: a retrospective cohort study DOI
Yangyang Jiang, Jingshu Zhang, Zhichao Jiang

et al.

Endocrine, Journal Year: 2025, Volume and Issue: unknown

Published: May 21, 2025

Language: Английский

Citations

0
Genome-wide association study of serum magnesium in type 2 diabetes DOI Creative Commons
Lynette J. Oost, Roderick C. Slieker, Marieke T. Blom

et al.

Genes & Nutrition, Journal Year: 2024, Volume and Issue: 19(1)

Published: Jan. 26, 2024

Abstract People with type 2 diabetes have a tenfold higher prevalence of hypomagnesemia, which is suggested to be caused by low dietary magnesium intake, medication use, and genetics. This study aims identify the genetic loci that influence serum concentration in 3466 people diabetes. The GWAS models were adjusted for age, sex, eGFR, HbA1c. Associated traits identified using publicly available data from GTEx consortium, human kidney eQTL atlas, Open database. genome-wide significant locus TAF3 ( p = 2.9 × 10 −9 ) In skeletal muscle, located demonstrate an link ATP5F1C , gene involved formation Mg 2+ -ATP. Serum levels associated MUC1/TRIM46 −7 SHROOM3 4.0 ), SLC22A7 1.0 −6 at nominal significance, combination suggesting they are possible candidates renal failure. Several agreement previous genomic studies P meta 6.9 −29 Q 0.81) −27 0.04) general population. conclusion, concentrations variability around regions TAF3, MUC1/TRIM46,

Language: Английский

Citations

3