Effects of Active Ingredients in Alcoholic Beverages and Their De-Alcoholized Counterparts on High-Fat Diet Bees: A Comparative Study DOI Creative Commons

Guanghe Fan,

Xiaofei Wang,

Cuicui Gao

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(8), P. 1693 - 1693

Published: April 9, 2024

The mechanisms by which alcohol, alcoholic beverages, and their de-alcoholized derivatives affect animal physiology, metabolism, gut microbiota have not yet been clarified. polyphenol, monosaccharide, amino acid, organic acid contents of four common beverages (Chinese Baijiu, beer, Chinese Huangjiu, wine) counterparts were analyzed. research further explored how these non-alcoholic versions obesity microbiota, using a high-fat diet bee model created with 2% palm oil (PO). results showed that wine, possessing the highest polyphenol content, its form, particularly when diluted five-fold (WDX5), markedly improved health markers PO-fed bees, including weight, triglycerides, total cholesterol levels in blood lymphocytes. WDX5 treatment notably increased presence beneficial microbes such as Bartonella, Gilliamella, Bifidobacterium, while decreasing Bombilactobacillus abundance. Moreover, was found to closely resemble sucrose water (SUC) terms microbial function, significantly boosting short-chain fatty acids, lipopolysaccharide associated enzymatic pathways, thereby favorably affecting metabolic regulation stability bees.

Language: Английский

Regulating role of Pleurotus ostreatus insoluble dietary fiber in high fat diet induced obesity in rats based on proteomics and metabolomics analyses DOI
Jinmei Wang,

Qingchun Zhao,

Hui Liu

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 136857 - 136857

Published: Oct. 1, 2024

Language: Английский

Citations

1
Pleurotus abieticola Polysaccharide Alleviates Hyperlipidemia Symptoms via Inhibition of Nuclear Factor-κB/Signal Transducer and Activator of Transcription 3-Mediated Inflammatory Responses DOI Open Access
Yongfeng Zhang, Yingjie Lin, Keyi Wu

et al.

Nutrients, Journal Year: 2023, Volume and Issue: 15(23), P. 4904 - 4904

Published: Nov. 23, 2023

Hyperlipidemia (HLP) is a metabolic syndrome induced by obesity, which has been widely recognized as significant threat to human health. Pleurotus abieticola, an edible lignin-degrading fungus, remains relatively understudied in terms of its bioactivity and medicinal properties. In this study, the lipid-lowering effect abieticola polysaccharide (PAPS1) was systematically explored high-fat diet (HFD)-induced HLP mice. The findings demonstrated that administration PAPS1 significantly inhibited bodyweight gain, ameliorated blood glucose lipid levels, reduced fat accumulation, mitigated hepatic injury addition, capability increase levels three distinct fecal metabolites while simultaneously reducing eight other According biological detection, level reactive oxygen species (ROS) pro-inflammatory factors, such tumor necrosis factor (TNF)-α interleukin (IL)-1β, -6, -17A, -22, -23, increased expression anti-inflammatory IL-10. Combined with proteomics, Western blot immunohistochemistry analysis showed exerted suppressive effects on inflammation oxidative damage inhibiting nuclear factor-κB (NF-κB)/signal transducer activator transcription 3 (STAT3) signaling pathway These offer evidence supporting effectiveness therapeutic agent through targeting chronic inflammation.

Language: Английский

Citations

3
Mechanisms Involved in Edible Mushrooms’ Health Beneficial Effects DOI
Diana Pelinescu, Ileana Stoica

Published: Jan. 1, 2023

Despite the mushrooms' long application history, only in last century, more data regarding their nutritional qualities and beneficial effects have been available. The progress scientific fields such as biology, chemistry, medicine, pharmacology allowed obtaining on mechanisms involved effects. main linked to presence of different biologically active compounds are antioxidant activity, antimicrobial immunomodulatory effect, anticancer antitumor activity. Although much has obtained until now, study mushrooms is still far from being completed because many wild not yet studied, number biological huge, fully elucidated.

Language: Английский

Citations

2
Sanjin Paishi Decoction improves the imbalance of gut microbiota and regulates MAPK signaling pathway to inhibit calcium oxalate stones in rats DOI
Ying Tian, Juan Zhao, Lan Chen

et al.

International Urology and Nephrology, Journal Year: 2023, Volume and Issue: 55(10), P. 2421 - 2429

Published: June 27, 2023

Language: Английский

Citations

2
Effects of Active Ingredients in Alcoholic Beverages and Their De-Alcoholized Counterparts on High-Fat Diet Bees: A Comparative Study DOI Creative Commons

Guanghe Fan,

Xiaofei Wang,

Cuicui Gao

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(8), P. 1693 - 1693

Published: April 9, 2024

The mechanisms by which alcohol, alcoholic beverages, and their de-alcoholized derivatives affect animal physiology, metabolism, gut microbiota have not yet been clarified. polyphenol, monosaccharide, amino acid, organic acid contents of four common beverages (Chinese Baijiu, beer, Chinese Huangjiu, wine) counterparts were analyzed. research further explored how these non-alcoholic versions obesity microbiota, using a high-fat diet bee model created with 2% palm oil (PO). results showed that wine, possessing the highest polyphenol content, its form, particularly when diluted five-fold (WDX5), markedly improved health markers PO-fed bees, including weight, triglycerides, total cholesterol levels in blood lymphocytes. WDX5 treatment notably increased presence beneficial microbes such as Bartonella, Gilliamella, Bifidobacterium, while decreasing Bombilactobacillus abundance. Moreover, was found to closely resemble sucrose water (SUC) terms microbial function, significantly boosting short-chain fatty acids, lipopolysaccharide associated enzymatic pathways, thereby favorably affecting metabolic regulation stability bees.

Language: Английский

Citations

0