Sleep patterns and cardiovascular disease risk in US participants: a comprehensive analysis

Frontiers in Neuroscience, Journal Year: 2025, Volume and Issue: 18

Published: Jan. 9, 2025

To evaluate the association between sleep-related factors, including sleep duration, self-reported disturbances, and diagnosed disorders, risk of cardiovascular disease (CVD) in US participants. The data this study from National Health Nutrition Examination Survey (NHANES) conducted 2007 2014. Sleep factors were assessed using a standardized questionnaire, overall scores calculated on scale 0 to 3. participants classified into three pattern groups: poor (overall score ≤ 1), intermediate = 2), healthy 3). CVD was defined based questionnaire responses. Logistic regression models used investigate CVD. Among 21,115 participants, 2,245 (10.6%) with Participants patterns had significantly higher (OR 1.82, 95% CI: 1.52-2.16, p < 0.001). Self-reported trouble sleeping 1.53, 1.32-1.78, 0.001), disorder 2.09, 1.75-2.50, 0.001) related an increased However, no such observed for either short 1.12, 0.95-1.33, 0.174) or long durations 1.14, 0.90-1.45, 0.266). Our also suggested interaction age (P 0.002). This highlights significant

Language: Английский

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Association between lymphocyte to high-density lipoprotein cholesterol ratio and insulin resistance and metabolic syndrome in US adults: results from NHANES 2007–2018

Lipids in Health and Disease, Journal Year: 2025, Volume and Issue: 24(1)

Published: Jan. 10, 2025

Insulin resistance (IR) and metabolic syndrome (MetS) are significant global health challenges that increase the risk of various chronic diseases. The lymphocyte-to-high-density lipoprotein cholesterol ratio (LHR) has emerged as a novel inflammatory marker. present study focused on evaluating association between LHR both IR MetS. We analyzed data from 14,779 adults aged ≥ 20 years National Health Nutrition Examination Survey (2007–2018). To investigate relationship MetS, we conducted multivariable logistic regression analyses. reliability results was validated through stratified sensitivity Furthermore, thoroughly examined possible nonlinear associations by implementing restricted cubic spline in conjunction with threshold effect analysis. Compared to lowest quartile, individuals highest quartile indicated significantly increased prevalence (odds = 3.72, 95% confidence intervals: 3.01–4.59) MetS 11.38, 8.85–14.63) fully adjusted models. Subgroup analyses demonstrated remained consistent across all subgroups, no interaction observed. However, more pronounced female participants. Restricted revealed identified inflection points at 0.055 for these non-linear relationships. An elevated positively associated indicating its promising role early screening disease prevention biological monitoring.

Language: Английский

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Age-dependent interaction between serum zinc and triglyceride-glucose index among American adults: National Health and Nutrition Examination Survey

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 11

Published: Jan. 13, 2025

Introduction Zinc plays a crucial role in glucose metabolism. The association between serum zinc and insulin resistance has recently been investigated as well, but the findings are inconsistent. triglyceride-glucose index (TyG) is frequently utilized epidemiological research to assess resistance. levels TyG not yet explored. Therefore, we designed this cross-sectional study relationship adults using data from National Health Nutrition Examination Survey (NHANES). Methods A analysis was performed on 1,610 aged ≥20 years who participated (NHANES) 2011–2016. participants were stratified by age, differences log-transformed quartiles further evaluated age groups &lt;60 ≥60 multivariable linear regression with an interaction test. Additionally, restricted cubic spline (RCS) model employed examine dose-response relationships TyG. Results In study, significant observed individuals those when transformed into categorical variable ( P -value for likelihood ratio test = 0.017). fully adjusted analyses, group demonstrated J-shaped nonlinear pattern nonlinearity 0.014), inflection point at ~1.94 μg/dL. While group, it exhibited inverted-L shaped &lt; 0.001 *** ). Conclusion There United States, potentially influencing association. Further prospective studies needed offer additional evidence insights these findings.

Language: Английский

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Association of dietary niacin intake with osteoporosis in the postmenopausal women in the US: NHANES 2007–2018

Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 12

Published: Feb. 5, 2025

Background Elderly individuals with inadequate vitamin B level are at increased risk of degenerative conditions, notably cardiovascular disorders, cognitive impairments, and osteoporosis. The relationship between niacin (vitamin B3) consumption osteoporosis remains a subject debate. This study aimed to clarify the dietary intake incidence in postmenopausal women aged ≥50 years. Methods In this study, we gathered details on participants’ bone mineral density, status, intake, several other critical variables. Multivariate logistic regression models were constructed determine association Restricted cubic splines employed further assess linearity explore shape dose-response associations. Additionally, performed stratified interaction analyses illustrate stability observed relationships across different subgroups. Results After adjusting for all covariates, there was significant inverse (OR = 0.87; 95% CI: 0.77–0.97; p 0.016). A negative (nonlinear: 0.672). While revealed some differences risk, these not statistically significant. Conclusion Dietary exhibited an correlation significantly reduced by 13% every 10 mg/day increase daily among women.

Language: Английский

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L-shaped relationship between dietary niacin intake and hearing loss in United States adults: National health and nutrition examination survey

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(2), P. e0319386 - e0319386

Published: Feb. 25, 2025

Hearing loss poses a significant threat to human health, with its prevalence increasing annually. Niacin (vitamin B3) is an essential B vitamin that plays crucial role in energy metabolism and cellular repair the body. Additionally, it exerts protective influence on cells of inner ear. A correlation between dietary niacin hearing has been reported; however, results remain controversial, requiring further investigation. This study aimed examine potential association intake United States (U.S.) adults, providing reference for preventive management loss. In this cross-sectional study, data derived from National Health Nutrition Survey U.S. adults aged 20 69 years, spanning 2011–2012 2015–2016 cycles, were used. Logistic regression, restricted cubic spline models, subgroup analyses, sensitivity analyses used assess stability results. total 7675 participants included, whom 772 (10.1%) exhibited low-frequency (LFHL), 1165 (15.2%) had speech-frequency (SFHL), 2816 (36.7%) high-frequency (HFHL). final model, adjusted odds ratios LFHL, SFHL, HFHL Q2 (16.97–23.40 mg/day) compared those Q1 (≤16.96 0.73 (0.57–0.92), 0.76 (0.61–0.94), 0.80 (0.67–0.96), respectively. The relationship (HL) was illustrated via L-shaped curve inflection point approximately 23.26 mg/day. HL individuals less than mg/day as follows: 0.950 (0.917–0.984) 0.951 (0.921–0.982) 0.965 (0.939–0.992) HFHL. To summarize, “L”-shaped occurrence estimated at revealed present study.

Language: Английский

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