Journal of Agricultural and Food Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 3, 2024
The
global
prevalence
of
type
2
diabetes
mellitus
has
become
a
major
public
health
challenge.
Dietary
intervention
is
cornerstone
management,
yet
the
optimal
macronutrient
composition
remains
an
open
question.
In
this
study,
mice
were
fed
western
(W)
diet,
moderately
high-fat
(MHF)
high-protein-high-carbohydrate
(HPHC)
or
high-protein-low-carbohydrate
(HPLC)
diet
for
22
weeks
to
compare
effects
different
dietary
patterns
on
glucose
homeostasis.
Our
results
showed
that
MHF
under
consistent
nutrient
quality,
was
most
beneficial
metabolism.
reduced
two
key
inducers
diabetes─lipid
accumulation
and
inflammation.
Downregulation
intestinal
CD36
induced
by
loss
JACC Advances,
Journal Year:
2024,
Volume and Issue:
3(6), P. 100924 - 100924
Published: March 25, 2024
Low-carbohydrate
high-fat
(LCHF)
diets
have
attracted
interest
for
a
variety
of
conditions.
In
some
individuals,
these
trigger
hypercholesterolemia.
There
are
limited
data
on
their
effects
cardiovascular
disease
risk.
To
investigate
the
association
between
LCHF
dietary
patterns,
lipid
levels
and
incident
major
adverse
events
(MACE).
cohort
from
UK
Biobank,
participants
with
≥
one
24-hour
questionnaire
were
identified.
A
diet
was
defined
as
<100g
and/or
<25%
total
daily
energy
(TDE)
carbohydrates/day
>45%
TDE
fat,
standard
(SD)
not
meeting
criteria.
Each
case
age-
sex-matched
1:4
to
SD
individuals.
From
2034
8136
identified
participants,
305
1220
individuals
completed
an
enrollment
assessment
concurrently
lipids
collection.
this
cohort,
low-density
lipoprotein-cholesterol
(LDL-C)
apolipoprotein
B
(apoB)
significantly
increased
in
vs
group
(p<0.001).
11.1%
6.2%
demonstrated
severe
hypercholesterolemia
(LDL-C
>5
mmol/L,
p<0.001).
After
11.8
years,
9.8%
4.3%
experienced
MACE
This
difference
remained
significant
after
adjustment
risk
factors
(HR
2.18,
95%
CI
1.39-3.43,
Individuals
elevated
LDL-C
polygenic
score
had
highest
concentrations
diet.
Similar
changes
associations
confirmed
entire
≥2
surveys.
Consumption
associated
apoB,
MACE.
Nutrients,
Journal Year:
2025,
Volume and Issue:
17(1), P. 165 - 165
Published: Jan. 1, 2025
Background:
Diet
and
inflammation
are
both
associated
with
hypertension.
We
aimed
to
investigate
the
relationship
between
dietary
index
(DII),
patterns,
risk
of
hypertension
among
Xinjiang
residents.
Methods:
A
total
930
residents
aged
20–80
from
Shihezi
Tumushuk
were
selected
as
participants
using
a
stratified
whole
cluster
random
sampling
method.
General
demographic
information,
data,
physical
examination
results
collected
DII
scores
calculated.
Restricted
cubic
spline
was
used
analyze
dose–response
LASSO
regression
screen
factors
Factor
analysis
extract
patterns.
Finally,
logistic
modeling
association
DII,
Results:
The
linearly
positively
developing
Logistic
showed
that
prevalence
2.23
(95%
CI:
1.53,
3.23)
3.29
2.26,
4.79)
in
T2
T3
groups,
respectively,
compared
T1
group.
Riboflavin
folate
In
vegetable–egg
pattern,
reduced
by
33%,
39%,
37%
groups
Q2,
Q3,
Q4,
group
Q1
(Q2:
OR
=
0.67,
95%
0.45,
0.99;
Q3:
0.61,
0.41,
0.92;
Q4:
0.63,
0.42,
0.96).
Conclusions:
higher
score,
Xinjiang.
addition,
patterns
can
reduce
Therefore,
local
should
be
scientifically
instructed
increase
their
intake
vegetables
eggs.
Journal of Food Biochemistry,
Journal Year:
2025,
Volume and Issue:
2025(1)
Published: Jan. 1, 2025
Arsenic
is
an
internationally
recognized
groundwater
pollutant.
exposure
causes
a
number
of
negative
consequences
on
the
human
body,
including
upsurge
oxidant.
Nutrition
significant
susceptibility
factor
for
arsenic
toxicity
through
various
conceivable
pathways.
The
rise
high‐fat
diets
in
numerous
countries
leads
to
increase
chronic,
noncommunicable
diseases.
This
research
examined
how
Nauclea
latifolia
could
reduce
oxidative
stress,
inflammation,
and
distortion
liver
kidneys
Wistar
rats
exposed
arsenic.
Five
groups
five
each
were
treated
daily
6
weeks.
Rats
fed
only
with
diet
exhibited
considerable
elevations
proinflammatory
markers,
urea,
creatinine,
enzymes,
alongside
decreases
SOD,
CAT,
GSH
levels.
Treatment
silymarin
N.
root
extract
prevented
stress
elevated
enzyme
activity
kidney
function
biomarkers.
subjected
suffered
damage
histology
kidney.
However,
treatment
extracts
protected
damage.
roots
may
attenuate
toxic
high
fat
renal
system
by
lowering
reactive
oxygen
molecules
improving
function.
Thus,
serve
as
natural
agent
prevent
hepatorenal
toxicity.
Nutrients,
Journal Year:
2025,
Volume and Issue:
17(9), P. 1475 - 1475
Published: April 27, 2025
Ketogenic
diets
(KDs)
have
gained
attention
for
their
potential
to
promote
weight
loss
and
metabolic
improvements.
However,
data
on
long-term
body
composition
changes
adherence
rates
in
real-world
settings
remain
limited.
This
study
aimed
assess
the
effects
of
a
personalized
ketogenic
dietary
program
anthropometric
parameters
over
9-month
period
evaluate
across
time.
A
total
491
adults
participated
longitudinal
intervention
involving
structured
nutrition
plan
with
follow-up
at
3,
6,
9
months.
Body
weight,
fat
mass
(FM),
skeletal
muscle
(SMM),
other
metrics
were
measured
each
visit.
Significant
reductions
(-12.6
kg)
(-10.3
observed
after
3
months
(p
<
0.001),
minimal
6
partial
regain
by
Month
9.
SMM
remained
relatively
stable
throughout
study.
Retention
dropped
substantially
months,
dropping
from
487
115
participants
41
Despite
this,
who
completed
maintained
significant
well-formulated
diet
may
rapid
while
preserving
lean
short
term.
poses
challenges.
Strategies
enhance
sustainability
retention
are
essential
maximizing
benefits
KDs
clinical
practice.
BMC Biology,
Journal Year:
2024,
Volume and Issue:
22(1)
Published: Sept. 16, 2024
The
importance
of
parental
diet
in
relation
to
eventual
offspring
health
is
increasing
prominence
due
the
increased
frequency
parents
reproductive
age
consuming
poor
diets.
Whilst
maternal
and
outcome
have
been
studied
some
detail,
paternal
impacts
are
not
as
well
understood.
A
father's
nutritional
status
has
shown
negative
consequences
on
foetal
growth
development
ultimately
impact
long-term
adult
offspring.
In
this
study,
we
examined
sperm-
seminal
vesicle
fluid-mediated
mechanisms
preimplantation
embryo
alterations
response
sub-optimal
