Tritordeum Bulel and Aucan: Promising Cultivars to Improve Health DOI Open Access
Salvatore De,

Antonella Venezia,

Luigia Di Stasio

et al.

Published: Dec. 11, 2023

Tritordeum is an amphiploides species resulting from the hybridization between durum wheat (T. durum) and wild barley (H. chilense). This new cereal considered a natural crop as it obtained by traditional breeding techniques. Given its appreciable organoleptic characteristics, agronomic features, presence of interesting components, good technological properties, tritordeum promising interest for development health-oriented foods. In this study, we evaluated two registered cultivars, Bulel Aucan. T. (Provenzal) was employed positive control. The extracted proteins were digested gastric /pancreatic proteases their biological effects on Caco-2 differentiated transwell inserts determined. Changes in cell viability, monolayer permeability, organization F-actin microfilaments, ER stress, triggered protein-digested samples (DPs) inspected. Our results showed that exposure to Provenzal-DPs promptly disrupted tight junction barrier. Conversely, Aucan-DPs did not enhance permeability; whereas, Bulel-DPs exerted only slight effects. Provental-DPs-induced toxicity also confirmed changes viability deep reorganization enterocyte cytoskeleton. contrast, affect cytoskeleton structure. Overall, our findings suggest both cultivars could be potential candidates mitigating flour.

Language: Английский

Tritordeum Bulel and Aucan: Promising Cultivars to Improve Health DOI Open Access
Salvatore De,

Antonella Venezia,

Luigia Di Stasio

et al.

Published: Dec. 11, 2023

Tritordeum is an amphiploides species resulting from the hybridization between durum wheat (T. durum) and wild barley (H. chilense). This new cereal considered a natural crop as it obtained by traditional breeding techniques. Given its appreciable organoleptic characteristics, agronomic features, presence of interesting components, good technological properties, tritordeum promising interest for development health-oriented foods. In this study, we evaluated two registered cultivars, Bulel Aucan. T. (Provenzal) was employed positive control. The extracted proteins were digested gastric /pancreatic proteases their biological effects on Caco-2 differentiated transwell inserts determined. Changes in cell viability, monolayer permeability, organization F-actin microfilaments, ER stress, triggered protein-digested samples (DPs) inspected. Our results showed that exposure to Provenzal-DPs promptly disrupted tight junction barrier. Conversely, Aucan-DPs did not enhance permeability; whereas, Bulel-DPs exerted only slight effects. Provental-DPs-induced toxicity also confirmed changes viability deep reorganization enterocyte cytoskeleton. contrast, affect cytoskeleton structure. Overall, our findings suggest both cultivars could be potential candidates mitigating flour.

Language: Английский

Citations

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