Medical supervised duodenal-enteral feeding for the treatment of overweight and obesity: MESUDEFT DOI Creative Commons
Isaac Kuzmar,

José Rafael Consuegra,

Tiffany Rangel

et al.

Nutrición Hospitalaria, Journal Year: 2023, Volume and Issue: unknown

Published: Jan. 1, 2023

Background: the development of specialised nutritional support techniques allows maintenance an adequate supply nutrients in those patients whom oral feeding is not possible or insuffi cient relation to their requirements, trying improve quality life, especially with chronic diseases.Methods: single-center clinical study carried out a clinical-nutritional center consisting medically supervised nasogastric-duodenal tube treatment for overweight, obesity and increased body fat percentage requiring it by means duodeno-enteral feeding, expecting losses more than 10 %.Results: twenty-nine completed protocol (20.4 % male 79.6 female) mean age 38 years (SD: 12.4); 87.2 kg 18.5) weight; 37.9 4.8) iFat%; 32.4 5.4) iMean mass index (BMI); 100 cm 16.0) waist; 113.6 10.4) hip; 33.8 3.9) upper arm circumference; 65.5 7.5) thigh 9.7 iVisceral index; 22.9 days 13.9) treatment.A MESUDEFT infl uences weight loss, visceral loss decreased arm, hip circumferences (p < 0.05) (i: initial).Conclusions: shown be effective alternative as sole adjunct prior bariatric surgery overweight minimum BMI at completion 3-6 months follow-up.

Language: Английский

Preoperative Nutrition in Bariatric Surgery: A Narrative Review on Enhancing Surgical Success and Patient Outcomes DOI Open Access
Daniel Simancas‐Racines, Evelyn Frías-Toral, Martín Campuzano-Donoso

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(3), P. 566 - 566

Published: Feb. 2, 2025

Bariatric surgery has become the preferred treatment for individuals with morbid obesity. Nutrition is key in optimizing surgical outcomes by reducing risks and enhancing recovery. Preoperative strategies, such as body fat, decreasing liver size, improving metabolic profiles, have been shown to facilitate safer procedures fewer complications. This narrative review aims provide an analysis of fundamental role preoperative nutritional management bariatric outcomes, emphasizing importance addressing specific challenges enhance safety, recovery, overall health. interventions focus on correcting comorbidities deficiencies, particularly hypovitaminosis micronutrient imbalances, through a multidisciplinary approach involving nutritionists other healthcare professionals. These not only prepare patients physiological demands but also initiate period adaptation new dietary habits, aiming improve long-term compliance mitigate postoperative weight regain dumping syndrome. Adopting changes, very low-calorie or ketogenic diets 6–12 weeks before surgery, enhances adherence restrictions success. Future research should developing comprehensive guidelines care patient globally.

Language: Английский

Citations

2

Advancing Obesity Management: the Very Low-Energy Ketogenic therapy (VLEKT) as an Evolution of the “Traditional” Ketogenic Diet DOI Creative Commons
Francesco Balestra, Maria De Luca,

G. Panzetta

et al.

Current Obesity Reports, Journal Year: 2025, Volume and Issue: 14(1)

Published: April 3, 2025

This narrative review comprehensively analyzes VLEKT as an advanced nutritional strategy for obesity management. The focus is on the beneficial effects key disease organs, such adipose tissue and liver, well modulation of intestinal permeability its fundamental role in influencing gut microbiota inflammatory pathways. impact obesity-related comorbidities, including metabolic syndrome, cardiovascular disease, endocrine disorders, dysfunction-associated steatotic liver (MASLD), neurological kidney alterations, also investigated. Moreover, to assess wider application treatment, combination ketogenic regimes with additional strategies physical activity, bariatric surgery, digital health technologies examined. Despite promising clinical results, adherence potential deficiencies require careful follow-up individualized programming monitored by specialists. Future research should elucidating molecular mechanisms underlying physiological systems, long-term safety. Nevertheless, innovative approach offering a target-oriented highly effective people fighting against overweight associated medical complications. Obesity multifactorial chronic numerous comorbidities; given increasing prevalence, personalized intervention are crucial inhibit "obesity pandemic" according "food re-educational" protocol. Among dietary interventions, diet (KD) has attracted attention effectiveness weight management benefits. A variant, very low-calorie (VLCKD), more recently defined low-energy (VLEKD), combines benefits ketosis substantial calorie restriction, improving overall health.

Language: Английский

Citations

0

Preoperative weight loss by noninvasive approach in patients with obesity scheduled for bariatric and metabolic surgery: an update narrative review of indications and results available until 2024 DOI Creative Commons

Ilenia Grandone,

Monica Nannipieri, Caterina Conte

et al.

Updates in Surgery, Journal Year: 2025, Volume and Issue: unknown

Published: April 12, 2025

Metabolic and bariatric surgery (MBS) is the most effective treatment for severe obesity its metabolic complications. Currently, MBSs are performed laparoscopically. However, high weight associated with an enlarged liver (especially left lobe section, LLLS) may complicate technical aspects of this surgery. Therefore, before MBS, moderate preoperative loss (PreopWL), reduction in LLLS desirable. Moreover, studies inconclusive regarding which best approach to apply. This narrative review aimed describe current scientific evidence on effect a noninvasive approach, such as dietary or pharmacotherapy space-occupying devices PreopWL, peri-operative complications, hospital length stay, post-operative complications patients scheduled MBS. We conducted literature search screening relevant publications from January 2010 June 2024. found that PreopWL MBS helpful both surgeons, it leads various benefits, decrease body size, lower risk intra- shorter times, reduced stays. In context, concerning approaches, several protocols have been introduced over time, among very low-calorie diets low energy ketogenic therapy widely prescribed; however, larger randomized-controlled trials (RCTs) well-defined necessary make definitive conclusions. Obesity management medications, lipase inhibitor orlistat, phentermine/topiramate, naltrexone/bupropion, glucagon-like peptide-1 receptor agonists (GLP-1RAs) liraglutide semaglutide, novel dual glucose dependent insulinotropic peptide (GIP)/GLP-1 agonist tirzepatide, has shown be promoting MBS; larger, well-designed RCTs needed establish optimal assess their true benefits Space-occupying swallowable intragastric balloon hydrogel capsules, represent promising tools but further research essential confirm role.

Language: Английский

Citations

0

The effects of protein supplementation on body composition after bariatric surgery: a systematic review and meta‐analysis of randomized controlled trials DOI
Mahsa Ranjbar, Maryam Fallah,

Kurosh Djafarian

et al.

Obesity, Journal Year: 2025, Volume and Issue: unknown

Published: May 1, 2025

Abstract Objective We aimed to explore the effect of protein supplementation on anthropometric measures and body composition in patients after metabolic bariatric surgery (MBS). Methods performed a systematic search up January 2024 including randomized controlled trials investigating effects or amino acid who underwent MBS. The overall was presented as weighted mean difference (WMD) at 95% CI. Results Ten were included this meta‐analysis. Our results indicate that there statistically greater change weight (WMD, −1.31 kg, CI: −1.93 −0.69, p < 0.001; Grading Recommendations Assessment, Development, Evaluation [GRADE] = moderate), muscle mass 1.33 0.1 2.57, 0.035; GRADE low), fat‐free 1.74 0.46 3.01, 0.01; fat −3.91 −4.10 −0.59, low) group compared control group. However, did not significantly BMI lean mass. Conclusions Based moderate‐ low‐certainty evidence, our findings suggest although may improve some metrics, it does influence More research is needed recommend

Language: Английский

Citations

0

Safety and Effectiveness of a 4-Week Diet on Low-Carb Ready-to-Eat Ketogenic Products as Preoperative Care Treatment in Patients Scheduled for Metabolic and Bariatric Surgery DOI Open Access
Biagio Santella,

Monica Mingo,

Alexander Papp

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(22), P. 3875 - 3875

Published: Nov. 13, 2024

Before metabolic and bariatric surgery (MBS), moderate weight loss liver left lateral section (LLLS) volume reduction are desirable. Low-carb ketogenic diet-induced before MBS has been shown to have beneficial effects on the in body (BW) LLLS. However, nutritional protocol of low-carb diet may be hard keep for prolonged periods due lack sweet taste. Furthermore, transitioning a can cause people crave foods that restricted diet, such as cookies, bread, pasta, bagels. Therefore, many ready-to-eat products (RLCKP) mimic carbohydrate-rich despite composition provided make it easier patients adopt lifestyle. To date, there no studies describing dietary efficient safe use pre-operative RLCKP terms LLLS with obesity scheduled MBS. aim this study was assess safety effectiveness 4-week using reducing BW Patients (

Language: Английский

Citations

3

Analysis of aborted bariatric surgeries and potential opportunities DOI

Leah M Pearl,

Oliver A. Varban, Aaron J. Bonham

et al.

Surgical Endoscopy, Journal Year: 2024, Volume and Issue: 38(9), P. 5363 - 5367

Published: July 22, 2024

Language: Английский

Citations

1

Effectiveness of ketogenic therapy in patients with obesity and diabetes: a narrative review DOI Creative Commons

Paola Pellegrini,

P Lemasson, Luca Rastrelli

et al.

Published: July 17, 2024

Over the past few decades, there has been a major increase in type 2 diabetes (T2D) prevalence, long-term medical condition which your body doesn't use insulin properly most regions of world. After adjusting for impact aging populations, prevalence adults (85–95% T2D) almost doubled between 1980 and 2020 worldwide. Increases were more pronounced low- middle-income countries men compared to women. The aim this study is evaluate performance very low-calories ketogenic diet (VLCKD) as an effective nutritional approach both TD2 obesity. A (KD) positively affects blood glucose levels, weight, glycosylated hemoglobin, neurological disorders, plasma lipid profiles. We combined ClinicalTrials.gov data from PubMed 2022. Only published papers that met requirements reporting clinical trials investigating adult sample T2D obese patients included. review shows beneficial therapeutic value VLCKD management obesity its capacity help achieve disease remission. Evidence literature underlines need redefine guidelines offer dietary low-carb option combat resistance (IR) related diseases.

Language: Английский

Citations

0

Precise nutrition in the metabolic and nutritional management of bariatric surgery: a systematic review DOI Creative Commons
Nathalia Galindo Cordeiro,

Thuany da Silva Teixeira,

Mariana Carolina Braga

et al.

International Journal of Nutrology, Journal Year: 2024, Volume and Issue: 17(S3)

Published: Aug. 2, 2024

Introduction: Obesity is a chronic relapsing disease characterized by abnormal or excessive adiposity with health risks. Any nutritional intervention in patients who are candidates for have already undergone bariatric surgery must be based on detailed assessment, including an assessment of personal values, preferences, and social determinants eating habits. Objective: It was to carry out systematic review explore present importance before, during, after surgery. Methods: The PRISMA Platform rules were followed. research carried from September October 2023 the Scopus, PubMed, Science Direct, Scielo, Google Scholar databases. quality studies GRADE instrument risk bias analyzed according Cochrane instrument. Results Conclusion: 122 articles found. A total 43 evaluated full 34 included developed study. Considering tool bias, overall resulted 22 high 26 that did not meet AMSTAR-2. Most showed homogeneity their results, X2=64.5%>50%. concluded enteral nutrition strategies could represent possible alternative other methodologies, especially when it recommended improve patient adherence diet prescribed before Weight loss induced ketogenic has beneficial effects reducing liver volume, metabolic profile, intra- postoperative complications. Knowledge type performed understanding its anatomy physiology help provide optimal care patients, Nutritional deficiencies disorders result “malabsorption” procedures, such as RYGB. essential immediately administer thiamine. Dextrose should avoided intravenous hydration until thiamine adequately replaced. For all protein intake 60-70 g/d multivitamin iron vitamin B12 supplementation recommended. Daily calcium D also encouraged. Additionally, serum micronutrient levels monitored regularly additional supplemental measures indicated.

Language: Английский

Citations

0

The Effectiveness of the Low-Glycemic and Insulinemic (LOGI) Regimen in Maintaining the Benefits of the VLCKD in Fibromyalgia Patients DOI Open Access
Giuseppe Castaldo, Carmen Marino,

Maria D’Elia

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(23), P. 4161 - 4161

Published: Nov. 30, 2024

Fibromyalgia (FM) is a chronic disorder that causes damage to the neuro-muscular system and alterations in intestinal microbiota affects psychological state of patient. In our previous study, we showed 22 women patients subjected specific very low-carbohydrate ketogenic therapy (VLCKD) an improvement clinical scores as well neurotransmission-related dysfunctions dysbiosis. Furthermore, NMR metabolomic data changes induced by VLCKD treatment were evident all metabolic pathways related fibromyalgia biomarkers.

Language: Английский

Citations

0

The Real-Life Use of a Protein-Sparing Modified Fast Diet by Nasogastric Tube (ProMoFasT) in Adults with Obesity: An Open-Label Randomized Controlled Trial DOI Open Access
Elena Formisano, Irene Schiavetti,

Raffaella Gradaschi

et al.

Nutrients, Journal Year: 2023, Volume and Issue: 15(22), P. 4822 - 4822

Published: Nov. 17, 2023

Protein-sparing modified fast (PSMF) diet is a very-low-carbohydrate ketogenic administered to patients with obesity, which preserves lean mass and suppresses appetite as well continuous enteral feeding. Thus, we aim evaluate the effect of PSMF continuously by nasogastric tube (NGT) or orally. Patients body index (BMI) > 34.9 kg/m2 were randomly assigned receive whey protein formula through NGT (ProMoFasT) Data collected at baseline after 150 days. The endpoints assessed in intention-to-treat population. We enrolled 20 ProMoFasT group 24 oral group. No differences weight, BMI waist circumference between two groups found At follow-up, FFM (%) MM results higher than (63.1% vs. 52.9%, p = 0.012 45.0% 36.1%, 0.009, respectively) FM (kg) significantly lower (36.9 kg 44.0 kg, 0.033 37.4% 44.9%, 0.012, respectively). Insulin levels follow-up (11.8 mU/L 28.0 mU/L, 0.001, more effective improving composition glucometabolic markers same

Language: Английский

Citations

0