Perspectives on Diet and Exercise Interaction for Healthy Aging: Opportunities to Reduce Malnutrition Risk and Optimize Fitness

Nutrients, Journal Year: 2025, Volume and Issue: 17(3), P. 596 - 596

Published: Feb. 6, 2025

Nutrition and exercise play a pivotal role in counteracting the effects of aging, promoting health, improving physical fitness older adults. This perspective study examines their interplay, highlighting combined potential to preserve muscle mass, cognitive function, quality life. The objective is address gaps current understanding, such as frequent neglect dietary intake interventions vice versa, which can limit effectiveness. Through synthesis existing literature, we identify key findings, emphasizing importance adequate nutritional intake—particularly protein, essential amino acids, micronutrients—in supporting benefits preventing sarcopenia malnutrition. Additionally, supplementation strategies, omega-3 fatty creatine, are explored alongside emerging gut microbiota mediating nutrition exercise. Despite these advances, challenges remain, including determining optimal dosages timing addressing individual variability responses. Personalized approaches tailored sex differences, diversity, baseline health conditions critical for maximizing intervention outcomes. Our conclusions underscore necessity integrated strategies that align support healthy active aging. By gaps, future research provide actionable insights optimize life populations.

Language: Английский

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Potential therapeutic solution for Clostridioides difficile infection: current scenario and future prospects

Medicine in Microecology, Journal Year: 2025, Volume and Issue: unknown, P. 100121 - 100121

Published: Feb. 1, 2025

Language: Английский

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Plant-Based Diets and Their Role in Preventive Medicine: A Systematic Review of Evidence-Based Insights for Reducing Disease Risk

Cureus, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 6, 2025

Plant-based diets have gained increasing attention for their potential role in preventive medicine, particularly reducing the risk of chronic diseases such as type 2 diabetes, cardiovascular disease, obesity, and metabolic syndrome. This systematic review synthesizes evidence from 32 longitudinal studies to evaluate impact plant-based on disease prevention health outcomes. The identifies consistent patterns, including improved health, weight management, reduction, positive effects gut microbiome composition inflammation. However, inconsistencies arise due variability diet definitions, mixed findings specific outcomes, heterogeneity study populations. Critical gaps literature include lack long-term studies, limited mechanistic insights, underrepresentation diverse populations, a need more rigorous intervention personalized nutrition approaches. Identified research highlight deeper exploration pathways, greater inclusivity These insights underscore significance cornerstone medicine while emphasizing necessity targeted interventions approaches maximize benefits. contribute growing body supporting integration dietary strategies into public policies clinical practices.

Language: Английский

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Implications of a Plant-Based Diet in the Surgical and Critically Ill Patient

Current Surgery Reports, Journal Year: 2025, Volume and Issue: 13(1)

Published: Feb. 14, 2025

Language: Английский

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Umbrella review of systematic reviews and meta-analyses on consumption of different food groups and risk of all-cause mortality

Advances in Nutrition, Journal Year: 2025, Volume and Issue: unknown, P. 100393 - 100393

Published: Feb. 1, 2025

Consumption of different food groups is linked to a range health outcomes. It essential integrate the most reliable evidence regarding intake and risk mortality optimize dietary guidance. Our aim systematically comprehensively assess associations between consumption various all-cause mortality. The under consideration include edible grains (refined whole grains), fruits, vegetables, nuts, legumes, fish products, eggs, dairy products/milk, meat products (including processed meat, unprocessed red white meat), sugar-sweetened beverages, added sugars. We present these with high versus low per serving comparisons. reviewed search in Medline, Embase, Web Science, Epistemonikos (PROSPERO: CRD42024498035), identifying 41 meta-analyses involving over million participants, many which showed significant heterogeneity. Of studies, 18 were rated quality, 8 moderate 5 10 critically quality according AMSTAR-2 assessments. findings revealed that higher grains, vegetables was associated lower rates, both comparisons analyses. Similarly, we observed favorable outcomes for legumes Conversely, intakes meats, as well Dairy refined did not show clear mortality, while there tendency sugars eggs.

Language: Английский

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Insights from omics research on plant-based diets and cardiometabolic health

Trends in Endocrinology and Metabolism, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

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A Plant-Dominant Low-Protein Diet in Chronic Kidney Disease Management: A Narrative Review with Considerations for Cyprus

Nutrients, Journal Year: 2025, Volume and Issue: 17(6), P. 970 - 970

Published: March 10, 2025

Chronic kidney disease (CKD) is a major global health challenge, significantly contributing to morbidity and mortality due its strong association with cardiovascular complications, metabolic imbalances, reduced quality of life. Among the various interventions for CKD management, nutrition therapy plays critical role in slowing progression improving patient outcomes. The Plant-Dominant Low-Protein Diet (PLADO) has emerged as promising dietary strategy that prioritizes plant-based protein sources while restricting overall intake, offering potential renal, cardiovascular, benefits. This review evaluates current evidence on efficacy PLADO analyzing impact renal function, health, systemic inflammation. Key findings suggest can delay progression, reduce dialysis dependence, mitigate risks through lower acid load, increased fiber anti-inflammatory properties. Additionally, been shown support gut microbiota diversity uremic toxin production, advantages beyond health. While appears nutritionally adequate, concerns remain regarding sufficiency, potassium long-term adherence. Its successful implementation requires tailored meal planning, education, regular clinical monitoring optimize outcomes risks. highlights importance integrating into management holistic, patient-centered approach, particularly regions like Cyprus, where no studies have evaluated applicability. By synthesizing existing research, this provides insights clinicians, dietitians, researchers further explore outcomes, adherence strategies, feasibility across diverse healthcare settings. Future should focus large-scale randomized controlled trials (RCTs) establish PLADO’s guidelines practice.

Language: Английский

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Diabetes, obesity, and cardiovascular disease—what is the impact of lifestyle modification?

Herz, Journal Year: 2025, Volume and Issue: unknown

Published: March 14, 2025

Language: Английский

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Gut microbiome diversity and nutrition intake in post‐stroke patients

Geriatrics and gerontology international/Geriatrics & gerontology international, Journal Year: 2025, Volume and Issue: unknown

Published: March 17, 2025

Aim This study aimed to investigate the association between energy intake and gut microbiome diversity in patients following stroke. Methods A cross‐sectional was conducted with 156 stroke aged ≥65 years admitted a rehabilitation hospital (mean age, 78 ± 7 years; 69 women). Energy calculated from average food consumption during first week after admission. Gut assessed using three indices derived 16S rRNA sequencing of stool samples: Shannon index, operational taxonomic unit (OTU) richness Faith's phylogenetic (PD). Sex‐stratified multiple linear regression analysis evaluated diversity, adjusting for confounders such as body weight, inflammation markers, nutritional status, medication. Results The included median 1600 (interquartile range [IQR], 1400–1800] kcal/day all participants. were 6.3 (IQR, 5.9–6.5); OTU richness, 217.3 181.9–258.1); PD, 22.4 19.3–27.2). In women, significantly positively associated index (β = 0.233, P 0.026), 0.228, 0.036), PD 0.212, 0.038). men, 0.230, 0.027), 0.211, 0.040), 0.198, 0.043). Conclusions Adequate may play an important role preserving patients. Further longitudinal studies are needed confirm these associations, clarify causality, explore underlying mechanisms. Geriatr Gerontol Int 2025; ••: ••–•• .

Language: Английский

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Diet, microbiome, and probiotics establish a crucial link in vaccine efficacy

Critical Reviews in Microbiology, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 26

Published: March 20, 2025

Vaccination plays a critical role in public health by reducing the incidence and prevalence of infectious diseases. The efficacy vaccine has numerous determinants, which include age, sex, genetics, environment, geographic location, nutritional status, maternal antibodies, prior exposure to pathogens. However, little is known about gut microbiome how it can be targeted through dietary interventions improve immunological responses. Unveiling this link imperative, particularly post-pandemic world, considering impaired COVID-19 response observed dysbiotic individuals. Therefore, article aims comprehensively review diet probiotics modulate composition, linked efficacy. Dietary fiber polyphenolic compounds derived from plant-based foods microbial diversity promoting growth short-chain fatty acids-producing microbes. On other hand, animal-based have mixed effects – whey protein fish oil promote eubiosis In contrast, lard red meat adverse effects. Studies further indicate that probiotic supplements exert varied effects, mostly strain dosage-specific. Interlinking diet, microbiome, probiotics, vaccines will reveal opportunities for newer research on diet-induced microbiome-manipulated precision vaccination strategies against

Language: Английский

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