Exploring the underlying mechanisms of obesity and diabetes and the potential of Traditional Chinese Medicine: an overview of the literature

Frontiers in Endocrinology, Journal Year: 2023, Volume and Issue: 14

Published: Aug. 1, 2023

Obesity and diabetes are closely related metabolic disorders that have become major public health concerns worldwide. Over the past few decades, numerous studies explored underlying mechanisms of these identified various risk factors, including genetics, lifestyle, dietary habits. Traditional Chinese Medicine (TCM) has been increasingly recognized for its potential to manage obesity diabetes. Weight loss is difficult sustain, several diabetic therapies, such as sulfonylureas, thiazolidinediones, insulin, might make it harder lose weight. While lifestyle changes should be primary approach people interested in lowering weight, drugs also worth investigating. Since some newer glucose-lowering medications cause weight loss, glucagon-like peptide-1 receptor agonists (GLP-1 RAs) sodium-glucose cotransporter 2 inhibitors (SGLT2i), additionally utilized or under consideration use anti-obesity drugs, frontier between medication appears shifting. This review provides an overview literature on prospect TCM their management. We discuss interventions, acupuncture, herbal medicine, therapy, effects health. highlight regulating gut microbiota, reducing inflammation, improving insulin sensitivity. The findings suggest may provide a promising preventing managing However, further well-designed needed confirm efficacy safety interventions elucidate action.

Language: Английский

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Moringa oleifera Lam. as a potential plant for alleviation of the metabolic syndrome—A narrative review based on in vivo and clinical studies

Phytotherapy Research, Journal Year: 2023, Volume and Issue: 38(2), P. 755 - 775

Published: Nov. 28, 2023

Abstract The metabolic syndrome (MetS) refers to the co‐occurrence of risk factors, including hyperglycaemia, increased body weight, hypertension and dyslipidemia, which eventually lead diabetes cardiovascular disease, a common health problem worldwide. Recently, there has been an increasing interest in use plant‐based products for management MetS, because their less detrimental more beneficial effects. Moringa oleifera (Moringaceae), commonly known as drumstick, is cultivated worldwide its nutritional medicinal properties. This review focuses on vivo human studies concerning potential M. alleviation MetS comorbidities. search relevant articles was carried out PubMed Google Scholar databases. Randomised controlled clinical trials from database were included this review. results suggested that administration , vivo, shows clear signs improvement indices. Despite fewer studies, existing data documented convincing uphold against MetS. Therefore, future research discussing probable mechanism action much needed could further assure usage treatment regimen

Language: Английский

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Dilemmas in Elderly Diabetes and Clinical Practice Involving Traditional Chinese Medicine

Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(7), P. 953 - 953

Published: July 16, 2024

Diabetes is a widespread chronic disease that occurs mainly in the elderly population. Due to difference pathophysiology between and young patients, current clinical practice treat patients with anti-diabetes medications still faces some challenges dilemmas, such as urgent need for early diagnosis prevention, an imbalance restricted dietary intake risk of undernutrition. Traditional Chinese medicine (TCM) offers various treatment regimens are actively utilized field diabetes management. Through multiple targets pathways, TCM formulas, medicinal herbs, active natural products enhance efficacy prevention control measures, simplify complex medication management, improve common symptoms diabetic complications people. Historically, have played key role material composition analysis mechanism interpretation enable drug discovery. However, there been few conclusions on this topic. This review summarizes development management people, existing evidence-based practices, prospects future development.

Language: Английский

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Fabrication and characterization of potato short amylose, zein, and pectin ternary composite particles stabilized pickering emulsions and their application on nuciferine delivery

Food Research International, Journal Year: 2024, Volume and Issue: 197, P. 115187 - 115187

Published: Oct. 5, 2024

Language: Английский

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