Microorganisms,
Journal Year:
2024,
Volume and Issue:
12(12), P. 2542 - 2542
Published: Dec. 10, 2024
Dysfunction
in
the
prefrontal
cortex
can
lead
to
cognitive
inflexibility
due
multifactorial
causes
as
included
cardiometabolic
disorders,
stress,
inadequate
diets,
well
an
imbalance
of
gut-brain
axis
microbiota.
However,
these
risk
factors
have
not
been
evaluated
jointly.
The
purpose
this
study
was
evaluate
effect
physical
stress
(MS:
Male
Stress
and
FS:
Female
Stress)
high-fat
diet
(MD:
Diet
FD:
Diet)
supplementation
on
gut
microbiota
flexibility.
performed
47
mice,
30
male
(M)
17
female
(F)
BALBc,
exposed
chronic
(S)
(D).
Cognitive
flexibility
using
Attentional
Set-Shifting
Test
(ASST)
composition
terms
relative
abundance
(%)
alpha-beta
diversity.
Results
showed
that
S
D
reduced
mice
(
Chronic
a
modify
predictive
function
Applied Sciences,
Journal Year:
2024,
Volume and Issue:
14(9), P. 3882 - 3882
Published: May 1, 2024
Weight
loss
solutions
are
on
the
rise,
and
there
is
growing
interest
in
natural
alternatives
to
pharmaceuticals
market,
which
not
devoid
of
relevant
side
effects.
To
this
end,
objective
current
study
was
assess
effects
a
botanical-based
blend
comprised
lemon
verbena
hibiscus
extracts
weight
management,
body
fat,
appetite,
lipid,
glucose
profiles
an
overweight
population
for
90
days.
The
volunteers
presented
significant
absence
diet
(approximately
3
kg,
−3.4%
total
weight),
coincided
with
decreased
fat
(−1.7%,
equivalent
almost
6%
decrease
compared
initial
value).
Body
assessed
by
anthropometry,
electrical
bioimpedance
DEXA
scans.
Cholesterol
levels
were
also
significantly
7%
decrease).
Satiety
assessment
revealed
that
product
contributed
increased
feeling
fullness
satisfaction
after
meal
placebo
group,
could
contribute
observed.
Blood
blood
pressure
remained
unchanged,
expected
as
normoglycemic
their
healthy
range.
In
conclusion,
daily
supplementation
contributes
individuals
diet,
while
affecting
other
parameters
This
be
candidate
alternative
or
add-on
products
part
lifestyle.
bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: July 16, 2024
Abstract
The
prevalence
of
neurodegenerative
diseases,
such
as
Alzheimer’s
disease
and
Parkinson’s
disease,
is
steadily
increasing,
posing
significant
challenges
to
global
healthcare
systems.
Emerging
evidence
suggests
that
dietary
habits,
particularly
consumption
high-fat
diets
specify
which
fats,
may
play
a
pivotal
role
in
the
development
progression
disorders.
Moreover,
several
studies
have
shed
light
on
intricate
communication
between
gut
brain,
known
gut-brain
axis
its
involvement
processes.
This
study
aims
assess
effects
intake
various
aspects
neuronal
function
during
aging
following
gender
separation
help
understand
potential
contributions
diet
function.
To
investigate
diet,
Drosophila
melanogaster
was
used
exposed
standard
normal
food
(NF)
(HF).
Adults
were
grouped
at
10
45
days
age
male
female
flies
reared
under
same
conditions.
Multiple
assays
conducted,
showing
differential
gender-
HF
diet-induced
oxidative
stress
levels
determined
by
malondialdehyde
(MDA)
measurements,
enhanced
caspase-3
expression
reduced
climbing
activity.
Adult
lifespan
both
conditions
unchanged
but
odour-associated
learning
ability
larvae
diet.
first
characterise
phenotypes
an
age-
gender-specific
manner
model.
Our
findings
suggest
induces
forms
dysfunction
with
sex-specific
outcomes,
characterised
cell
death
impacts
behavioural
functions.
Российский физиологический журнал им И М Сеченова,
Journal Year:
2024,
Volume and Issue:
110(2), P. 254 - 267
Published: Aug. 2, 2024
Nowadays
phospholipids
are
widely
used
as
hepatoprotective,
neuroprotective
and
anti-stress
drugs,
well
the
dietary
supplements.
Besides,
lecithin
consisting
up
to
70%
of
mixture:
phosphatidylcholine,
phosphatidylethanolamine,
phosphatidylinositol
phosphatidic
acid,
is
often
component
food
production
an
emulsifier.
Dose
these
biologically
active
substances
in
modern
human
diet
could
be
quite
high.
Previously
we
have
shown
that
chronic
intestinal
inflammation
Muc2-knockout
mice
induces
behavioral
changes
along
with
significant
increase
content
epithelial
cells,
particularly,
phosphatidylserine
acid.
Here
investigate
effects
long-term
administration
a
mixture
phospholipids,
soy
on
patterns
laboratory
mice.
Animals
taken
phospholipid
shows
no
normally
observed
preference
towards
females
two
intruders
test
(with
female
male).
In
social
odor
test,
they
also
did
not
distinguish
male
odors,
while
non-social
odors
discrimination
preserved.
addition,
identified
decrease
anxiety,
obsessive
traits,
schizophrenia-like
behavior
traits
animals.
Soy
supplementation
had
similar
compulsive
increased
aggression
males.
Thus,
perinatal
either
(phosphatidylcholine,
acid)
or
can
influence
various
aspects
Microorganisms,
Journal Year:
2024,
Volume and Issue:
12(12), P. 2542 - 2542
Published: Dec. 10, 2024
Dysfunction
in
the
prefrontal
cortex
can
lead
to
cognitive
inflexibility
due
multifactorial
causes
as
included
cardiometabolic
disorders,
stress,
inadequate
diets,
well
an
imbalance
of
gut-brain
axis
microbiota.
However,
these
risk
factors
have
not
been
evaluated
jointly.
The
purpose
this
study
was
evaluate
effect
physical
stress
(MS:
Male
Stress
and
FS:
Female
Stress)
high-fat
diet
(MD:
Diet
FD:
Diet)
supplementation
on
gut
microbiota
flexibility.
performed
47
mice,
30
male
(M)
17
female
(F)
BALBc,
exposed
chronic
(S)
(D).
Cognitive
flexibility
using
Attentional
Set-Shifting
Test
(ASST)
composition
terms
relative
abundance
(%)
alpha-beta
diversity.
Results
showed
that
S
D
reduced
mice
(
Chronic
a
modify
predictive
function
