DIETARY STRATEGIES FOR MANAGING OBESITY AND POLYCYSTIC OVARY SYNDROME (PCOS) DOI Creative Commons

José Ribamar Sousa Da Cruz

Revista Sistemática, Journal Year: 2024, Volume and Issue: 14(8), P. 576 - 583

Published: Dec. 13, 2024

Obesity and polycystic ovary syndrome (PCOS) are often interrelated conditions, both exacerbated by insulin resistance hormonal imbalances. Managing these conditions requires a multidisciplinary approach, with dietary interventions playing central role. Two common strategies explored for weight management in PCOS hypocaloric ketogenic diets, each distinct mechanisms benefits. Hypocaloric diets focus on reducing daily caloric intake, promoting gradual sustainable loss, which can improve sensitivity reduce androgen levels, alleviating symptoms such as menstrual irregularities acne. However, loss may be slower, do not directly address resistance. On the other hand, involve drastically carbohydrate intake increasing fat consumption, inducing ketosis, leading to rapid loss. This approach has shown significant benefits women severe obesity resistance, improving metabolic markers like glucose cholesterol levels enhancing balance. restrictive nature of diet make long-term adherence difficult, side effects “keto flu” hinder its success. Research studies have demonstrated that effective managing PCOS, offering faster results providing Ultimately, choice between should personalized, taking into account patient’s profile, preferences, health goals. Continuous professional monitoring is essential ensure nutritional adequacy prevent complications. A holistic, individualized combining diet, exercise, medical supervision, effectively PCOS.

Language: Английский

High Fat Diet and Polycystic Ovary Syndrome (PCOS) in Adolescence: An Overview of Nutritional Strategies DOI Open Access
Valeria Calcaterra,

Vittoria Carlotta Magenes,

Giulia Massini

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(7), P. 938 - 938

Published: March 24, 2024

Polycystic ovary syndrome (PCOS) is a multifaceted and heterogeneous disorder, linked with notable reproductive, metabolic, psychological outcomes. During adolescence, key components of PCOS treatment involve weight loss achieved through lifestyle dietary interventions, subsequently pursued by pharmacological or surgical therapies. Nutritional interventions represent the first-line therapeutic approach in adolescents affected PCOS, but different kinds protocols exist, so it necessary to clarify effectiveness benefits most well-known nutritional approaches. We provided comprehensive review current literature concerning definition, pathophysiology, options, highlighting strategies, particularly those related high-fat diets. The proposed literature, such as ketogenic diet (KD), appear provide patients terms control metabolic parameters. Among types KD studies, very low-calorie diets (VLCKD), can be considered an effective intervention for short-term PCOS. It rapidly leads alongside improvements body composition profile. Even though extremely advantageous, long-term adherence limiting factor. Indeed, this regimen could become unsustainable due important restrictions required ketosis development. Thus, combination more nutrient-rich regimens, Mediterranean diet, amplify positive effects individuals

Language: Английский

Citations

8
The Role of Diet, Glycaemic Index and Glucose Control in Polycystic Ovary Syndrome (PCOS) Management and Mechanisms of Progression DOI Creative Commons
Claire Johnson, Gökçen Garipoğlu, Yvonne Jeanes

et al.

Current Nutrition Reports, Journal Year: 2025, Volume and Issue: 14(1)

Published: Jan. 3, 2025

Abstract Purpose of Review Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder with several causal pathways including impaired glucose tolerance, insulin resistance (IR), compensatory hyperinsulinemia and excess androgens (hyperandrogenism). This heterogeneous condition causes range reproductive, metabolic psychological implications, the severity which can differ between individuals depending on factors such as age, diet, ethnicity, genetics, medication, contraceptive use, adiposity, Body Mass Index (BMI). Recent Findings Dietary interventions that focus low glycaemic index control are an efficient first-line dietary solution for management tolerance IR, subsequently improves weight management, quality life PCOS-related symptoms in this condition. Summary review aims to explore relevance nutrition more specifically, association load PCOS, well assess potential benefits manipulating those indexes approach syndrome.

Language: Английский

Citations

0
Macronutrients and Disease: Polycystic Ovary Syndrome DOI
Fahimeh Ramezani Tehrani, Marzieh Saei Ghare Naz

Published: Jan. 1, 2025

Language: Английский

Citations

0
Maturation Performance of Snakehead Fish (Channa Striata) with The Percentage of Feed for Rice Field Snails (Pila Ampullacea) with The Addition of Vitamin E DOI Open Access

Md Abu Raihan,

Untung Bijaksana,

Agussyarif Hanafie

et al.

IOP Conference Series Earth and Environmental Science, Journal Year: 2025, Volume and Issue: 1468(1), P. 012014 - 012014

Published: March 1, 2025

Abstract Snakehead fish (Channa striata) is a native that lives in Indonesia’s public waters which increasingly economically valuable. Cultivating this challenge the gonad maturation process takes long time to spawn. Gonadal maturity can be achieved by hormonal manipulation, environment, and provision of quality natural feed. One feeds used rice field snails (Pila ampullacea) are rich protein, as well addition vitamin E. This study analyzed effects feed E on reproductive performance snakehead fish, giving percentage 3%, 5% 7% satiation. Using Complete Random Design with 4 treatments 3 replicates. The results showed feeding improved an average GMR III-IV, gonadosomatic index 1.34 – 2.60%, hepatosomatic 0.84 0.95%.

Language: Английский

Citations

0
Dyslipidaemia in women with polycystic ovary syndrome referred to a teaching hospital in Cape Town, South Africa DOI Creative Commons
A. David Marais,

Anne Hoffman,

Diane Mary Blackhurst

et al.

Journal of Neuroendocrinology, Journal Year: 2024, Volume and Issue: 36(10)

Published: June 10, 2024

Abstract The polycystic ovary syndrome (PCOS) imparts health risks including dyslipidaemia, diabetes and cardiovascular disease that are amenable to lifestyle adjustment and/or medication. We describe dyslipidaemia in women referred a gynaecological endocrine clinic. Clinical data lipoprotein investigations comprising fasting triglyceride (TG), total cholesterol (TC), high density (HDLC) calculated low (LDLC) were studied along with electrophoresis patterns of apolipoprotein B‐containing lipoproteins. 1721 participants comprised black, mixed ancestry, white Indian individuals (9.8%, 83.2%, 5.8% 1.2%, respectively). mean ± standard deviation the age, body mass index (BMI) waist/hip ratio 26.0 5.9 years, 32.3 8.3 kg/m 2 0.88 0.11, respectively. Overweight status (BMI 26–30 ) obesity >30 involved 272 (15.8%) 1010 (58.7%) individuals, Morbid >40 was present 309 (17.9%) individuals. TG, TC, HDLC LDLC concentrations 1.22 0.86, 4.77 1.02, 1.3 0.36, 2.94 0.94 mmol/L, LDL hypercholesterolaemia occurred 753 (43.7%) exceeded 5 mmol/L 39 (2.3%) women. Low (<0.9 mmol/L) affected 122 (7%), hypertriglyceridaemia (>1.7 265 (15.4%) 2.5 91 (5.3%) Mixed hyperlipidaemia (TG >1.7, TC >5.0 176 (10.2%). Electrophoresis revealed small particles 79 (4.6%) dysbetalipoproteinaemia 13 (0.76%) cohort. Small associated obesity, blood pressure, TG glucose concentration higher androgenic state. Many PCOS had unfavourable results: mostly moderate changes LDLC. is not rare, may aid risk assessment best determined directly. Incidental monogenic disorders metabolism included dysbetalipoproteinaemia, familial severe hypertriglyceridaemia. Dyslipidaemia requires more careful diagnosis, individualised management research.

Language: Английский

Citations

1
Efficacy of low carbohydrate ketogenic diet in weight management: A narrative review DOI
Sabrina Zaman,

Tamsel Ahammed

Obesity Medicine, Journal Year: 2024, Volume and Issue: 49, P. 100550 - 100550

Published: July 16, 2024

Language: Английский

Citations

1
Nutritional Studies Evaluating Ketogenic Diets as a Treatment for Obesity and Obesity-Associated Morbidities: Underlying Mechanisms and Potential for Clinical Implementation DOI Creative Commons
Luciano Pirola, Karolina Maria Górecka, Carol Góis Leandro

et al.

Endocrines, Journal Year: 2024, Volume and Issue: 5(4), P. 585 - 599

Published: Dec. 3, 2024

Background: The ketogenic diet (KD), characterized by high-fat content, virtually no carbohydrates, and adequate protein intake, induces a metabolic state resembling fasting, as the absence of carbohydrates forces body to rely on energetic supply from hepatically produced ketone bodies using free fatty acids substrate. While KD is clinically used in pharmacologically refractory epilepsy specific genetic conditions such GLUT1 deficiency, recent research suggests that, due its “fasting mimicking” properties, may also beneficially affect obesity obesity-associated diseases. Results: Here, we present narrative review discussing completed ongoing nutritional studies human volunteers specifically addressing potential an anti-obesity approach and, larger perspective, intervention ameliorate type 1 2 diabetes polycystic ovary syndrome (PCOS). Published well clinical trials will be discussed. Efficacy safety considerations discussed, physiological mechanisms mediating effects humans context (i) energy balance model (EBM) (ii) carbohydrate–insulin (CIM) weight control. Conclusion: Ketogenic diets beneficial attenuate improve obesity-related disease, here, try, based current evidence, define boundaries KD’s usefulness.

Language: Английский

Citations

1
Ketogenic diet for ovarian disorders - promising nutritional approach in polycystic ovarian syndrome and ovarian cancer DOI Creative Commons
Magda Wojtuś, Sebastian Tomaszuk, Karolina Wąsik

et al.

Journal of Education Health and Sport, Journal Year: 2024, Volume and Issue: 65, P. 49846 - 49846

Published: April 12, 2024

Introduction and purpose: Polycystic ovary syndrome (PCOS) is the most common endocrine disease in female reproductive age. As treatment guidelines include lifestyle changes, various diet types are being evaluated terms of efficacy among them ketogenic (KD) which was also assessed its influence on another ovarian related - cancer. The aim this paper an analysis available scientific data respect role KD as a part therapy disorders. search conducted using PubMed Google Scholarship databases. Brief description state knowledge: Ketogenic demonstrates favorable effects hormonal profile PCOS-affected women. It noticed that administration results reduction BMI improvement glycemic parameters. Most research by linking with caloric restriction. In matter cancer unclear; some states quality life participants, but there alarming possible enhancing tumor growth. Conclusions: merits further factor PCOS foregoing pointing to efficacy. Nevertheless, still more needed determine studies were within short period time relatively small groups. There other limitations such lack comparison dietary patterns deficit makes it difficult deduce main profitable factor. When comes current unclear unambiguous negative effects.

Language: Английский

Citations

0
Development Of "SEHATI" Application To Improve Adolescent's Understanding Of Reproductive Health DOI

Intan Kumalasari,

Herawati Jaya

Journal of Applied Nursing and Health, Journal Year: 2024, Volume and Issue: 6(1), P. 91 - 101

Published: June 27, 2024

Background: Adolescent Reproductive Health (KRR) is a government program in Indonesia that has been implemented since 2000. The aim to ensure the young generation healthy and prosperous. Teenagers are still looking for answers reproductive health problems themselves, consulting friends, social media other online sources because they do not fully understand material offered this program. Adolescents may be more likely participate risky behavior, such as engaging sexual intercourse at younger age, due ease of obtaining information. Methods: "SEHATI" app, developed result research, will teach teenagers about health. By using ADDIE methodology (analysis, design, development, implementation evaluation), research adheres Research Development approach. Results: Media experts gave product validation score 75%, 100%, educational practitioners 99.5%, all which indicate very suitable use. Scores 77.3% 88% were achieved small-group trials large-group trials, respectively. This shows how well works. As many 89% students positive throughout evaluation stage. Conclusion: With an 80% increase student understanding, app great potential future improvements terms content, realism, language, presentation, graphics learning motivation with hope becoming resource learn

Language: Английский

Citations

0
Retinol intake and PCOS management: a plasma metabolite and protein analysis via Mendelian randomization and NHANES 2011–2016 DOI Creative Commons
Peng Chen,

Sha Ni,

Qifang Liu

et al.

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: Oct. 23, 2024

Background Polycystic Ovary Syndrome (PCOS) represents a complex endocrine disorder characterized by significant interplay with metabolic dysfunction and obesity. This research endeavors to elucidate the causal dynamics among plasma metabolites, proteins, PCOS, alongside Body Mass Index (BMI), pinpoint prospective therapeutic interventions. Methods investigation employed Mendelian randomization (MR) analyses combined data derived from National Health Nutrition Examination Survey (NHANES) explore relationships between 1,400 metabolites factoring in BMI adjustments. Additionally, study examined influence of proteins performed retrospective cross-sectional analysis focusing on retinol consumption testosterone levels. Results MR showed metabolite Glycosyl-N-(2-hydroxynervonoyl)-sphingosine (GNS) protein Keratin 19 (KRT19) were identified as markers context PCOS A Phenome-Wide Association Study (PheWAS) underscored linkage KRT19 BMI, while gene-drug interaction findings demonstrated connection retinol. Analysis for NHANES disclosed negative correlation intake levels, particularly within normal weight obese cohorts, suggesting feasibility dietary interventions management. Conclusion The sheds light intricate interactions considering variations, highlights promising target. outcomes support integration into strategies regulate levels potentially alleviate symptoms, underscoring necessity personalized nutritional approaches effective management PCOS.

Language: Английский

Citations

0