Sleep Medicine Reviews,
Journal Year:
2024,
Volume and Issue:
77, P. 101969 - 101969
Published: June 18, 2024
Eating
disorders
(ED)
are
psychological
characterized
by
dangerous
eating
behaviours,
including
protracted
fasting
and
binge
eating.
Mental
comorbidities
(e.g.,
anxiety
depression),
as
well
sleep
difficulties,
common
might
interfere
with
treatment
response.
This
work
investigated
quality,
circadian
preferences,
in
ED
patients
compared
to
healthy
controls
(HC)
the
impact
of
on
patients'
sleep.
A
literature
search
Pubmed,
Web
Science,
Medline,
PsychInfo
included
27
studies.
Random
effect
analyses
were
performed
(sample
=
711;
sample
653)
subgroup
calculated
based
subgroups:
Anorexia
Nervosa,
Bulimia
Binge
Disorder.
Whole
showed
poorer
physiological
subjective
quality
patients.
Subgroup
that
was
present
only
anorexia
nervosa.
Two
studies
reporting
preferences
higher
evening
preference
no
differences
apnea
prevalence
between
controls,
respectively.
Some
suggested
specialized
disorder
treatments
Cognitive
Behavioural
Therapy
for
ED)
can
improve
Although
these
findings
highlight
mechanisms
underlying
alterations
remain
be
identified.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(5), P. 609 - 609
Published: Feb. 23, 2024
Low
energy
availability
(LEA)
has
been
associated
with
several
physiological
consequences,
but
its
impact
on
sleep
not
sufficiently
investigated,
especially
in
the
context
of
young
athletes.
This
study
examined
potential
association
between
(EA)
status
and
objective
quality
42
male
rugby
players
(mean
age:
16.2
±
0.8
years)
during
a
7-day
follow-up
fixed
schedules
midst
an
intensive
training
phase.
Participants’
intake
was
weighed
recorded.
Exercise
expenditure
estimated
using
accelerometry.
Portable
polysomnography
devices
captured
last
night
follow-up.
Mean
EA
29.3
9.14
kcal·kg
FFM−1·day−1,
47.6%
athletes
presenting
LEA,
35.7%
Reduced
Energy
Availability
(REA),
16.7%
Optimal
(OEA).
Lower
efficiency
(SE)
N3
stage
proportion,
along
higher
wake
after
onset
(WASO),
were
found
participants
LEA
compared
to
those
OEA
(p
=
0.04,
p
0.03
0.005,
respectively,
large
effect
sizes).
Segmented
regression
models
EA-sleep
outcomes
(SE,
latency
[SOL]),
WASO
N3)
relationships
displayed
two
separate
linear
regions
produced
best
fit
breakpoint
21–33
FFM−1·day−1.
Below
these
thresholds,
declines
considerably.
It
is
imperative
for
athletic
administrators,
nutritionists,
coaches
conscientiously
consider
athletes’
sleep,
periods
heavy
training.
Cells,
Journal Year:
2024,
Volume and Issue:
13(15), P. 1246 - 1246
Published: July 24, 2024
The
triadic
interplay
between
sleep,
immunity,
and
cancer
represents
a
growing
area
of
biomedical
research
with
significant
clinical
implications.
This
review
synthesizes
the
current
knowledge
on
how
sleep
influences
immune
function,
system’s
role
in
dynamics,
direct
connections
patterns
risk.
After
comprehensive
overview
interrelationships
among
these
three
domains,
mechanisms
function
are
described,
detailing
regulates
system,
effects
duration
quality
responses,
underlying
molecular
cellular
mechanisms.
Also,
complex
relationship
immunity
is
explored,
highlighting
prevention
progression,
surveillance,
tumor
microenvironment,
implications
immunodeficiency
modulation
then
presenting
epidemiological
evidence
linking
to
risk,
biological
that
influence
development,
disorders
prognosis.
mediating
highlighted,
proposing
hypothesized
pathways,
summarizing
from
experimental
studies,
evaluating
impact
interventions
outcomes.
concludes
by
discussing
future
directions,
emphasizing
potential
for
sleep-based
treatment,
integration
management
oncology
immunotherapy,
outlining
agenda.
agenda
includes
understanding
sleep–immunity–cancer
interplay,
conducting
studies
assessing
treatment
protocols,
exploring
microenvironment
interactions,
considering
policy
public
health
Through
detailed
examination
interconnected
this
underscores
critical
importance
modulating
outcomes,
advocating
interdisciplinary
strategies
harness
improved
International Clinical Psychopharmacology,
Journal Year:
2023,
Volume and Issue:
39(3), P. 127 - 138
Published: Dec. 27, 2023
Nearly
one-third
of
all
stroke
patients
develop
depression
at
any
time
after
a
stroke,
and
its
presence
is
associated
with
unfavorable
outcomes.
This
narrative
review
aims
to
provide
synopsis
possible
pharmacological
non-pharmacological
treatment
modalities
for
post-stroke
(PSD).
Several
studies
have
demonstrated
the
efficacy
safety
selective
serotonin
reuptake
inhibitors
in
treating
symptoms
this
clinical
condition.
The
PSD
has
been
recently
enhanced
by
innovative
approaches,
such
as
cognitive-behavioral
therapy,
virtual
reality,
telehealth,
repetitive
transcranial
magnetic
stimulation,
non-conventional
therapies,
which
might
improve
survivors.
Future
high-quality
randomized
controlled
trials
are
necessary
confirm
hypothesis.
(1)
Background:
Gamma-aminobutyric
acid
(GABA)
is
one
of
the
inhibitory
neurotransmitters
with
beneficial
effects
including
sedative
property.
However,
despite
various
clinical
trials,
scientific
evidence
regarding
impact
orally
ingested
GABA,
whether
natural
or
synthesized
through
biological
pathways,
on
sleep
not
clear.;
(2)
Methods:
The
present
study
work
evaluated
GABA-A
biding
affinity
GABALAGEN(GBL),
a
low-molecular-weight
collagen
infused
receptor
binding
assays.
GBL
were
investigated
electroencephalography
(EEG)
analysis
in
electro
foot
shock
(EFS)
stress-induced
animal
model
and
then
we
examined
expression
orexin,
GABAA
brain
region
using
immunohistochemistry.;
(3)
Results:
We
found
that
assay,
displayed
high
to
(IC50
value,
31.5µg/mL)).
Also,
after
treatment
GBL,
percent
total
time
REM
NREM
significantly
dose-dependently
increased
compared
Con
group.
Consistent
behavioral
results,
GBL-treated
groups
showed
immune-positive
cells
VLPO
markedly
orexin
immune-reactive
LH
decreased
group.;
(4)
Conclusions:
In
conclusion,
efficacy
potential
be
used
as
an
anti-stress
therapy
treat
deprivation
antagonism
GABA
receptors
consequent
inhibition
activity.
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(18), P. 9791 - 9791
Published: Sept. 10, 2024
Grounding,
a
therapeutic
technique
involving
direct
contact
with
the
earth,
has
been
proposed
by
various
studies
to
potentially
have
beneficial
effects
on
pressure,
sleep
quality,
stress,
inflammation,
and
mood.
However,
scientific
evidence
supporting
its
sedative
remains
incomplete.
This
study
examined
effectiveness
of
an
earthing
mat
quality
investigated
underlying
neural
mechanisms
using
electroencephalography
(EEG)
analysis
in
rodents,
focusing
orexin
superoxide
dismutase
(SOD)
levels
brain.
Rats
were
randomly
assigned
four
groups:
naïve
normal
group
(Nor),
exposed
for
7
days
(A-7D),
21
(A-21D),
electronic
blanket
(EM).
EEG
results
revealed
that
A-21D
exhibited
significantly
reduced
wake
time
increased
rapid
eye
movement
(REM),
non-rapid
(NREM),
total
compared
Nor
(p
<
0.05).
Moreover,
demonstrated
significant
increase
NREM
0.001),
REM
0.01),
along
decrease
EM
0.001).
The
level
was
lower
while
SOD1
expression
markedly
elevated
These
suggest
may
represent
promising
new
method
promoting
could
serve
as
effective
technique.
