Heliyon,
Journal Year:
2024,
Volume and Issue:
10(3), P. e24926 - e24926
Published: Feb. 1, 2024
Background
and
aimVitamin
D
deficiency
(VDD)
is
a
global
public
health
problem
in
African
populations.
This
study
aimed
at
determining
the
prevalence,
characteristics,
determinants
of
VDD
era
SARS-CoV-2/COVID-19.
was
conducted
from
January
to
September
2022
seven
facilities
Douala,
Cameroon.MethodsA
structured,
pre-tested
questionnaire
administered
each
participant
collect
participants'
information.
Molecular
detection
SARS-CoV-2
genome
done.
A
serum
level
25-hydroxyvitamin
<
20
ng/mL
used
diagnose
VDD.ResultsA
total
420
participants
were
included
study.
Serum
levels
25(OH)
vitamin
reduced
(+)
patients
as
compared
(-)
(21.69
±
5.64
vs
42.09
20.03
ng/mL,
p
0.0001).
The
overall
prevalence
10.2
%.
individuals
had
nearly
two
times
more
risk
being
(aRR
=
1.81,
by
46
%
71
those
consuming
cocoa
bean
or
powder
regularly
0.54,
0.03)
rarely
0.29,
0.02)
never
it.
Likewise,
59
78
sardine
fish
0.47,
0.002)
0.22,
0.03).
Overall,
association
between
infection
consistent,
i.e.,
individuals,
after
stratification
for
confounding
variables.ConclusionThis
outlined
high
burden
VDD,
strong
link
SARS–CoV–2,
suggests
possible
utility
supplementation
COVID-19
Cameroon.
Frontiers in Medicine,
Journal Year:
2024,
Volume and Issue:
11
Published: Nov. 25, 2024
Objectives
Vitamin
D
has
a
role
in
the
innate
immunity
against
pathogens
and
is
also
involved
mechanisms
for
reducing
inflammation.
VD
deficiency
(VDD)
may
increase
COVID-19
infection
susceptibility,
however
research
limited
on
association
between
VDD
symptom
prevalence
duration.
The
study
aimed
to
determine
whether
risk
factor
presence
extended
duration
of
symptoms.
Methods
Data
was
analyzed
from
NHS
healthcare
workers
who
isolated
due
symptoms
as
part
convalescent
12th
22nd
May
2020.
Participants
self-reported
viral
Anti-SARS-CoV-2
antibodies
vitamin
(25(OH)D
3
)
serum
levels
were
measured
day
recruitment.
defined
25(OH)D
<
30
nmol/l.
Results
Of
392
participants,
15.6%
(
n
=
61)
had
VDD.
participants
more
overall
p
0.0030),
including
body
aches
0.0453),
0.0075)
fatigue
0.0127).
Binary
logistic
regression
found
that
both
(OR
3.069,
95%
CI
1.538–6.124;
0.001)
age
1.026,
1.003–1.049;
0.025)
independently
associated
with
durations
aches.
2.089,
1.087–4.011;
0.027),
1.036,
1.016–1.057;
seroconversion
1.917,
1.203–3.056;
0.006),
fatigue.
Conclusion
significant
independent
supplementation
reduce
thus
an
area
future
research.
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(3), P. e24926 - e24926
Published: Feb. 1, 2024
Background
and
aimVitamin
D
deficiency
(VDD)
is
a
global
public
health
problem
in
African
populations.
This
study
aimed
at
determining
the
prevalence,
characteristics,
determinants
of
VDD
era
SARS-CoV-2/COVID-19.
was
conducted
from
January
to
September
2022
seven
facilities
Douala,
Cameroon.MethodsA
structured,
pre-tested
questionnaire
administered
each
participant
collect
participants'
information.
Molecular
detection
SARS-CoV-2
genome
done.
A
serum
level
25-hydroxyvitamin
<
20
ng/mL
used
diagnose
VDD.ResultsA
total
420
participants
were
included
study.
Serum
levels
25(OH)
vitamin
reduced
(+)
patients
as
compared
(-)
(21.69
±
5.64
vs
42.09
20.03
ng/mL,
p
0.0001).
The
overall
prevalence
10.2
%.
individuals
had
nearly
two
times
more
risk
being
(aRR
=
1.81,
by
46
%
71
those
consuming
cocoa
bean
or
powder
regularly
0.54,
0.03)
rarely
0.29,
0.02)
never
it.
Likewise,
59
78
sardine
fish
0.47,
0.002)
0.22,
0.03).
Overall,
association
between
infection
consistent,
i.e.,
individuals,
after
stratification
for
confounding
variables.ConclusionThis
outlined
high
burden
VDD,
strong
link
SARS–CoV–2,
suggests
possible
utility
supplementation
COVID-19
Cameroon.
