Placental Epigenome Impacts Fetal Development: Effects of Maternal Nutrients and Gut Microbiota
Sanjay Basak,
No information about this author
Rahul Mallick,
No information about this author
Boga Navya Sree
No information about this author
et al.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(12), P. 1860 - 1860
Published: June 13, 2024
Evidence
is
emerging
on
the
role
of
maternal
diet,
gut
microbiota,
and
other
lifestyle
factors
in
establishing
lifelong
health
disease,
which
are
determined
by
transgenerationally
inherited
epigenetic
modifications.
Understanding
mechanisms
may
help
identify
novel
biomarkers
for
gestation-related
exposure,
burden,
or
disease
risk.
Such
essential
developing
tools
early
detection
risk
exposure
levels.
It
necessary
to
establish
an
threshold
due
nutrient
deficiencies
environmental
that
can
result
clinically
relevant
alterations
modulate
risks
fetus.
This
narrative
review
summarizes
latest
updates
roles
nutrients
(n-3
fatty
acids,
polyphenols,
vitamins)
microbiota
placental
epigenome
its
impacts
fetal
brain
development.
unravels
potential
functional
targeted
intervention
ensure
optimal
development
performance
later
life.
Language: Английский
Beyond Nutrition: The Emerging Therapeutic Potential Landscape of Breast Milk-Derived Extracellular Vesicles
Hend Al-Jaber,
No information about this author
Rim Bacha,
No information about this author
Wafaa A Al-Mannai
No information about this author
et al.
Nutrition Research,
Journal Year:
2025,
Volume and Issue:
135, P. 42 - 51
Published: Jan. 14, 2025
Breastfeeding
is
widely
recognized
for
its
essential
nutritional
benefits
and
broader
biological
impacts.
Beyond
providing
infants
with
a
balanced
mix
of
vitamins,
proteins,
fats
critical
growth
development,
breast
milk
contains
bioactive
extracellular
vesicles
(BMEVs).
These
membrane-bound
particles,
rich
in
lipids,
nucleic
acids,
play
pivotal
role
immune
modulation,
intercellular
communication,
the
overall
development
infant's
system.
This
review
explores
emerging
therapeutic
potential
BMEVs,
highlighting
their
capacity
to
modulate
recipient
cell
functions,
influence
responses,
contribute
infant
health.
Preclinical
evidence
suggests
that
these
can
prevent
manage
conditions
such
as
necrotizing
enterocolitis,
allergies,
viral
infections,
which
are
common
early
childhood.
Furthermore,
BMEVs
offer
promise
vehicles
targeted
drug
delivery,
enhancing
efficacy
interventions.
Despite
growing
body
evidence,
challenges
need
standardized
isolation
methods,
characterization
techniques,
larger-scale
clinical
studies
persist,
hindering
translation
this
research
into
practice.
addresses
discusses
future
directions,
emphasizing
comprehensive
mechanistic
fully
realize
novel
agents
biomarkers
Ultimately,
represent
promising
frontier
maternal
child
health,
applications
extending
far
beyond
traditional
nutrition.
By
harnessing
unique
properties,
could
revolutionize
care,
offering
new
strategies
disease
prevention
innovative
interventions
enhance
health
outcomes.
Language: Английский
Current perspectives on perinatal mental health and neurobehavioral development: focus on regulation, coregulation and self-regulation
Current Opinion in Psychiatry,
Journal Year:
2024,
Volume and Issue:
37(3), P. 237 - 250
Published: Feb. 19, 2024
Perinatal
mental
health
research
provides
an
important
perspective
on
neurobehavioral
development.
Here,
we
aim
to
review
the
association
of
maternal
perinatal
with
offspring
neurodevelopment,
providing
update
(self-)regulation
problems,
hypothesized
mechanistic
pathways,
progress
and
challenges,
implications
for
health.
Language: Английский
Placental Epigenome Impacts Fetal Development: Effects of Maternal Nutrients and Gut Microbiota
Sanjay Basak,
No information about this author
Rahul Mallick,
No information about this author
Boga Navyasree
No information about this author
et al.
Published: May 6, 2024
Evidence
is
emerging
on
the
role
of
maternal
diet,
gut
microbiota,
and
other
lifestyle
factors
in
establishing
lifelong
health
disease,
which
are
determined
by
trans-generationally
inherited
epigenetic
modifications.
Understanding
mechanisms
may
help
identify
novel
biomarkers
for
pregnancy-related
exposure,
burden,
or
disease
risk.
Such
essential
developing
tools
early
detection
risk
exposure
levels.
It
necessary
to
establish
threshold
fetus
due
nutrient
deficiencies
environmental
that
can
lead
clinically
relevant
changes
modulate
risks.
This
narrative
review
summarizes
latest
updates
roles
nutrients
(n-3
fatty
acids,
polyphenols,
vitamins)
microbiota
placental
epigenome
its
impacts
fetal
brain
development.
Language: Английский
Exploring the Father’s Role in Determining Neonatal Birth Weight: A Narrative Review
Medicina,
Journal Year:
2024,
Volume and Issue:
60(10), P. 1661 - 1661
Published: Oct. 10, 2024
Birth
weight,
which
exhibits
variability
across
different
populations,
is
influenced
by
a
mix
of
genetic,
environmental,
and
dietary
factors
originating
from
both
the
mother
father.
Maternal
characteristics,
including
age,
socioeconomic
status,
prior
pregnancies,
height,
weight
increase
throughout
pregnancy,
have
substantial
influence
on
fetal
growth
health
infant.
On
other
hand,
paternal
characteristics
newborns
still
not
fully
comprehended
in
consistent
manner.
an
important
factor
that
can
help
predict
various
maternal
complications,
such
as
probability
having
C-section,
experiencing
postpartum
hemorrhage
or
infections.
It
also
indicate
future
challenges
like
asthma,
cognitive
impairment,
chronic
diseases
hypertension
diabetes.
Nineteen
publications
were
found
through
thorough
search
Medline,
PubMed,
Scopus
databases,
provide
insights
into
how
variables
contribute
to
variations
birth
weight.
Significantly,
age
father
was
be
associated
with
higher
chances
preterm
smaller
size
for
gestational
premature
infants,
while
full-term
children
more
likely
larger
age.
In
addition,
there
constant
correlation
between
height
child.
Taller
dads
are
babies
lower
likelihood
being
small
(SGA).
Although
some
discrepancies
data
about
BMI
fathers,
it
fathers
played
significant
role
determining
fetus
newborn.
While
may
differences
conducted
studies,
these
findings
valuable
complex
connection
parental
development.
This
utilized
enhance
clinical
treatment
strategies
our
comprehension
outcomes
neonates.
Further
homogeneous
investigations
required
conclusively
validate
build
upon
findings.
Language: Английский
Impact of Food Insecurity, Undernutrition, and Associate Factors on Pregnant Women: A Review
Published: Dec. 28, 2024
The
health
and
well-being
of
pregnant
women
are
greatly
impacted
by
food
insecurity
undernutrition,
which
can
have
serious
negative
effects
on
both
the
mother
fetus.
purpose
this
review
is
to
investigate
how
affected
insecurity,
related
conditions.
summarizes
previous
research
highlights
important
conclusions
from
investigations
carried
out
in
various
contexts.
Pregnant
worldwide
disproportionately
defined
as
having
inadequate
access
enough
safe,
nourishing
food.
Undernutrition
mothers
raises
risk
unfavorable
outcomes
like
low
birth
weight,
premature
birth,
difficulties
for
mother.
It
caused
consumption,
nutrient
intake,
poor
diet
quality.
Moreover,
exacerbates
confront
because
it
frequently
coexists
with
socioeconomic
inequality,
restricted
healthcare,
weak
social
support
networks.
Food
undernutrition
during
pregnancy
be
a
variety
reasons,
such
cultural
practices,
poverty,
unemployment,
lack
knowledge.
A
comprehensive
strategy
needed
interventions
targeted
at
resolving
these
concerns,
including
protection
programs,
efforts
generate
income,
nutrition
education,
healthcare
services.
poverty
influence
women's
health,
imperative
tackle
intricate
interaction
factors
that
lead
order
enhance
overall
wellbeing
expectant
their
offspring.
Language: Английский