
Food Science of Animal Products, Journal Year: 2024, Volume and Issue: 2(4), P. 9240096 - 9240096
Published: Dec. 1, 2024
Language: Английский
Food Science of Animal Products, Journal Year: 2024, Volume and Issue: 2(4), P. 9240096 - 9240096
Published: Dec. 1, 2024
Language: Английский
Gut Microbes, Journal Year: 2024, Volume and Issue: 16(1)
Published: Nov. 24, 2024
A rising corpus of research has shown the beneficial effects probiotic
Language: Английский
Citations
20Neurobiology of Disease, Journal Year: 2025, Volume and Issue: unknown, P. 106836 - 106836
Published: Feb. 1, 2025
Ischemic stroke (IS) is a cerebrovascular disease that predominantly affects middle-aged and elderly populations, exhibiting high mortality disability rates. At present, the incidence of IS increasing annually, with notable trend towards younger affected individuals. Recent discoveries concerning "gut-brain axis" have established connection between gut brain. Numerous studies revealed intestinal microbes play crucial role in onset, progression, outcomes IS. They are involved entire pathophysiological process through mechanisms such as chronic inflammation, neural regulation, metabolic processes. Although numerous explored relationship microbiota, comprehensive analyses specific microbiota relatively scarce. Therefore, this paper provides an overview typical changes following investigates microorganisms context. Additionally, it presents analysis post-stroke microbiological therapy diet. The aim to identify potential microbial targets for therapeutic intervention, well highlight benefits therapies significance dietary management. Overall, seeks provide key strategies treatment management IS, advocating healthy diets health programs Meanwhile, may offer new perspective on future interdisciplinary development neurology, microbiology nutrition.
Language: Английский
Citations
1Heliyon, Journal Year: 2025, Volume and Issue: 11(4), P. e42719 - e42719
Published: Feb. 1, 2025
Preventing exacerbations in Chronic Obstructive Pulmonary Disease (COPD) is crucial due to the high mortality rate and associated costs of hospitalization for patients during exacerbations. Despite proven influence lung microbiome on disease control, dynamics bacterial communication different stages COPD remain unknown. This study aimed propose a group candidate bacteria differential diagnosis states based relative abundance correlation sputum samples. We compared data collected from 101 stable exacerbation states, as well 124 healthy controls two separate general cohorts, determine major keystone genera. To validate our findings, we utilized additional distinct public datasets, each comprising 81 subjects 87 condition, exacerbation, post-treatment phases. During Porphyromonas, Clostridium, Moryella, Megasphaera were identified phenotype-specific genera, while Prevotella, Streptococcus, Haemophilus, Veillonella consistently present across all datasets core members. Changes genera indicate rewiring interactions, with increased network connectivity observed dysbiosis more severe COPD. Bifidobacterium showed probiotic potential, positively correlating Lactobacillus Neisseria Haemophilus abundance, negatively correlated key bacteria. These findings promising potential simultaneous use along therapeutic prevent health, underscoring need further research future clinical studies.
Language: Английский
Citations
1Critical Reviews in Food Science and Nutrition, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 21
Published: June 26, 2024
(
Citations
4Microorganisms, Journal Year: 2025, Volume and Issue: 13(2), P. 239 - 239
Published: Jan. 22, 2025
Lactic acid bacteria play a crucial role in maintaining the health of host’s gut microbiota. In this study, anti-inflammatory properties Limosilactobacillus reuteri LR20-6 and Lacticplantibacillus plantarum L272 were evaluated using mouse model diarrhea induced by Escherichia coli. We also investigated their effects on microbiota regulation. The results indicated that both could reduce inflammation inhibiting expression inflammatory factors IL-6 TNF-α blocking MyD88 NF-kB/p65 signaling pathways. Additionally, after intervention with these strains, relative abundance Lactobacillus was significantly increased. This suggested mitigate severity E. coli-induced enhance beneficial probiotics animals.
Language: Английский
Citations
0European Journal of Nutrition, Journal Year: 2025, Volume and Issue: 64(2)
Published: Feb. 11, 2025
Language: Английский
Citations
0Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106429 - 106429
Published: March 1, 2025
Language: Английский
Citations
0Probiotics and Antimicrobial Proteins, Journal Year: 2025, Volume and Issue: unknown
Published: April 26, 2025
Spinal cord injury (SCI) disrupts gut flora and exacerbates neuroinflammation. Evidence supports the important role of intestinal microbiota in SCI. This study evaluated neuroprotective effect Limosilactobacillus reuteri (L. reuteri) DSM 17938 on SCI its potential anti-inflammatory mechanism. The was disorganised following SCI, with a significant decrease abundance probiotic bacteria such as L. reuteri. DSM17938 treatment improved spinal pathology enhanced locomotor functional recovery SCI-model rats. Moreover, it modulated tryptophan metabolism by promoting indole-3-carboxaldehyde production. In addition, inhibits polarization M1 microglia reduces production IL-6, IL-1 β, TNF-α to alleviate It also activates aryl hydrocarbon receptor (AhR) signalling via upregulating AhR CYP1A1 expression, tight junction protein synthesis. summary, promotes modulating activate barrier repair attenuate microglial activation neuroinflammation, suggesting strategy for clinical adjuvant treatment.
Language: Английский
Citations
0Pharmacology Biochemistry and Behavior, Journal Year: 2024, Volume and Issue: 245, P. 173880 - 173880
Published: Sept. 14, 2024
Language: Английский
Citations
0Journal of Thoracic Disease, Journal Year: 2024, Volume and Issue: 16(10), P. 6835 - 6848
Published: Oct. 1, 2024
Seawater drowning is a leading cause of accidental injury and death, the resulting acute lung (ALI) serious clinical syndrome for which there are no effective treatments. This study aims to investigate potential mechanism seawater drowning-induced ALI.
Language: Английский
Citations
0