Anticancer Potential of Pineapple and its Bioactive Compound Bromelain DOI

Davinder Kumar,

Suchitra Suchitra,

Jyoti Mundlia

et al.

Current Pharmaceutical Design, Journal Year: 2024, Volume and Issue: 31(6), P. 461 - 483

Published: Sept. 16, 2024

Various ailments have been treated with pineapple (<i>Ananas comosus</i> (L.) Merr.) throughout medicinal history. Pineapple and its bioactive compound bromelain possess health-promoting benefits. Detailed information on the chemotherapeutic activities of is provided in this review, which analyses current literature regarding their therapeutic potential cancer. Research disease models cell cultures focus much existing research. Several studies demonstrated benefits extract for vitro vivo cancer models. Preliminary animal model results show promise, but they must be translated into clinical setting. these compounds represents a promising future direction may well-tolerated.

Language: Английский

Exploring the Anti-Colon Cancer Potential of Polygonum minus: Integrating In Vitro and In Silico Studies DOI
Zhongming Yang, Zhongguo Yang,

Md Zuki Abu Bakar

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: 64, P. 105853 - 105853

Published: Jan. 6, 2025

Language: Английский

Citations

3
Ethnobotanical survey of medicinal plants used in management of Breast cancers in Qatar DOI Creative Commons
Rasha S.Abo El Alaa, Hend Al-Jaber,

Fatima Al Zahraa Chokor

et al.

Heliyon, Journal Year: 2025, Volume and Issue: 11(4), P. e42541 - e42541

Published: Feb. 1, 2025

Highlights•Ethnobotanical Survey documented the practices of 13 herbalists in Doha, Qatar, revealing use various plant species for breast cancer treatment, with Saussurea costus (Falc.) Lipsch. (Al Qist Al Hindi), Zingiber officinale Roscoe (Ginger) (zanjabel) and Nigella sativa L. (Black seeds) (habit elbaraka being most recommended.•Herbal medicine is widely used by patients Qatar as a supplement to conventional treatments, driven traditional social influences.•Literature review corroborated anticancer potential recommended plants, many which induce apoptosis have progressed clinical studies.•The study highlights integrating herbal modern enhance management Qatar.Abstract:Breast global health concern, including where it impacts women significantly. The complexity requires diverse treatment approaches influenced tumor characteristics biology. Despite advancements, current treatments still fall short providing definitive solutions, particularly triple-negative cancer. Complementary Alternative Medicine (CAM), remedies, increasingly popular among patients, those Qatar. In population, yet preserving this knowledge faces significant challenges. This aimed document herbalists' ethnobotanical concerning corroborate any identified remedies' literature. Thirteen were surveyed using an questionnaire between October November 2022. Herbalists' demographic data their recommendations collected through structured interviews. Descriptive statistics Relative Frequency Citation (RFC) employed analysis. validate plants existing present regarding from ten different families. elbaraka) plants.Literature searches revealed that these possess compounds properties sesquiterpenes, flavonoids, thymoquinone, volatile terpenic anthocyanin. sources primarily India Iran due historical trade relations Herbalists predominantly underground parts but could consider leaves proven properties. Each reported was scrutinized its potential, collecting published research about uses, cytotoxicity against cells. literature survey also uncovered are specific pathways, while others showed chemo-sensitization effects cancer-induced mutation prevention. Moreover, some advanced studies. Beyond cancer, displayed promise addressing diabetes inflammation. conclusion, our on documents patient therapy Hindi) emerged commonly prescribed plant, roots used. Overall, findings describe handling offer insights into enhanced management.

Language: Английский

Citations

0
Unravelling the epigenetic based mechanism in discovery of anticancer phytomedicine: Evidence based studies DOI
Bushra Bashir, Pranshul Sethi,

Satyajit Panda

et al.

Cellular Signalling, Journal Year: 2025, Volume and Issue: unknown, P. 111743 - 111743

Published: March 1, 2025

Language: Английский

Citations

0
Novel Erodium glaucophyllum (L.) Aiton growing in arid environment: Phytochemical characterization, antimicrobial, antioxidant, and anticancer potential DOI Creative Commons
Amr H. Hashem, Bahaa Badr, Fathy M. Elkady

et al.

Electronic Journal of Biotechnology, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0
Anticancer Potential of Pineapple and its Bioactive Compound Bromelain DOI

Davinder Kumar,

Suchitra Suchitra,

Jyoti Mundlia

et al.

Current Pharmaceutical Design, Journal Year: 2024, Volume and Issue: 31(6), P. 461 - 483

Published: Sept. 16, 2024

Various ailments have been treated with pineapple (<i>Ananas comosus</i> (L.) Merr.) throughout medicinal history. Pineapple and its bioactive compound bromelain possess health-promoting benefits. Detailed information on the chemotherapeutic activities of is provided in this review, which analyses current literature regarding their therapeutic potential cancer. Research disease models cell cultures focus much existing research. Several studies demonstrated benefits extract for vitro vivo cancer models. Preliminary animal model results show promise, but they must be translated into clinical setting. these compounds represents a promising future direction may well-tolerated.

Language: Английский

Citations

0