Ketogenic diet for ovarian disorders - promising nutritional approach in polycystic ovarian syndrome and ovarian cancer DOI Creative Commons
Magda Wojtuś, Sebastian Tomaszuk, Karolina Wąsik

et al.

Journal of Education Health and Sport, Journal Year: 2024, Volume and Issue: 65, P. 49846 - 49846

Published: April 12, 2024

Introduction and purpose: Polycystic ovary syndrome (PCOS) is the most common endocrine disease in female reproductive age. As treatment guidelines include lifestyle changes, various diet types are being evaluated terms of efficacy among them ketogenic (KD) which was also assessed its influence on another ovarian related - cancer. The aim this paper an analysis available scientific data respect role KD as a part therapy disorders. search conducted using PubMed Google Scholarship databases. Brief description state knowledge: Ketogenic demonstrates favorable effects hormonal profile PCOS-affected women. It noticed that administration results reduction BMI improvement glycemic parameters. Most research by linking with caloric restriction. In matter cancer unclear; some states quality life participants, but there alarming possible enhancing tumor growth. Conclusions: merits further factor PCOS foregoing pointing to efficacy. Nevertheless, still more needed determine studies were within short period time relatively small groups. There other limitations such lack comparison dietary patterns deficit makes it difficult deduce main profitable factor. When comes current unclear unambiguous negative effects.

Language: Английский

Nutritional Studies Evaluating Ketogenic Diets as a Treatment for Obesity and Obesity-Associated Morbidities: Underlying Mechanisms and Potential for Clinical Implementation DOI Creative Commons
Luciano Pirola, Karolina Maria Górecka, Carol Góis Leandro

et al.

Endocrines, Journal Year: 2024, Volume and Issue: 5(4), P. 585 - 599

Published: Dec. 3, 2024

Background: The ketogenic diet (KD), characterized by high-fat content, virtually no carbohydrates, and adequate protein intake, induces a metabolic state resembling fasting, as the absence of carbohydrates forces body to rely on energetic supply from hepatically produced ketone bodies using free fatty acids substrate. While KD is clinically used in pharmacologically refractory epilepsy specific genetic conditions such GLUT1 deficiency, recent research suggests that, due its “fasting mimicking” properties, may also beneficially affect obesity obesity-associated diseases. Results: Here, we present narrative review discussing completed ongoing nutritional studies human volunteers specifically addressing potential an anti-obesity approach and, larger perspective, intervention ameliorate type 1 2 diabetes polycystic ovary syndrome (PCOS). Published well clinical trials will be discussed. Efficacy safety considerations discussed, physiological mechanisms mediating effects humans context (i) energy balance model (EBM) (ii) carbohydrate–insulin (CIM) weight control. Conclusion: Ketogenic diets beneficial attenuate improve obesity-related disease, here, try, based current evidence, define boundaries KD’s usefulness.

Language: Английский

Citations

1
Impact of short‐term ketogenic diet on sex hormones and glucose‐lipid metabolism in overweight or obese patients with polycystic ovary syndrome DOI Open Access

Meng Li,

Lisong Zhang, Xiaoyu Li

et al.

Journal of Obstetrics and Gynaecology Research, Journal Year: 2024, Volume and Issue: 51(1)

Published: Dec. 11, 2024

This study evaluates the clinical effects of a ketogenic diet (KD) versus traditional comprehensive intervention, including lifestyle changes and oral contraceptives, in overweight or obese polycystic ovary syndrome (PCOS) patients.

Language: Английский

Citations

1
Ketogenic diet for ovarian disorders - promising nutritional approach in polycystic ovarian syndrome and ovarian cancer DOI Creative Commons
Magda Wojtuś, Sebastian Tomaszuk, Karolina Wąsik

et al.

Journal of Education Health and Sport, Journal Year: 2024, Volume and Issue: 65, P. 49846 - 49846

Published: April 12, 2024

Introduction and purpose: Polycystic ovary syndrome (PCOS) is the most common endocrine disease in female reproductive age. As treatment guidelines include lifestyle changes, various diet types are being evaluated terms of efficacy among them ketogenic (KD) which was also assessed its influence on another ovarian related - cancer. The aim this paper an analysis available scientific data respect role KD as a part therapy disorders. search conducted using PubMed Google Scholarship databases. Brief description state knowledge: Ketogenic demonstrates favorable effects hormonal profile PCOS-affected women. It noticed that administration results reduction BMI improvement glycemic parameters. Most research by linking with caloric restriction. In matter cancer unclear; some states quality life participants, but there alarming possible enhancing tumor growth. Conclusions: merits further factor PCOS foregoing pointing to efficacy. Nevertheless, still more needed determine studies were within short period time relatively small groups. There other limitations such lack comparison dietary patterns deficit makes it difficult deduce main profitable factor. When comes current unclear unambiguous negative effects.

Language: Английский

Citations

0