Exploring the Potential of Bambara Groundnut Flour as an Alternative for Diabetic and Obese Patients in the USA: A Comprehensive Review

Cureus, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 30, 2025

Bambara groundnut flour (BGNF), derived from Vigna subterranea, is a nutrient-dense, low-glycemic alternative to traditional flours, making it beneficial for diabetes and obesity management. Rich in protein (18-24%) fiber (12-19%), promotes satiety, regulates blood sugar, supports muscle preservation during weight loss. Its complex carbohydrates resistant starch allow gradual glucose release, reducing sugar spikes diabetics. BGNF also contains antioxidants anti-inflammatory compounds that may help mitigate diabetes-related complications. Compared almond, coconut, chickpea offers balanced nutrient profile suitable glycemic control However, challenges such as limited production, high costs, low public awareness hinder its accessibility, particularly the U.S. To fully realize potential, research, including clinical trials, needed validate health benefits, while efforts scale production raise could position sustainable, functional food managing chronic conditions.

Language: Английский

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Triglyceride-glucose index in adolescents with type 1 diabetes mellitus

Diabetes Research and Clinical Practice, Journal Year: 2025, Volume and Issue: unknown, P. 112048 - 112048

Published: Feb. 1, 2025

Language: Английский

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Associations between children’s dietary patterns, excessive weight gain, and obesity risk: cohort study nested to a randomized field trial

Revista Paulista de Pediatria, Journal Year: 2025, Volume and Issue: 43

Published: Jan. 1, 2025

ABSTRACT Objective To identify the critical period of excessive weight gain (EWG) in childhood and dietary patterns associated with it. Methods A cohort study nested to a randomized field trial mother-child pairs interviewed by home visits at ages six months, 12 three years, years. We selected 715 pregnant women from 20 healthcare centers southern Brazil. EWG was considered as change body mass index-for-age (BMI-for-age) z-score >0.67. Two 24-hour recalls were used determine exploratory factor analysis. The effect on assessed logistic regressions using Generalized Estimating Equations. Results for months (46.5% BMI variation >0.67; n=228; p≤0.001). Dietary baby bottles cow´s milk added cereal flours sugar (relative risk – RR 1.43; 95% confidence interval 95%CI 1.15–1.79; p≤0.001 1.59; 1.28–1.97, p≤0.001); fruit juice creamy dessert (RR 1.39; 1.08–1.33; p≤0.001) sweet beverages 1.19; 1.02–1.38; p=0.024). Conclusions second semester life most childhood, influenced mostly consumption cow’s flour sugar, juice, desserts, beverages. These findings emphasize importance early interventions promote healthier food choices prevent during infancy.

Language: Английский

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New concepts in the roles of AMPK in adipocyte stem cell biology

Essays in Biochemistry, Journal Year: 2024, Volume and Issue: 68(3), P. 349 - 361

Published: Aug. 23, 2024

Abstract Obesity is a major risk factor for many life-threatening diseases. Adipose tissue dysfunction emerging as driving in the transition from excess adiposity to comorbidities such metabolic-associated fatty liver disease, cardiovascular Type 2 diabetes and cancer. However, healthy adipose expansion development of these conditions poorly understood. stem cells, residing vasculature stromal regions subcutaneous visceral depots, are responsible maintenance organ function, now recognised key mediators pathological transformation. Impaired drives inflammation, dysregulation endocrine function deposition lipids liver, muscle around vital organs, where it toxic. Contrary previous hypotheses, promotion not inhibition adipogenesis, that presents most attractive therapeutic strategy treatment metabolic disease. AMP-activated protein kinase, master regulator energy homeostasis, has been regarded one target, due its central role lipid metabolism, apparent adipogenesis. recent studies utilising kinase (AMPK)-specific compounds highlight more subtle, time-dependent AMPK process previously unexplored repression leptin, independent adipocyte maturity. In this article, I discuss historic evidence AMPK-mediated adipogenesis multi-faceted roles tissue.

Language: Английский

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Insights in Nutrition to Optimize Type 1 Diabetes Therapy

Nutrients, Journal Year: 2024, Volume and Issue: 16(21), P. 3639 - 3639

Published: Oct. 26, 2024

Nutrition is an essential part of therapy for type 1 diabetes and constantly evolving, offering growing opportunities to prevent this disease, slow down its evolution, mitigate it. An attempt was made bring together the current state knowledge. In path from preclinical phase disease clinical onset, there a known as “honeymoon period” or partial remission, where different possible dietary options combatting have been presented. The most commonly used models were compared, frequent co-existing pathologies, such overweight, non-alcoholic fatty liver dyslipidemia, celiac metabolic instability, addressed their nutritional perspectives provide clinicians with updated framework knowledge support researchers in further investigations into topic. Finally, glimpse interplay between nutrition gut microbiome, food security, ultra-processed provided. It hoped that treating people will be provided daily management patients through personalized nutrition.

Language: Английский

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