Impact of Pomegranate Extract Supplementation on Physical and Cognitive Function in Community-Dwelling Older Adults Aged 55–70 Years: A Randomised Double-Blind Clinical Trial
Geriatrics,
Journal Year:
2025,
Volume and Issue:
10(1), P. 29 - 29
Published: Feb. 17, 2025
Background/objectives:
Cognitive
decline
and
loss
of
physical
function
are
common
concerns
in
older
adults,
with
limited
effective
interventions
available.
This
study
aimed
to
assess
the
impact
pomegranate
extract
(PE)
supplementation
on
cognitive
adults
aged
55-70
years.
Methods:
A
randomised,
double-blind
placebo-controlled
trial
was
conducted
86
participants,
who
were
assigned
receive
either
PE
(740
mg)
or
a
placebo
(maltodextrin)
daily
for
12
weeks.
assessed
using
computerised
tests
(Corsi,
digit
span,
Wisconsin
Card
Sorting
Test
(WCST),
Tower
Hanoi,
Stroop
test
Rey
auditory
verbal
learning
test).
Physical
measured
through
assessments
standing
balance,
gait
speed,
chair
sit
stand
grip
strength.
Results:
There
significant
effect
treatment
time
WCST
performance
(F
(1,2)
=
2.718,
p
0.05),
while
trends
towards
better
outcomes
group
noted
Hanoi
tests.
did
not
seem
be
affected
by
intervention,
but
results
may
have
been
high
baseline
activity
levels
full
mobility
adults.
Conclusions:
first
examine
over
duration
Findings
suggest
that
has
potential
improving
offer
promising
approach
preventing
ageing
Further
controlled
well-designed
long-term
studies
needed
establish
effects
health,
along
mechanisms
action
involved.
Language: Английский
A novel ultrasound-assisted enzyme extraction method of total flavonoids from Viticis Fructus and processed Viticis Fructus: Comparison of in vitro antioxidant activity
Yuman Li,
No information about this author
Qing Zhang,
No information about this author
Qi Fang
No information about this author
et al.
Ultrasonics Sonochemistry,
Journal Year:
2024,
Volume and Issue:
110, P. 107045 - 107045
Published: Aug. 24, 2024
In
this
study,
it
is
the
first
that
Viticis
Fructus
(VF)
was
used
as
raw
material
for
extracting
total
flavonoids
using
ultrasound-assisted
enzyme
extraction
(UAE)
method.
Response
surface
methodology
employed
to
determine
optimal
parameters.
The
conditions
were
follows:
60
%
ethanol
solution
extract
solvent,
material-liquid
ratio
of
1:25,
pH
value
4,
addition
amount
1.5
%,
enzymatic
hydrolysis
time
30
min,
temperature
40
℃,
and
ultrasonic
50
min.
Comparing
flavonoid
yield
VF
processed
(PVF)
extracted
different
methods,
observed
UAE
resulted
in
a
higher
compared
traditional
ultrasound
extraction.
Additionally,
PVF
by
all
three
methods
generally
than
VF.
also
demonstrated
better
vitro
antioxidant
activity
These
results
suggest
an
effective
method
enhance
natural
flavonoids.
study
physicochemical
properties
showed
significantly
increased
after
stir-frying,
indicating
their
efficacy
can
be
enhanced.
Language: Английский
Bacterial nanocellulose and its oxidized form as functional carriers for pomegranate peel extract: A sustainable approach to bioactive delivery
Future Foods,
Journal Year:
2025,
Volume and Issue:
unknown, P. 100560 - 100560
Published: Feb. 1, 2025
Language: Английский
Phytochemicals and pharmacology of pomegranate (Punica granatum L.): nutraceutical benefits and industrial applications: a review
Sana Noreen,
No information about this author
Bushra Hashmi,
No information about this author
Patrick Maduabuchi Aja
No information about this author
et al.
Frontiers in Nutrition,
Journal Year:
2025,
Volume and Issue:
12
Published: March 27, 2025
Introduction
Pomegranate
(
Punica
granatum
L.)
is
a
fruit
native
to
South
Asia
and
currently
can
grow
in
tropical
subtropical
areas,
which
produces
approximately
seven
thousand
metric
tons
per
year.
stands
out
for
its
rich
flavor
functional
properties,
why
it
has
gained
acceptance
different
countries.
Beyond
health
advantages,
industrial
applications
food
technology,
cosmetics,
medicines.
This
study
focuses
on
diverse
phytochemical
profile
the
medicinal
properties
of
bioactive
components.
Methods
A
search
PubMed,
Scopus,
EBSCO,
Medline,
Embase,
SID,
Iran
Medex
databases
was
conducted
identify
clinical
observational
studies
consumption
uses.
Results
by-products
are
beneficial
phytochemicals,
provide
benefits,
help
manage
ailments.
Sustainable
reuse
supports
health,
economic
growth,
security.
Conclusion
including
antidiabetic,
antioxidant,
anticancer,
anti-inflammatory
effects,
with
potential
product
development
disease
management.
Analyzing
pomegranate's
nutritional
especially
peel
seed,
crucial
understanding
mechanisms
involved
processes
nutraceutical
or
products.
Language: Английский
Pomegranate (Punica granatum L.) Extract Effects on Inflammaging
Molecules,
Journal Year:
2024,
Volume and Issue:
29(17), P. 4174 - 4174
Published: Sept. 3, 2024
Pomegranate
is
a
notable
source
of
nutrients,
containing
considerable
proportion
organic
acids,
polysaccharides,
vitamins,
fatty
and
polyphenols
such
as
flavonoids,
phenolic
tannins.
It
also
rich
in
nutritionally
important
minerals
chemical
elements
K,
P,
Na,
Ca,
Mg,
N.
The
presence
several
bioactive
compounds
metabolites
pomegranate
has
led
to
its
incorporation
into
the
functional
food
category,
where
it
used
for
numerous
therapeutic
properties.
Pomegranate’s
have
shown
antioxidant,
anti-inflammatory,
anticancer
effects.
Aging
process
characterized
by
chronic
accumulation
damages,
progressively
compromising
cells,
tissues,
organs
over
time.
Inflammaging
chronic,
subclinical,
low-grade
inflammation
that
occurs
during
aging
linked
many
age-related
diseases.
This
review
aims
summarize
discuss
evidence
benefits
extract
slow
processes
intervening
mechanisms
underlying
inflammaging.
These
studies
mainly
concern
neurodegenerative
skin
diseases,
while
other
fields
application
need
be
more
practical.
Furthermore,
no
human
demonstrated
anti-inflammaging
effects
pomegranate.
In
future,
supplementation
with
extracts,
polyphenols,
or
urolithins
could
represent
valuable
low-risk
complementary
therapy
patients
difficult-to-manage
well
valid
alternative
topical
systemic
treatment
pathologies.
Language: Английский
Sustainable Extraction Protocols for the Recovery of Bioactive Compounds from By-Products of Pomegranate Fruit Processing
Foods,
Journal Year:
2024,
Volume and Issue:
13(12), P. 1793 - 1793
Published: June 7, 2024
This
study
investigates
sustainable
extraction
protocols
for
the
recovery
of
bioactive
compounds
from
by-products
various
pomegranate
(
Language: Английский
Hydrodynamic cavitation as a promising technology for fresh produce-based beverages processing
Innovative Food Science & Emerging Technologies,
Journal Year:
2024,
Volume and Issue:
96, P. 103784 - 103784
Published: Aug. 1, 2024
Language: Английский
Review of novel techniques for extracting phytochemical compounds from pomegranate (Punica granatum L.) peel using a combination of different methods
Yadhav PM,
No information about this author
Sonia Morya,
No information about this author
Maanas Sharma
No information about this author
et al.
Biomass Conversion and Biorefinery,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 7, 2024
Language: Английский
Effects of sour cherry fruits on platelet aggregation and arterialblood pressure
Shamilyan Knarik,
No information about this author
Topchyan Hakob,
No information about this author
Zhamharyan Arusyak
No information about this author
et al.
Functional Foods in Health and Disease,
Journal Year:
2024,
Volume and Issue:
14(8), P. 630 - 638
Published: Aug. 30, 2024
Background:
The
pivotal
roles
that
platelet
aggregation
and
hypertension
play
in
the
pathogenesis
of
ischemic
disorders
have
emphasized
importance
antiplatelet
antihypertensive
agents
treatment
cardiovascular
cerebrovascular
diseases,
leading
causes
disability
worldwide.
Despite
abundance
these
drug
groups,
finding
new
with
fewer
side
effects
complications
continues
to
be
an
important
mission
modern
medicine.
To
combat
adverse
manufactured
medications,
plants
could
promising
sources
for
remedies.
One
such
plant,
Sour
Cherry,
can
serve
as
a
source
medications
considering
its
rich
content
anthocyanins,
flavonoids,
organic
acids.
Objectives:
purpose
this
study
was
investigate
Armenian
Cherries.
Results:
It
has
been
revealed
Cherries
contain
properties
incorporated
into
Conducted
observation
shows
after
3
hours
Cherry
intake,
amplitude
(A6)
reduced
by
40.2±17.21%
(p<0.05),
maximal
slope
41.1±14.6%
(p<0.05,)
area
under
curve
50.3±19.75%
(p<0.05)
comparison
negative
control.
Measuring
same
indicators
5
demonstrated
effect
on
process
inferior
compared
3rd
hour
data,
remaining
less
than
characteristics
After
reduction
amplitude,
maximum
control,
were
29.84±8.27%
39.29
±11.74%
36.18±19.13%
respectively.
investigation
Cherries’
animals’
blood
pressures
demonstrates
intraperitoneal
injection
freeze-dried
solution
accompanied
changes
pressure
heart
rates.
Systolic
values
administration
fruits
began
reducing
from
10th
minute
experiment
reached
at
40th
15.3%.
minute,
tendency
recovery
systolic
values,
which
remained
0hour
even
90th
experiment,
registered.
Maximum
(14.2
%)
diastolic
takes
place
20thminute
control
until
experiment.
Calculations
mean
arterial
similar
tendency.
Heart
rate
followed
fall
pressure,
increasing
27.7
beats
per
50th
Conclusion:
presented
proves
functional
foods
opens
up
perspectives
search
new,
safe
prevention
diseases
stroke
based
food
properties.
This
obtained
data
platform
development
dosage
form
possibility
highly
preserved
biologically
active
substances.
Keywords:
cherry
fruits,
activity,
action
Language: Английский
1H-NMR, HPSEC-RID, and HPAEC-PAD Characterization of Polysaccharides Extracted by Hydrodynamic Cavitation from Apple and Pomegranate By-Products for Their Valorization: A Focus on Pectin
Processes,
Journal Year:
2024,
Volume and Issue:
12(10), P. 2113 - 2113
Published: Sept. 28, 2024
Several
chemical
analytical
methods
were
applied
to
characterize
the
structure
of
polysaccharides
extracted
from
discarded
apples
and
pomegranate
peels
using
hydrodynamic
cavitation
in
a
circular
economy
perspective.
In
particular,
purity
degrees
acetylation
methylation
evaluated
by
proton
Nuclear
Magnetic
Resonance
(1H-NMR)
analysis;
simple
sugars
galacturonic
acid
analyzed
simultaneously
High-Performance
Anion
Exchange
Chromatography—Pulsed
Amperometric
Detector
(HPAEC-PAD);
molecular
weight
was
determined
Size
Exclusion
Chromatography-Refractive
Index
(HPSEC-RID).
The
results
showed
negligible
presence
co-precipitated
proteins/tannins,
easily
removed
dialysis,
as
well
other
molecules
such
monosaccharides
organic
acids.
Polysaccharides
consisted
mainly
pectic
material
with
prevalence
homogalacturonans.
greater
compositional
variability
significant
amounts
arabinose
galactose,
lower
content
pectin,
rhamnogalacturonans
I.
Both
highly
methylated
differed
degree
acetylation,
which
could
lead
different
properties.
presented
two
main
weights
(>805
kDa
348–805
kDa,
respectively),
while
those
peel
major
fraction
at
348
minor
fractions
<
23
kDa.
conclusion,
research
tools
proposed
this
study
have
allowed
defining
macrostructure
quick
efficient
way
valorize
these
food
by-products.
Language: Английский