Association between demographic, clinical characteristics and severe complications by SARS-CoV-2 infection in a community-based healthcare network in Chile DOI Creative Commons
Javiera Léniz, Sam Hernández-Jaña, Mauricio Soto

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(12), P. e0314376 - e0314376

Published: Dec. 30, 2024

Background Most of the evidence on risk factors for COVID-19 complications comes from North America or Europe with very little research Latin-America. We aimed to evaluate association between sociodemographic, clinical and among adults in Chile, fifth Latin-American country more reported cases since de beginning Pandemic. Methods A retrospective population-based cohort study using data electronic health records a large Primary Care Network, linked national hospital, immunization, Covid-19 PCR surveillance, mortality birth records. included people 18+ years old enrolled Network 1 st January 2020 31 December 2021. Using Multivariate Cox proportional hazard models, we characteristics three complications: (1) hospital admission, (2) an ICU (3) death due infection that occurred Results 44,674 were included. The mean age was 44.30 (sd 17.31), 55.6% female, 15.9% had type healthcare insurance lowest category income, 11.6% 9.4% record hypertension diabetes mellitus diagnosis. Among people, 455 (1.02%) admission 216(0.48%) them also admission. people,148(0.33%) died infection. Older male sex consistently associated higher complications. Hypertension death, but not admissions Having two vaccine doses compared no lower any (HR 0.81; 95% CI 0.77–0.84), 0.60; 0.57–0.63) 0.50; 0.46–0.54). Pregnant puerperal women likely be admitted 2.89; 1.41–5.89) 3.04; 1.01–9.14). Conclusions Sociodemographic such as age, pre-existing conditions comparable those similar studies higher-income countries, can used predict severity patients.

Language: Английский

Safety and immunogenicity of CoronaVac and ChAdOx1 heterologous prime-boost vaccines in an overweight population in Chiang Mai, Thailand DOI Creative Commons
Kriangkrai Chawansuntati, Supachai Sakkhachornphop, Sayamon Hongjaisee

et al.

Vaccine X, Journal Year: 2024, Volume and Issue: 18, P. 100475 - 100475

Published: March 16, 2024

In early 2021, the Ministry of Public Health Thailand announced heterologous regimens for COVID-19 vaccines using CoronaVac as first dose followed by ChAdOx1 nCoV-19 at 3 weeks apart. Priority was given to individuals above 60 years old and those who had seven underlying conditions, including obesity. The vaccine regimen evaluated safety immunogenicity in overweight populations Chiang Mai, Thailand. Participants a vaccination appointment prime-boost were enrolled. Before each immunization on day 28 following second dosage, blood samples taken, examined anti-spike neutralizing antibodies an indirect ELISA virus neutralization assays. Safety profile assessed via self-recorded diary adverse events after vaccination. No serious related reported during study period majority reactions fatigue pain injection site. levels IgG 26.3, 56.4 1752.1 BAU/mL baseline, 21 days dose, respectively. At 4 complete vaccination, median inhibition rates antibody determined surrogate assay against wild type, Delta Omicron variants 95.2, 85.0 3.8, Moreover, NT50 level type pseudotyped 133.3 41.7, activity variant almost lower than cutoff detection. CoronaVac-ChAdOx1vaccination safe, well-tolerated able induce humoral immunity wild-type but not population.

Language: Английский

Citations

0
Análisis del Vínculo de Usuarios de Distintas Unidades Básicas de Salud Con Posible Diagnóstico de Enfermedades Crónicas no Transmisibles Frente a la Pandemia del Covid-19 en el en una ciudad del sur de Brasil DOI Creative Commons
Virgínia B. Nanuncio-Capucho, Regiane de Paula,

Letícia de-Almeida

et al.

Ciencias de la actividad física, Journal Year: 2024, Volume and Issue: 25(1), P. 1 - 14

Published: Jan. 1, 2024

Non-communicable chronic diseases (NCDs) are considered one of the leading causes death worldwide. During COVID-19 pandemic, these have been neglected due to Brazilian Unified National Health System (BHUS) overload. In this context, study aimed analyze bond between patients with NCDs and primary care during pandemic while also seeking identify population's level knowledge about health parameters their relationship healthcare system. A cross-sectional observational was conducted, in which an online questionnaire administered collect socioeconomic information from BHUS metropolitan region Maringa, Parana, Brazil, encompassing individuals over 18 years age. The survey promoted on social media, interested participants responded questionnaire, addressed topics such as identification, medication use, disease information, NCDs, general data related COVID-19. obtained analyzed responses revealed a low population lack pandemic. There notable decrease services period, may be explained by fear contracting novel coronavirus. This is essential understand patients' public challenges It can become valuable ally dealing future pandemics endemic crises, enabling improvements raising awareness among

Language: Английский

Citations

0
Impact of Multi-Professional Intervention on Health-Related Physical Fitness and Biomarkers in Overweight COVID-19 Survivors for 8 and 16 Weeks: A Non-Randomized Clinical Trial DOI Open Access
Marielle Priscila de Paula Silva Lalucci, Déborah Cristina de Souza Marques, Joed Jacinto Ryal

et al.

Healthcare, Journal Year: 2024, Volume and Issue: 12(20), P. 2034 - 2034

Published: Oct. 14, 2024

Considering the diverse symptomatology of COVID-19-ranging from mild to severe cases-multi-professional interventions are crucial for enhancing physical recovery, nutritional status, and mental health outcomes in affected patients. Thus, this study aimed investigate effects such an intervention on health-related fitness biomarkers overweight COVID-19 survivors with varying degrees symptom severity after 8 weeks 16 weeks.

Language: Английский

Citations

0
Association between demographic, clinical characteristics and severe complications by SARS-CoV-2 infection in a community-based healthcare network in Chile DOI Creative Commons
Javiera Léniz, Sam Hernández-Jaña, Mauricio Soto

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(12), P. e0314376 - e0314376

Published: Dec. 30, 2024

Background Most of the evidence on risk factors for COVID-19 complications comes from North America or Europe with very little research Latin-America. We aimed to evaluate association between sociodemographic, clinical and among adults in Chile, fifth Latin-American country more reported cases since de beginning Pandemic. Methods A retrospective population-based cohort study using data electronic health records a large Primary Care Network, linked national hospital, immunization, Covid-19 PCR surveillance, mortality birth records. included people 18+ years old enrolled Network 1 st January 2020 31 December 2021. Using Multivariate Cox proportional hazard models, we characteristics three complications: (1) hospital admission, (2) an ICU (3) death due infection that occurred Results 44,674 were included. The mean age was 44.30 (sd 17.31), 55.6% female, 15.9% had type healthcare insurance lowest category income, 11.6% 9.4% record hypertension diabetes mellitus diagnosis. Among people, 455 (1.02%) admission 216(0.48%) them also admission. people,148(0.33%) died infection. Older male sex consistently associated higher complications. Hypertension death, but not admissions Having two vaccine doses compared no lower any (HR 0.81; 95% CI 0.77–0.84), 0.60; 0.57–0.63) 0.50; 0.46–0.54). Pregnant puerperal women likely be admitted 2.89; 1.41–5.89) 3.04; 1.01–9.14). Conclusions Sociodemographic such as age, pre-existing conditions comparable those similar studies higher-income countries, can used predict severity patients.

Language: Английский

Citations

0