Mediation Role of Telomere Length in the Relationship between Physical Activity and PhenoAge: A Population-based Study DOI Creative Commons
Yanwei You,

Dizhi Wang,

Hao Ding

et al.

Journal of Exercise Science & Fitness, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

The relationship between physical activity (PA), telomere length, and phenotypic age (PhenoAge) represents a pivotal area of investigation in aging research. study encompassed cohort 6200 participants aged 20 years above, sourced from the National Health Nutrition Examination Survey (NHANES). Physical (PA) levels were assessed employing Global Activity Questionnaire, while DNA samples collected to determine measured base pairs. PhenoAge, an emerging index relying on nine distinct chemical biomarkers, was computed. Incorporating fully adjusted model, our analysis showed significant correlations PA engagement PhenoAge [Low PA, β (95 % CI): 0.039(-0.071,-0.008), p = 0.021; Moderate 0.058(-0.082,-0.034), < 0.001; High 0.069(-0.096,-0.042), 0.001]. Furthermore, positive link emerged elevated with CI) 0.011(0.001, 0.022), 0.034. A mediation performed, demonstrating that length mediated connection proportion calculated at 3.57 %. Our findings suggest may play key role mitigating processes by preserving highlighting potential as target for interventions aimed promoting healthy longevity.

Language: Английский

Prevalence and determinants of depression and anxiety among Sudanese during the ongoing civil conflicts: A cross-sectional study DOI Creative Commons
Ramy Mohamed Ghazy, Yasmine Yousry Mohammed,

Basma Tolba

et al.

Medicine, Journal Year: 2025, Volume and Issue: 104(11), P. e41553 - e41553

Published: March 14, 2025

Armed conflicts have profound effects on mental health, including elevated rates of depression and anxiety among affected populations. The ongoing civil conflict in Sudan since April 2023 has exacerbated these challenges. This study aimed to determine the prevalence identify determinants Sudanese residents by conflict. cross-sectional was conducted between 1st May 30, 2024. Data were collected through online surveys face-to-face interviews. validated Arabic versions Beck Depression Inventory Hamilton Anxiety Rating Scale used assess levels, respectively. In total, 920 participants included with a mean age 35.0 ± 12.2 years; 52.3% females 90.1% had migrated due conflicts. Of participants, 99.3% 98.6% reported varying levels anxiety, Predictors female sex (β = 4.71, P < .0001), living Eastern state 4.13, rural area 2.33, .012), noncompletion formal education 7.36, .026), working individuals −5.58, larger household sizes (16–20 members) 6.79, sufficient income −10.22, those ability save money −11.56, insufficient −5.61, .0001). predictors being 6.05, 7.11, .024), current −5.56, 6.12, .035), ((β −5.60, −5.52, .004), −2.60, .006). These findings underscore impact war health. Effective humanitarian interventions targeting vulnerable groups addressing socioeconomic are critical for mitigating psychological toll Sudan.

Language: Английский

Citations

0

Association between RAR and the prevalence and prognosis of depression: A population-based study DOI
Xiaofeng Zhu, Yuqi Hu, Zhiwei Long

et al.

Journal of Affective Disorders, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

0

The impact of atmospheric pollutants on the physical health of college students——based on physical examination data of college students from a certain university in Xi’an, Shaanxi Province, China DOI Creative Commons
Jiaxin He, Ke Liu, Zhiyu He

et al.

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: March 24, 2025

Background Air pollution, particularly particulate matter (PM 2.5 /PM 10 ), poses a significant environmental health threat in urban China. While previous research has primarily focused on older adult populations, the impact of air pollution college students—an important yet underexplored demographic—remains largely unclear. This study investigates effects pollutants physical fitness and lung function among students at university Xi’an, city known for its persistent quality challenges. Methods We used longitudinal examination data (2019–2022) from 21,580 to perform empirical correlation regression kernel density estimation. Trends vital capacity scores were analyzed alongside indicators (AQI, PM , CO). A mixed cross-sectional econometric model controlled individual characteristics such as height (mean = 170.66 cm, SD 8.37), weight 64.94 kg, 13.40), gender 0.313, 0.464), factors temperature, wind speed, green coverage 41.22, 1.45). Physical exhibited high variability (SD 9.62, range 10.2–109). Results was significantly associated with reduction scores. 1-unit increase AQI linked 0.1094-unit decline ( p &lt; 0.01). The negative effect further amplified by β −0.2643) CO (β −11.5438). Senior students, especially females, showed increased vulnerability adverse pollution. mirrored those fitness, outliers suggesting susceptibility. Notably, reduced found mediate 22% 0.05). Conclusion highlights disproportionate emphasizing need policies that focus reducing emissions, expanding campus greenery, promoting education. Future should incorporate fixed broaden include wider regions universities.

Language: Английский

Citations

0

Predictive Value of Dietary Inflammatory Index for Recurrence of Plaque Psoriasis—A Retrospective Study DOI Creative Commons
Zheng Gu, Xiaoyan Zhang

British Journal of Hospital Medicine, Journal Year: 2025, Volume and Issue: 86(3), P. 1 - 12

Published: March 26, 2025

Aims/Background Determining the predictive value of dietary inflammatory index on recurrence plaque psoriasis vulgaris is an emerging research area. This study aims to investigate (DII) for psoriasis. Methods A retrospective was conducted 200 patients with who were treated at China-Japan Friendship Hospital from October 2022 December 2023. Patients divided into group (n = 95) and non-recurrence 105) based whether they had experienced a during follow-up. Univariate multivariate logistic regression analyses performed determine influencing factors recurrence. The receiver operating characteristic (ROC) curve used evaluate DII Results Comparisons age, gender, Drinking, duration illness, family history, season onset, history skin allergies showed no statistically significant differences between (p > 0.05). However, comparisons sleep inadequacy, anxiety, smoking, infections, < results analysis indicated that independent ROC predicted area under in predicting 0.815, standard error 0.031 (95% confidence interval (CI): 0.754–0.877, p 0.001) Youden’s 0.60, sensitivity 74.7%, specificity 84.8%. has highest value. Conclusion Characterized by high analysis, exhibits

Language: Английский

Citations

0

Mediation Role of Telomere Length in the Relationship between Physical Activity and PhenoAge: A Population-based Study DOI Creative Commons
Yanwei You,

Dizhi Wang,

Hao Ding

et al.

Journal of Exercise Science & Fitness, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

The relationship between physical activity (PA), telomere length, and phenotypic age (PhenoAge) represents a pivotal area of investigation in aging research. study encompassed cohort 6200 participants aged 20 years above, sourced from the National Health Nutrition Examination Survey (NHANES). Physical (PA) levels were assessed employing Global Activity Questionnaire, while DNA samples collected to determine measured base pairs. PhenoAge, an emerging index relying on nine distinct chemical biomarkers, was computed. Incorporating fully adjusted model, our analysis showed significant correlations PA engagement PhenoAge [Low PA, β (95 % CI): 0.039(-0.071,-0.008), p = 0.021; Moderate 0.058(-0.082,-0.034), < 0.001; High 0.069(-0.096,-0.042), 0.001]. Furthermore, positive link emerged elevated with CI) 0.011(0.001, 0.022), 0.034. A mediation performed, demonstrating that length mediated connection proportion calculated at 3.57 %. Our findings suggest may play key role mitigating processes by preserving highlighting potential as target for interventions aimed promoting healthy longevity.

Language: Английский

Citations

0