Aktualności Neurologiczne, Journal Year: 2024, Volume and Issue: 24(3), P. 114 - 121

Published: Dec. 31, 2024

Introduction and objective: The link between gut microbiota multiple sclerosis has gained significant research interest in recent years. Multiple sclerosis, an autoimmune disease characterised by chronic inflammation demyelination the central nervous system, remains a complex condition with multifactorial aetiology. Recent evidence suggests that alterations composition, known as dysbiosis, may influence pathogenesis progression. This paper aims to review current state of knowledge regarding gut–brain connection exploring how affect mechanisms potential therapeutic approaches. Summary knowledge: axis plays crucial role maintaining homeostasis. In dysbiosis been observed, specific microbial profiles differing patients healthy controls. Gut can modulate immune responses, potentially influencing progression through pathways involving cytokine production T-cell differentiation. Therapeutic interventions such dietary modifications, probiotics, faecal transplantation have shown promise preliminary studies, indicating their improve patient outcomes. Summary: Understanding offers promising possibilities for new strategies. Interventions targeting microbiota, changes, transplantation, show modifying enhancing treatment However, methodologies assessing limitations, requiring improved techniques accurate analysis. Continued investigation into could lead more effective targeted treatments, ultimately improving quality life patients.

Language: Английский