Omega-3 Fatty Acid Supplementation on Post-Exercise Inflammation, Muscle Damage, Oxidative Response, and Sports Performance in Physically Healthy Adults—A Systematic Review of Randomized Controlled Trials

Nutrients, Journal Year: 2024, Volume and Issue: 16(13), P. 2044 - 2044

Published: June 27, 2024

Omega-3 is a family of n-3 polyunsaturated fatty acids (PUFAs), which have been used to treat wide variety chronic diseases, due mainly their antioxidant and anti-inflammatory properties, among others. In this context, omega-3 could be post-exercise recovery agent sports supplement that improve performance by preserving promoting skeletal muscle mass strength. No conclusive evidence, however, exists about the potential effects on biomarkers in physically healthy adults. Based PRISMA Exercise, Rehabilitation, Sports Medicine, Science (PERSiST) guidelines, we systematically reviewed studies indexed Web Science, Scopus, Medline assess inflammation, damage, oxidant response, The search was performed original articles published last 10 years up 5 May 2024, with controlled trial design supplementation compared control group. Among 14,971 records identified search, 13 met selection criteria. duration interventions ranged from 1 day 26 weeks doses were heterogeneous. Creatine kinase (CK) lactate dehydrogenase (LDH) significantly higher (

Language: Английский

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Melatonin decreases PAX7 and CK increment after exercise-induced skeletal muscle damage

Sport Sciences for Health, Journal Year: 2025, Volume and Issue: unknown

Published: March 12, 2025

Language: Английский

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Sports Nutrition: Current and Novel Insights

Nutrients, Journal Year: 2025, Volume and Issue: 17(9), P. 1420 - 1420

Published: April 23, 2025

This Special Issue invited the submission of sports nutrition-based manuscripts that advanced scientific understanding and provided novel insights on all aspects performance recovery [...]

Language: Английский

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Time-of-Day-Dependent Effects of Rehabilitation on Motor Recovery After Experimental Focal Cerebral Ischemia

Stroke, Journal Year: 2025, Volume and Issue: unknown

Published: April 25, 2025

BACKGROUND: Rehabilitation is an efficacious method to improve poststroke motor dysfunction. Various rehabilitative techniques have become popular in this field of research. However, it has not been reported whether better outcomes can be achieved if rehabilitation training conducted at the optimal time day. METHODS: A model photothrombotic ischemic stroke was used C57/BL6 mice, and 24-hour activity cycles were evaluated. We found peak around Zeitgeber (ZT)13 (21:00) a trough ZT20 (04:00) during dark phase. In addition, we selected ZT6 (14:00) as daytime group (corresponding ZT13 group, respectively). The 3 groups underwent treadmill for 4 weeks. Functional histological recovery levels compared among groups. bulk RNA sequencing analysis explore possible molecular mechanisms. RESULTS: results showed that stroke-induced mice maintained regular nocturnal locomotor rhythm with reduced amplitude. Motor greater than trend toward ZT20. also superior neuronal survival neurogenesis ZT6, while improvements between less pronounced. Bulk suggested synaptic plasticity, calcium signaling, cAMP MAPK signaling pathways contributed neural repair differences ZT6. similar pattern female aged trained reinforcing benefits time-of-day training. CONCLUSIONS: conclusion, most active phase beneficial enhanced outcomes. Our study suggests should when body physiological state—that is, time-of-day-dependent strategy.

Language: Английский

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Harnessing the benefits of physical exercise-induced melatonin: a potential promising approach to combat Alzheimer’s disease by targeting beta-amyloid (Aβ)

HORMONES, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 23, 2024

Language: Английский

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Dietary supplement use and knowledge among athletes: prevalence, compliance with AIS classification, and awareness of certification programs

Journal of the International Society of Sports Nutrition, Journal Year: 2025, Volume and Issue: 22(1)

Published: April 22, 2025

The use of dietary supplements is widespread among athletes, with intake influenced by factors such as sport-discipline, competitive level, and gender. Australian Institute Sport (AIS) has categorized based on scientific evidence regarding their efficacy safety. Despite extensive global research supplement data Polish athletes remain limited. Therefore, this study aimed to evaluate considering level Additionally, it assessed whether select in accordance the AIS classification examined awareness certification programs. This cross-sectional included 659 (309 women, 350 men) from various sports, representing both professional (57.7%) nonprofessional (42.3%) levels. An online questionnaire was used assess consumption, sources information supplementation, knowledge anti-doping Supplement according (Groups A - D). Statistical analyses, including chi-square tests Mann Whitney U tests, were conducted differences between well male female participants. high prevalence (91.1%) observed no significant (95.8%) (94.3%) or men (92.0%) women (90.0%). most frequently consumed sports drinks (63.9%), electrolyte (51.6%), isolated protein (54.6%), vitamin D (71.6%), C (59.8%), significantly higher athletes. Male more likely than females consume caffeine (p < 0.001), creatine β-alanine 0.001). Melatonin professionals 0.05). Awareness WADA regulations moderate (72.7%), but programs low, only 18.2% familiar Informed Sport, 10.7% Cologne List. Social media common source (41.9%), while 17.6% consulted qualified specialists nutrition supplementation area. highlights irrespective While many Group A, remains reliance social for information, combined lack guidance, underscores need improved education safe effective practices. Given risks associated contamination, targeted initiatives should enhance athletes' certified options.

Language: Английский

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Melatonin supplementation: new insights into health and disease

Sleep And Breathing, Journal Year: 2025, Volume and Issue: 29(2)

Published: April 25, 2025

Language: Английский

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Nutritional Assessment, Body Composition, and Low Energy Availability in Sport Climbing Athletes of Different Genders and Categories: A Cross-Sectional Study

Nutrients, Journal Year: 2024, Volume and Issue: 16(17), P. 2974 - 2974

Published: Sept. 3, 2024

Climbing is an Olympic discipline in full development and multidisciplinary nature, where the influences of body composition nutritional status on performance have not yet been clarified despite quest for a low weight anti-gravity disciplines such as climbing. The present cross-sectional study aimed to conduct (3-day dietary diaries) (ISAK profile) assessments sport climbing athletes by gender level during months February March 2024. t-test independent samples Mann–Whitney U-test, well ANOVA Kruskal–Wallis H-test, were used compare distributions two or more groups, respectively, Pearson’s Spearman’s correlation coefficients estimate correlations between different variables. mean age 46 Spanish climbers (22 men 24 women) was 30 years (SD: 9) with 7.66 experience 6.63). somatotype classified balanced mesomorph. Negative observed fat mass variables (p < 0.010), positive forearm circumference 0.050). energy availability (EA) 33.01 kcal-kg FFM−1d−1 9.02), 55.6% having suboptimal EA 35.6% (LEA). carbohydrate protein intakes below recommendations 57.8% 31.1% athletes, respectively. There deficient all micronutrients except phosphorus males. These findings suggest that are at high risk developing states concomitant problems. Optimal monitoring may be advisable this type athlete try reduce LEA.

Language: Английский

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Indole-3-Butyric Acid, a Natural Auxin, Protects against Fenton Reaction-Induced Oxidative Damage in Porcine Thyroid

Nutrients, Journal Year: 2024, Volume and Issue: 16(17), P. 3010 - 3010

Published: Sept. 6, 2024

We present results on the potential protective antioxidant properties of indole-3-butyric acid. Indole-3-butyric acid is an indole derivative defined as auxin and widely known a plant growth regulator. It naturally occurs in Arabidopsis thaliana, which applied model genetic studies. Oxidative damage to membrane lipids (lipid peroxidation; LPO) porcine thyroid homogenates was induced by Fenton reaction substrates (Fe2+ + H2O2). Iron (Fe2+) used very high concentrations 1200, 600, 300, 150, 75, 37.5, 18.75, 9.375, 4.687, 2.343 µM. (10.0, 5.0, 2.5, 1.25, 0.625 mM) check whether it prevents above process. The LPO level, expressed malondialdehyde 4-hydroxyalkenals (MDA 4-HDA) concentration, measured spectrophotometrically. Expectedly, substrates, Fe2+ concentration-dependent manner, increased with lowest effective concentration iron being 9.375 In case almost all acid, this has exhibited promising protection, most 10.0 5.0 mM; however, low at 1.25 mM still effective. alone did not change basal level LPO, favourable effect. To summarise, against experimentally oxidative thyroid, for first time documented literature. This compound can be considered natural agent plants, serve dietary nutrient.

Language: Английский

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Effects of Melatonin Administration on Physical Performance and Biochemical Responses Following Exhaustive Treadmill Exercise

Current Issues in Molecular Biology, Journal Year: 2024, Volume and Issue: 46(12), P. 13647 - 13661

Published: Nov. 30, 2024

Exercise, despite being a beneficial activity for health, can also be source of oxidative imbalance, which lead to decrease in performance. Furthermore, melatonin is an endogenous molecule that may counteract exercise-induced stress. The aim this study was evaluate the potential ergogenic and antioxidant capacity administered maximal effort test. A total 30 rats were divided into three groups—control, exercise, exercise + (intraperitoneal administration 10 mg/kg)—to assess effects exhaustive incremental protocol two groups (with without melatonin) on treadmill-running performance (final speed reached), lipid protein oxidation markers (malondialdehyde 4-hidroxyalkenals carbonyl content, respectively), cellular mitochondrial membranes’ fluidity skeletal muscle, brain, liver tissues. Our results show effect (31 ± 4 vs. 36 cm/s), due its properties significantly stronger than protective when performing increasing treadmill until exhaustion. Melatonin reverted membrane rigidity brain caused by no muscle or liver), prevented liver. Differences between tissues’ responses need investigated future elucidate other possible mechanisms explain melatonin’s effect.

Language: Английский

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