European Journal of Clinical Nutrition, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 16, 2024
Language: Английский
Nutrients, Journal Year: 2024, Volume and Issue: 16(16), P. 2657 - 2657
Published: Aug. 11, 2024
Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder characterized by abdominal pain, bloating, diarrhea, and constipation. Recent studies have underscored the significant role of gut microbiota in pathogenesis IBS. Physical exercise, as non-pharmacological intervention, has been proposed to alleviate IBS symptoms modulating microbiota. Aerobic such running, swimming, cycling, shown enhance diversity abundance beneficial bacteria, including Lactobacillus Bifidobacterium. These bacteria produce short-chain fatty acids that possess anti-inflammatory properties support barrier integrity. Studies involving patients participating structured aerobic exercise programs reported improvements their microbiota's composition diversity, alongside an alleviation like pain bloating. Additionally, positively influences mental health reducing stress improving mood, which can further relieve via gut-brain axis. Long-term interventions provide sustained benefits, maintaining stability, supporting immune functions, systemic inflammation. However, must be tailored individual needs avoid exacerbating symptoms. Personalized plans starting with low-to-moderate intensity gradually increasing maximize benefits minimize risks. This review examines impact various types intensities physical on patients, highlighting need for explore optimal protocols. Future research should include larger sample sizes, longer follow-up periods, examine synergistic effects other lifestyle modifications. Integrating into comprehensive management symptom control improve patients' quality life.
Language: Английский
Citations
11
The Journal of Physiology, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 24, 2025
Abstract Cognitive and physical stress have significant effects on brain health, particularly through their influence the central executive network (CEN). The CEN, which includes regions such as dorsolateral prefrontal cortex, anterior cingulate cortex inferior parietal lobe, is to managing demands of cognitively challenging motor tasks. Acute can temporarily reduce connectivity within leading impaired cognitive function emotional states. However a rebound in these states often follows, driven by motivational signals mesocortical mesolimbic pathways, help sustain inhibitory control task execution. Chronic exposure challenges leads long‐term improvements CEN functionality. These changes are supported neurochemical, structural systemic adaptations, including mechanisms tissue crosstalk. Myokines, adipokines, anti‐inflammatory cytokines gut‐derived metabolites contribute biochemical environment that enhances neuroplasticity, reduces neuroinflammation supports neurotransmitters serotonin dopamine. processes strengthen connectivity, improve self‐regulation enable individuals adopt health‐optimizing behaviours. Long‐term activity not only but also risk age‐related decline neurodegenerative diseases. This review highlights role progressive exercise practical approach strengthening promoting offering strategy resilience well‐being across lifespan. image
Language: Английский
Citations
1
International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(9), P. 4112 - 4112
Published: April 26, 2025
The gut microbiome plays a vital role in human health, functioning as metabolic organ that influences nutrient absorption and overall well-being. With growing evidence dietary interventions can modulate the improve this review examines whether healthcare systems should prioritize personalized microbiome-targeted therapies, such probiotics, prebiotics, microbiota transplants, over traditional pharmaceutical treatments for chronic diseases like obesity, diabetes, cardiovascular risk, inflammatory conditions. A systematic using Web of Science Scopus databases was conducted, followed by scientometric analysis. Key pathways, fiber fermentation short-chain fatty acid production, were explored, focusing on their impact lipid glucose metabolism. interactions between microbial metabolites immune system also investigated. Dietary interventions, including increased probiotic intake, show potential addressing dysbiosis linked to conditions, type 2 autoimmune diseases. emphasizes need incorporate modulation strategies into clinical practice research, calling multidisciplinary approach integrates nutrition, microbiology, biochemistry better understand microbiome's complex health.
Language: Английский
Citations
0
European Journal of Clinical Nutrition, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 16, 2024
Language: Английский
Citations
0