Keto-Therapy: Unveiling the Potential of Ketogenic Diet in Psychiatric Care - A Scoping Review

Nutrition, Journal Year: 2025, Volume and Issue: unknown, P. 112710 - 112710

Published: Feb. 1, 2025

Language: Английский

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Treatments for weight gain in schizophrenia

Current Opinion in Psychiatry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 13, 2025

Purpose of review Obesity and related metabolic disorders are extremely common in psychiatric patients, particularly those with schizophrenia. Elucidating this link's neurobiology may inform clinicians researchers rational therapeutic approaches necessary to optimize clinical outcomes. Recent findings Current literature highlights the pivotal role inflammation-oxidative stress-insulin resistance loop pathophysiology both neuropsychiatric disorders. The concept ‘diabetophrenia’ is put forward highlight overlapping neurobiological mechanisms underlying dysfunction schizophrenia symptoms. Innovative treatments, including combination xanomeline trospium incretin-based medicines, demonstrate encouraging potential addressing such complex health challenges. Summary nuanced dynamics chronic inflammation symptomatology underscore significance mental factors a cohesive fashion while considering unique psychosocial contexts, dietary preferences, lifestyle choices. A multidisciplinary strategy essential for incorporating counseling, interventions, behavioral therapies, pharmacotherapy into management ensuing enhanced collaboration among healthcare professionals render obsolete prevailing siloed conceptualizations disorders, opening new vistas generating synergistic insights mind-body systems leading improved quality life patients other conditions.

Language: Английский

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Ketogenic diet, adenosine, and dopamine in addiction and psychiatry

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: March 10, 2025

Adhering to the ketogenic diet can reduce or stop seizures, even when other treatments fail, via mechanism(s) distinct from available therapies. These results have led interest in for treating conditions such as Alzheimer’s disease, depression and schizophrenia. Evidence points neuromodulator adenosine a key mechanism underlying therapeutic benefits of diet. Adenosine represents unique direct link among cell energy, neuronal activity, gene expression, receptors form functional heteromers with dopamine receptors. The importance dopaminergic system is established addiction, are challenges modulating directly. A mediator that could antagonize dopamine’s effects would be useful, due its function location. Studies report improves cognition, sociability, perseverative behaviors, might improve depression. Many translational opportunities based on diet/adenosine come fore, including autism spectrum disorder, painful conditions, range hyperdopaminergic disorders.

Language: Английский

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Measuring the effects of ketogenic diet on neuropsychiatric disorder: A scoping review – Letter to the Editor

Progress in Neuro-Psychopharmacology and Biological Psychiatry, Journal Year: 2024, Volume and Issue: unknown, P. 111246 - 111246

Published: Dec. 1, 2024

Language: Английский

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