Malvidin-3-O-glucoside ameliorates the development of vascular endothelial dysfunction in type 2 diabetes mellitus by inhibiting arginase 1 expression DOI
Yuanqi Lv, Di Li, Guangyi Du

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106592 - 106592

Published: April 1, 2025

Language: Английский

Synthetic Biology Strategies for the Production of Natural Colorants and Their Non-Natural Derivatives DOI

Kyoungwon Kim,

Kyubin Shim,

Yingwei Wang

et al.

ACS Synthetic Biology, Journal Year: 2025, Volume and Issue: unknown

Published: March 11, 2025

Colorants are widely used in our daily lives to give colors diverse chemicals and materials, including clothes, food, drugs, cosmetics, paints. Although synthetic colorants derived from fossil fuels have been predominantly due their low cost, there is a growing need replace them with natural alternatives. This shift driven by increasing concerns over the climate crisis caused excessive fuel use, as well health issues associated consumption of foods, beverages, cosmetics containing petroleum-derived chemicals. In addition, many show health-promoting properties such antioxidant antimicrobial activities. Despite advantages, could not be readily commercialized distributed market stability, limited color spectrum, yields resources. To this end, biology approaches developed efficiently produce renewable resources high yields. Strategies diversify non-natural derivatives enhanced an expanded spectrum also developed. Review, we discuss recent strategies for enhancing production derivatives, together accompanying examples. Challenges ahead future perspectives discussed.

Language: Английский

Citations

0

Diabetes Therapeutics of Prebiotic Soluble Dietary Fibre and Antioxidant Anthocyanin Supplement in Patients with Type 2 Diabetes: Randomised Placebo-Controlled Clinical Trial DOI Open Access

Chompoonut Teparak,

Juntanee Uriyapongson,

Jatuporn Phoemsapthawee

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(7), P. 1098 - 1098

Published: March 21, 2025

Antioxidants and prebiotics are popular functional foods known for their distinct physiological ameliorating benefits on type 2 diabetes mellitus (T2DM). Whether how a combined antioxidant-prebiotic supplement affects primary secondary T2DM outcomes is not known. We investigated the therapeutic effects of an antioxidant (anthocyanin from riceberry rice) with (dietary fibre rice bran Jerusalem artichoke) glucose control, lipid profile, oxidative stress, inflammation, cardiorespiratory fitness in patients. A total 60 patients were randomly assigned to receive antioxidant/prebiotic (supplement group, SG) or maltodextrin (control CG), (two capsules (350 mg)/meal after three meals before bedtime, 2.8 g/day), days. Venous blood samples collected at baseline days intervention assess metabolic variables (glucose, insulin, profiles, renal liver functions, inflammation). Nutrition status, anthropometry, body composition (DEXA) also measured. Analysis co-variance showed superior T2DM's profiles SG compared CG including reduced fasting (p = 0.01 within-group effects, p 0.03 interaction effects), glycated haemoglobin 0.004 0.002 interaction), low density lipoprotein 0.006 0.02 effects). No significant change was found within any these parameters. Kidney function's glomerular filtration rate improved but placebo CG. Intermediatory biomarkers significantly affected either group no effects. adverse detected following 60-day supplementation intervention. The findings suggest that anthocyanin-fibre may be promoted as adjacent therapy T2DM, intermediary mechanisms action require further research.

Language: Английский

Citations

0

Nutritional composition and organoleptic quality of instant local black rice (cempo ireng) with moderate glycemic index DOI Creative Commons

Aprinia Dian Nurhayati,

Arindra Nirbaya,

Cassandra Permata Nusa

et al.

BIO Web of Conferences, Journal Year: 2025, Volume and Issue: 153, P. 03016 - 03016

Published: Jan. 1, 2025

This research aims to develop instant rice from local black variety, Cempo Ireng, that is safe for diabetes mellitus. Instant was made through the process of soaking in sodium citrate, washing, cooking using a cooker, freezing freezer 24 hours, thawing at room temperature, and drying dehydrator. There were 3 formula including (1) 5% citrate (2) 50 0 C, (3) 7% C. All formulated then tested its nutritional content (including anthocyanin, dietary fiber, amylose, amylopectin, starch, water content, ash, protein, fat, carbohydrates). The also hedonic quality by 35 semi-trained panelists. 50°C has highest score color. temperature have same aroma. third best based on panelists' choices anthocyanin content. It glycemic index. results showed moderate index 60.

Language: Английский

Citations

0

Malvidin-3-O-Glucoside Ameliorates the Development of Vascular Endothelial Dysfunction in Type 2 Diabetes Mellitus by Inhibiting Arginase 1 Expression DOI
Yuanqi Lv, Di Li, Guangyi Du

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0

Malvidin-3-O-glucoside ameliorates the development of vascular endothelial dysfunction in type 2 diabetes mellitus by inhibiting arginase 1 expression DOI
Yuanqi Lv, Di Li, Guangyi Du

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106592 - 106592

Published: April 1, 2025

Language: Английский

Citations

0