The anticarcinogenic properties of manuka honey - a literature review DOI Creative Commons

Adrianna Muciek,

Martyna Mocarska,

Anna Orłowska

et al.

Quality in Sport, Journal Year: 2024, Volume and Issue: 25, P. 56542 - 56542

Published: Dec. 27, 2024

Background: Since antiquity, honey has been recognised for its healing and antibacterial properties. Recently, Manuka (MH) identified as possessing antioxidant, anti-inflammatory, antimutagenic, anticarcinogenic effects. Objective: This review examines the potential benefits of manuka honey, bioactive components, their effects on cancerogenesis, cancer growth, development. Methods: The PubMed Google Scholar databases were searched, 46 studies most relevant to research objective. Results: accompanying papers posit that MH may impede carcinogenesis by regulating various molecular pathways cell progression. A substantial body scientific evidence indicates a range types, including MH, can facilitate release reactive oxygen species cytokines (predominantly IL-1β, IL-6, TNF-α) innate immune system cells. Furthermore, have demonstrated stimulate T lymphocytes macrophages' proliferation functions while also inducing apoptosis cycle arrest in Conclusion: attesting properties continues grow. Several significant role promoting adaptive immunity, which is essential eliminating Nevertheless, further required provide comprehensive data regarding active constituents efficacy therapy.

Language: Английский

Understanding the Anticancer Properties of Honey DOI Open Access
Simona Martinotti, Gregorio Bonsignore, Elia Ranzato

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(21), P. 11724 - 11724

Published: Oct. 31, 2024

Uncontrolled cell growth that possesses the capacity to exhibit malignant behavior is referred as cancer. The cytotoxic drugs used fight cancer are associated with several adverse effects and not always readily available or affordable, especially in developing countries. These issues addition shortcomings of current treatment regimen. According growing research, honey normal cells but highly particularly tumor cells, suggesting may display anticancer effects. Research has shown affects a number signaling pathways; however, at moment, precise method completely known.

Language: Английский

Citations

5
Trends, key contributors, and emerging issues in honey and breast cancer: A bibliometric analysis from 2014 to 2024 DOI Creative Commons
Andi Nilawati Usman, Fendi Fendi, Zafitri Nulandari

et al.

F1000Research, Journal Year: 2025, Volume and Issue: 14, P. 17 - 17

Published: Jan. 3, 2025

Background Honey, a natural product with diverse bioactive compounds, has been increasingly explored for its potential anticancer properties. This study aims to comprehensively analyze the scientific literature on relationship between honey and breast cancer. Methods A bibliometric analysis was conducted using ScienceDirect database identify publications from 2014 2024. Data publication trends, author collaboration, keyword were extracted gain insight into research landscape. Keyword identified nine distinct clusters, indicating directions regarding role of in cancer treatment. Results Key journals such as Journal Ethnopharmacology Food Chemistry have at forefront disseminating findings this domain, demonstrating strong interdisciplinary approach that bridges traditional medicine modern inquiry. The increasing interest properties honey, evidenced by growing number studies, underlines promising agent prevention Recent advances synthesis theranostic paradigms cerium oxide nanoparticles (CeONPs) highlighted, well selenium nanoconstructs. toxicity quality control Perillae Fructus also highlighted. Conclusions provides comprehensive overview current state knowledge uncovers emerging issues require further investigation.

Language: Английский

Citations

0
Trends, key contributors, and emerging issues in honey and breast cancer: A bibliometric analysis from 2014 to 2024 DOI Creative Commons
Andi Nilawati Usman, Fendi Fendi, Zafitri Nulandari

et al.

F1000Research, Journal Year: 2025, Volume and Issue: 14, P. 17 - 17

Published: Jan. 20, 2025

Background Honey, a natural product with diverse bioactive compounds, has been increasingly explored for its potential anticancer properties. This study aims to comprehensively analyze the scientific literature on relationship between honey and breast cancer. Methods A bibliometric analysis was conducted using ScienceDirect database identify publications from 2014 2024. Data publication trends, author collaboration, keyword were extracted gain insight into research landscape. Keyword identified nine distinct clusters, indicating directions regarding role of in cancer treatment. Results Key journals such as Journal Ethnopharmacology Food Chemistry have at forefront disseminating findings this domain, demonstrating strong interdisciplinary approach that bridges traditional medicine modern inquiry. The increasing interest properties honey, evidenced by growing number studies, underlines promising agent prevention Recent advances synthesis theranostic paradigms cerium oxide nanoparticles (CeONPs) highlighted, well selenium nanoconstructs. toxicity quality control Perillae Fructus also highlighted. Conclusions provides comprehensive overview current state knowledge uncovers emerging issues require further investigation.

Language: Английский

Citations

0
Catharanthus roseus (L.) G. Don: A herb with the potential for curing breast cancer DOI

Selvarajah Saman,

Aqsa Hanif,

Sawsan S. Al-Rawi

et al.

Next research., Journal Year: 2025, Volume and Issue: unknown, P. 100218 - 100218

Published: Feb. 1, 2025

Language: Английский

Citations

0
Trends, key contributors, and emerging issues in honey and breast cancer: A bibliometric analysis from 2014 to 2024 DOI Creative Commons
Andi Nilawati Usman, Fendi Fendi, Zafitri Nulandari

et al.

F1000Research, Journal Year: 2025, Volume and Issue: 14, P. 17 - 17

Published: March 24, 2025

Background Honey, a natural product with diverse bioactive compounds, has been increasingly explored for its potential anticancer properties. This study aims to comprehensively analyze the scientific literature on relationship between honey and breast cancer. Methods A bibliometric analysis was conducted using ScienceDirect database identify publications from 2014 2024. Data publication trends, author collaboration, keyword were extracted gain insight into research landscape. Keyword identified nine distinct clusters, indicating directions regarding role of in cancer treatment. Results In Key journals such as Journal Ethnopharmacology Food Chemistry have at forefront disseminating findings this domain, demonstrating strongly interdisciplinary approach that bridges traditional medicine modern inquiry. The increasing interest properties honey, evidenced by growing number studies, underlines promising agent prevention Conclusions provides comprehensive overview current knowledge landscape highlights emerging issues require further exploration.

Language: Английский

Citations

0
Honey Targets Ribosome Biogenesis Components to Suppress the Growth of Human Pancreatic Cancer Cells DOI Open Access

Aun Ali Bangash,

Sahir Sultan Alvi, Muhammad Bangash

et al.

Cancers, Journal Year: 2024, Volume and Issue: 16(19), P. 3431 - 3431

Published: Oct. 9, 2024

Pancreatic cancer (PanCa) is one of the deadliest cancers, with limited therapeutic response. Various molecular oncogenic events, including dysregulation ribosome biogenesis, are linked to induction, progression, and metastasis PanCa. Thus, discovery new therapies suppressing these events biogenesis could be a novel approach for prevention treatment The current study was designed investigate anti-cancer effect honey against Our results indicated that markedly inhibited growth invasive characteristics pancreatic cells by mRNA expression protein levels key components RNA Pol-I subunits (RPA194 RPA135) along its transcriptional regulators, i.e., UBTF c-Myc. Honey also induced nucleolar stress in PanCa reducing various proteins (NCL, FBL, NPM). Honey-mediated regulation on organization-associated significantly arrested cell cycle G2M phase apoptosis cells. These results, first time, demonstrated honey, being natural remedy, has potential induce inhibit metastatic phenotypes targeting biogenesis.

Language: Английский

Citations

1
The anticarcinogenic properties of manuka honey - a literature review DOI Creative Commons

Adrianna Muciek,

Martyna Mocarska,

Anna Orłowska

et al.

Quality in Sport, Journal Year: 2024, Volume and Issue: 25, P. 56542 - 56542

Published: Dec. 27, 2024

Background: Since antiquity, honey has been recognised for its healing and antibacterial properties. Recently, Manuka (MH) identified as possessing antioxidant, anti-inflammatory, antimutagenic, anticarcinogenic effects. Objective: This review examines the potential benefits of manuka honey, bioactive components, their effects on cancerogenesis, cancer growth, development. Methods: The PubMed Google Scholar databases were searched, 46 studies most relevant to research objective. Results: accompanying papers posit that MH may impede carcinogenesis by regulating various molecular pathways cell progression. A substantial body scientific evidence indicates a range types, including MH, can facilitate release reactive oxygen species cytokines (predominantly IL-1β, IL-6, TNF-α) innate immune system cells. Furthermore, have demonstrated stimulate T lymphocytes macrophages' proliferation functions while also inducing apoptosis cycle arrest in Conclusion: attesting properties continues grow. Several significant role promoting adaptive immunity, which is essential eliminating Nevertheless, further required provide comprehensive data regarding active constituents efficacy therapy.

Language: Английский

Citations

0