Synthetic and Systems Biotechnology, Journal Year: 2024, Volume and Issue: 10(1), P. 307 - 313
Published: Nov. 22, 2024
Language: Английский
Medicine, Journal Year: 2025, Volume and Issue: 104(12), P. e41891 - e41891
Published: March 21, 2025
Febrile seizures (FS) are among the most common neurological disorders in childhood, and their pathogenesis may be influenced by multiple factors. As scientific research progresses, significant role of B vitamins nervous system has become progressively clearer. In this study, children clinically diagnosed with FS were selected as experimental group, febrile without a history convulsions or family control group to investigate potential correlation between whole-blood vitamin levels. The concentrations whole blood measured using liquid chromatography-mass spectrometry, statistical analyses conducted SPSS 25.0, followed significance testing. levels B1, B2, B5, B6, B7, B12 significantly higher than those particularly B5 B7 (P < .05). Additionally, statistically differences observed sodium calcium ion These results suggest that complex outcome factors, including known channel defects. Vitamin play warrants further investigation.
Language: Английский
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Bioorganic Chemistry, Journal Year: 2025, Volume and Issue: 160, P. 108438 - 108438
Published: April 5, 2025
Language: Английский
Citations
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Frontiers in Veterinary Science, Journal Year: 2025, Volume and Issue: 12
Published: April 15, 2025
The objective of this study was to determine the effects biotin on growth performance, serum biochemical profiles, and morphology acetate gossypol-treated mice. Seventy-five healthy male Kunming mice were randomly assigned five treatment groups: control group (C), (BC), gossypol (AGC), prevention (BP) (BT). examined visceral index, profiles histomorphological changes results showed that compared with AGC mice, average daily feed intake BP BT increased by 40.47 45.69% ( p < 0.05). Biotin reduced elevated blood urea nitrogen (BUN) levels in aspartate aminotransferase (AST), total protein (TP) BUN increase values villus height/crypt depth duodenum jejunum In conclusion, potentially performance it also has a positive effect
Language: Английский
Citations
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Frontiers in Cellular and Infection Microbiology, Journal Year: 2025, Volume and Issue: 15
Published: April 17, 2025
The rising use of dental implants is accompanied by an expected increase in peri-implant diseases, particularly peri-implantitis (PI), which poses a significant threat to implant success and necessitates thorough understanding its pathogenesis for effective management. To gain deeper insights into the role impact microbiome progression PI, we analyzed 100 samples saliva subgingival biofilm from 40 participants with healthy (HI group) or co-occurrence diagnosed PI-affected (PI using shotgun metagenomic sequencing. We identified most discriminative species distinguishing diseased study groups through log ratios differential ranking analyses. Mogibacterium timidum, Schaalia cardiffensis, Parvimonas micra, Filifactor alocis, Porphyromonas endodontalis, gingivalis Olsenella uli were associated biofilm. In contrast, Neisseria sp oral taxon 014, Haemophilus parainfluenzae, Actinomyces naeslundii, Rothia mucilaginosa aeria more prevalent Functional pathways such as arginine polyamine biosynthesis, including putrescine citrulline showed stronger correlations implants. health was characterized predominance involved purine pyrimidine deoxyribonucleotide de novo glucose glucose-1-phosphate degradation, tetrapyrrole biosynthesis. Our findings reveal that PI-free cavities differ significantly microbial composition functional compared co-occurring implants, closely resemble PI-associated profiles. This pattern extended salivary samples, where biomarkers follow similar trends.
Language: Английский
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Synthetic and Systems Biotechnology, Journal Year: 2024, Volume and Issue: 10(1), P. 307 - 313
Published: Nov. 22, 2024
Language: Английский
Citations
0