The modified role including mediating and synergistic interactive effects of glucose tolerance status in the associations between relative fat mass and the risks of cardiovascular disease and all-cause mortality from the 4C cohort study DOI Creative Commons
Peiqiong Luo, Danpei Li,

Yaming Guo

et al.

Diabetology & Metabolic Syndrome, Journal Year: 2024, Volume and Issue: 16(1)

Published: Dec. 26, 2024

To investigate the associations between relative fat mass (RFM) and clinical outcomes in different glucose tolerance statuses modified effect of status. We analyzed 8,224 participants from a Chinese cohort study, who were classified into normal status (NGT), prediabetes, diabetes. Outcomes included fatal, nonfatal cardiovascular disease (CVD) events all-cause mortality. Associations RFM assessed using Cox regression. The was investigated mediation, interaction, joint analyses. During up to 5 years follow-up, 154 (1.9%) experienced fatal CVD, 153 CVD events, 294 (3.6%) death. 2,679 (32.6%) had NGT, 4,528 (54.8%) 1,037 (12.6%) associated with increased risk (HR [95% CI], 1.09 [1.06–1.12], p < 0.001), 1.12 [1.09–1.15], mortality 1.10 [1.08–1.12), 0.001) all those diabetes, these by status, which mediating (mediation proportion ranges 4.74% 8.69%) synergistic interactive effects (multiplicative 1.03 1.06). analysis identified subclassification that exhibited highest HR among 12 subclassifications. could significantly influence how clinicians assess high lead more personalized, effective prevention strategies.

Language: Английский

Antioxidant Capacity, Lipid Oxidation, and Quality Traits of Slow- and Fast-Growing Meagre (Argyrosomus regius) Fillets During Cold Storage DOI Creative Commons

Ioannis Mittakos,

Cosmas Nathanailides, Lambros Kokokiris

et al.

Antioxidants, Journal Year: 2025, Volume and Issue: 14(2), P. 124 - 124

Published: Jan. 21, 2025

Meagre (Argyrosomus regius) is an important species in aquaculture, with size and flesh quality playing key roles its production marketability. This study aimed to examine the relationship between growth parameters, including fatty acid content (FA), total antioxidant capacity (TOAC), superoxide dismutase (SOD), lipid oxidation (LO), muscle cellularity (MC), filleting yield (FY) during cold storage. Fish from same hatchery raised under identical conditions showed variation after 12 months. below 600 g were classified as slow growing (SG), while those above 1000 fast-growing (FG). The results that FG fish had higher body weight, moisture, FY but exhibited lower levels of fat polyunsaturated acids (PUFA). SG TOAC SOD activity, which significantly declined storage both groups remained fish. Despite fish, no significant differences malondialdehyde (MDA) levels, indicator LO, observed two groups, suggesting elevated defenses mitigated peroxidation. underscores intrinsic antioxidants’ potential preserve fillets

Language: Английский

Citations

0
Dietary Oleic Acid and SCD16 and ELOVL6 Estimated Activities Can Modify Erythrocyte Membrane n-3 and n-6 HUFA Partition: A Pilot Study DOI Creative Commons
Paulo Bispo, Pedro Rodrigues, Narcisa M. Bandarra

et al.

Current Issues in Molecular Biology, Journal Year: 2025, Volume and Issue: 47(2), P. 81 - 81

Published: Jan. 27, 2025

In this work, we studied the relationships between most representative fatty acids (FAs) and their ratios in red blood cell (RBC) membranes dietary alongside several cardiometabolic risk factors. Twenty-six individuals were enrolled with a mean age of 50.4 ± 12.7 years (16 males 10 females). By bivariate analysis, oleic acid (OA) correlated negatively C20:4n-6 (AA) (p = 0.031) RBCs. With multivariate regression OA < 0.001) is an independent predictor associated AA levels RBCs, while elongation very-long-chain 6 (ELOVL6) stearoyl-CoA desaturase 16 (SCD16) activities 0.05) was positively The models also showed that C22:5n-3 (DPA) Furthermore, BMI SCD16, both SCD16 SCD18 triacylglycerols levels. addition, significantly LDL-c LDL-c/HDL-c ratio ApoA1/ApoB ratio, ELOVL6 HDL molecular subfractions. Therefore, our data underline OA, can interfere n-3 n-6 partition biomembranes such as suggesting important (patho)physiological regulatory mechanism role controlling bioactive molecules’ availability those involved immune-inflammatory response.

Language: Английский

Citations

0
Preparation and characterization of lauric acid-rich wax oleogel chocolates: Insights into crystallization behavior, storage stability, and bloom resistance DOI
Yuting Fu, Yu Chen, Pengyan Li

et al.

Food Research International, Journal Year: 2025, Volume and Issue: 204, P. 115886 - 115886

Published: Jan. 31, 2025

Language: Английский

Citations

0
Lipids in Clinical Nutrition and Health: Narrative Review and Dietary Recommendations DOI Creative Commons
Adrian Frydrych,

Kamil Kulita,

Kamil Jurowski

et al.

Foods, Journal Year: 2025, Volume and Issue: 14(3), P. 473 - 473

Published: Feb. 1, 2025

Lipids are essential components of human health, serving as critical structural elements cell membranes, energy sources, and precursors for bioactive molecules. This narrative review aims to examine the multifaceted roles lipids in clinical nutrition focusing on their impact chronic disease prevention, management, potential lipid-based therapies. A was conducted utilizing Scopus, Google Scholar, Web Science databases. Key terms such lipids, dietary fats, cholesterol were used identify analyze relevant studies. total 145 articles meeting inclusion criteria reviewed insights into lipid metabolism, implications. The analysis highlighted metabolic significance various classes—saturated, monounsaturated, polyunsaturated fatty acids—along with evidence-based recommendations intake. shown play a pivotal role managing diseases cardiovascular disease, obesity, syndrome. Emerging therapies, including omega-3 acids medium-chain triglycerides, demonstrated benefits practice. By synthesizing current knowledge, this provides healthcare professionals an updated understanding nutrition. findings emphasize importance tailored interventions therapies optimizing health effectively. Additionally, successfully presents practical guide

Language: Английский

Citations

0
Modeling and optimization of docosahexaenoic acid production by Schizochytrium sp. based on kinetic modeling and genetic algorithm optimized artificial neural network DOI
Zilei Chen,

Hui Lian,

Linhui Yang

et al.

Bioresource Technology, Journal Year: 2025, Volume and Issue: unknown, P. 132291 - 132291

Published: Feb. 1, 2025

Language: Английский

Citations

0
Seeds of Coix lacryma-jobi as a functional additive for starch-rich bread and their effects on bread quality and starch digestibility DOI Creative Commons
Wing‐Fu Lai,

Weijie Fang,

Tong Fu

et al.

LWT, Journal Year: 2025, Volume and Issue: unknown, P. 117721 - 117721

Published: April 1, 2025

Language: Английский

Citations

0
Comparison of the Nutritional Composition of Meat Products Derived from Croatian Indigenous Pig Breeds DOI Creative Commons
Ana Vulić, Željko Cvetnić, Ivica Kos

et al.

Foods, Journal Year: 2024, Volume and Issue: 13(24), P. 4175 - 4175

Published: Dec. 23, 2024

There is a growing interest in the preservation of indigenous pig breeds, as they serve valuable genetic reserve. Pork meat products are widely consumed due to their desirable flavor, which largely influenced by chemical composition and production processes employed. The aim this study was characterize compare nutritional composition, mineral content, fatty acid profile derived from Croatian breeds. Three types products, including bacon, dry-cured ham, dry-fermented sausages, originating Turopolje pig, Black Slavonian Banijska šara, were collected analyzed for proximate profile, content. Concerning analysis, statistically significant differences found water fat content bacon while analysis revealed iron tested be accordance with previously reported data. results indicated similarities between different breeds; however, performing PCA that major influence on product breed characterization could attributed composition.

Language: Английский

Citations

1
Recent developments, challenges, and prospects of dietary omega-3 PUFA-fortified foods: Focusing on their effects on cardiovascular diseases DOI
Yongjin Wang, Gangcheng Wu, Yandan Wang

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 470, P. 142498 - 142498

Published: Dec. 19, 2024

Language: Английский

Citations

0
The modified role including mediating and synergistic interactive effects of glucose tolerance status in the associations between relative fat mass and the risks of cardiovascular disease and all-cause mortality from the 4C cohort study DOI Creative Commons
Peiqiong Luo, Danpei Li,

Yaming Guo

et al.

Diabetology & Metabolic Syndrome, Journal Year: 2024, Volume and Issue: 16(1)

Published: Dec. 26, 2024

To investigate the associations between relative fat mass (RFM) and clinical outcomes in different glucose tolerance statuses modified effect of status. We analyzed 8,224 participants from a Chinese cohort study, who were classified into normal status (NGT), prediabetes, diabetes. Outcomes included fatal, nonfatal cardiovascular disease (CVD) events all-cause mortality. Associations RFM assessed using Cox regression. The was investigated mediation, interaction, joint analyses. During up to 5 years follow-up, 154 (1.9%) experienced fatal CVD, 153 CVD events, 294 (3.6%) death. 2,679 (32.6%) had NGT, 4,528 (54.8%) 1,037 (12.6%) associated with increased risk (HR [95% CI], 1.09 [1.06–1.12], p < 0.001), 1.12 [1.09–1.15], mortality 1.10 [1.08–1.12), 0.001) all those diabetes, these by status, which mediating (mediation proportion ranges 4.74% 8.69%) synergistic interactive effects (multiplicative 1.03 1.06). analysis identified subclassification that exhibited highest HR among 12 subclassifications. could significantly influence how clinicians assess high lead more personalized, effective prevention strategies.

Language: Английский

Citations

0