Associations between dietary coenzyme Q10 intake and lipid profiles in adults: a national cross-sectional study DOI Creative Commons

Mingzhu Zhao,

Zezhong Tian, Dan Zhao

et al.

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: Nov. 12, 2024

Objective This study aimed to determine the average intake of CoQ10 from dietary sources and explore dose–response relationships between dietary-derived lipid profiles. Methods We performed a cross-sectional based on China Health Nutrition Survey, which included 7,938 adults. The assessment used three consecutive 24-h recalls combined with household inventory. Serum was for profiling. Results 5.4 mg/day in Chinese highest quartile (Q4 ≥ 6.96 mg/day) negatively associated total cholesterol (TC) [−0.12 (−0.19, −0.06) mmol/L], low-density lipoprotein (LDL-C) [−0.17 (−0.23, −0.10) non-high-density (non-HDL-C) (−0.18, −0.05) while positively apolipoprotein A-1 (ApoA1) [0.10 (0.08, 0.13) g/L] triglycerides (TG) [0.14 (0.05, 0.23) compared lowest (Q1 < 1.88 mg/day). Besides, showed nonlinear associations above variables (all P 0.05). Conclusion Dietary-derived may be some profiles, such as TG, ApoA1, TC, LDL-C, non-HDL-C. However, not good choice individuals who need supplement.

Language: Английский

Association between dietary coenzyme Q10 intake and hyperuricemia in Chinese adults: a nationwide cross-sectional study DOI Creative Commons

Huiying Kuang,

Dan Zhao, Zezhong Tian

et al.

BMC Public Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 27, 2025

Language: Английский

Citations

0
Effectiveness of Coenzyme Q10 in Uncontrolled Diabetes Mellitus: A Double-blinded Randomized Controlled Trial DOI Open Access
M. R. Suchitra, Srinivasan Parthasarathy

SBV Journal of Basic Clinical and Applied Health Science, Journal Year: 2025, Volume and Issue: 8(1), P. 3 - 6

Published: Jan. 1, 2025

Introduction: Diabetes mellitus is one of the metabolic disorders body, marked with persistent hyperglycemia, which leads to acute complications. Coenzyme Q10 (CoQ10) a liposoluble antioxidant that might benefit in lowering blood glucose and decreasing oxidative stress diabetic patients. This research investigates role CoQ10 supplementation affecting HbA1c values patients uncontrolled type 2 diabetes mellitus. Methodology: It was randomized, double-blind, placebo-controlled trial on 60 eligible diagnosed These were randomized either Group Q 100 mg per day or C placebo for 3 months. Baseline data age, body mass index (BMI), preintervention level noted. The study outcome measure interest change postintervention levels Student’s t -test applied analyze. Results: Compliance similar both groups, no dropout reported. demographic characteristics similar, mean ages 52.66 ± 10.06 years 53.4 8.9 ( P = 0.123). Preprocedural 8.76 0.32% 8.67 0.23% 0.44). Postintervention reduced 8.59 0.78% 8.47 0.67% 0.08 0.09, respectively. No patient experienced serious side effects, changes noted weight participants groups. Conclusions: did not significantly improve after months Although has potential as an adjunct therapy, its efficacy glycemic control remains questionable. Unless proven benefits are there, very prudent keep higher HbA1C more time. Further investigations larger samples diverse populations required explore management.

Language: Английский

Citations

0
Trends in Coenzyme Q10 Supplement Use and Associations With All‐Cause and Cardiovascular Mortality: A Population‐Based Cohort Study DOI Open Access

Lihan Liang,

Zepei Zhong,

Zezhong Tian

et al.

Molecular Nutrition & Food Research, Journal Year: 2025, Volume and Issue: unknown

Published: March 21, 2025

Coenzyme Q10 (CoQ10) is a fat-soluble nutrient, which has antioxidant and anti-inflammatory properties. However, there insufficient evidence on its daily use the association with mortality. We aimed to evaluate trends of CoQ10 supplement among US noninstitutionalized adults explore associations all-cause CVD A prospective cohort study used data from National Health Nutrition Examination Survey (1999-2018). The supplementation mortality was assessed Cox proportional hazard models. overall reported prevalence increased 1.2% (95% CI 0.7%-1.8%) in 1999-2000 4.6% 3.4%-6.1%) 2017-2018 (linear p = 0.002). During an average 9.8 years follow-up, 5237 deaths were identified, including 1428 due CVD. In multivariable model, not associated (HR 1.00, 95% 0.77-1.30, 0.996) 1.30, 0.89-1.90, 0.170). Subgroup analyses suggested that supplements higher obese participants 1.45, 1.01-2.08, for interaction 0.013). Although experienced continuous growth 1999 2018 general NHANES,

Language: Английский

Citations

0
Associations between dietary coenzyme Q10 intake and lipid profiles in adults: a national cross-sectional study DOI Creative Commons

Mingzhu Zhao,

Zezhong Tian, Dan Zhao

et al.

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: Nov. 12, 2024

Objective This study aimed to determine the average intake of CoQ10 from dietary sources and explore dose–response relationships between dietary-derived lipid profiles. Methods We performed a cross-sectional based on China Health Nutrition Survey, which included 7,938 adults. The assessment used three consecutive 24-h recalls combined with household inventory. Serum was for profiling. Results 5.4 mg/day in Chinese highest quartile (Q4 ≥ 6.96 mg/day) negatively associated total cholesterol (TC) [−0.12 (−0.19, −0.06) mmol/L], low-density lipoprotein (LDL-C) [−0.17 (−0.23, −0.10) non-high-density (non-HDL-C) (−0.18, −0.05) while positively apolipoprotein A-1 (ApoA1) [0.10 (0.08, 0.13) g/L] triglycerides (TG) [0.14 (0.05, 0.23) compared lowest (Q1 < 1.88 mg/day). Besides, showed nonlinear associations above variables (all P 0.05). Conclusion Dietary-derived may be some profiles, such as TG, ApoA1, TC, LDL-C, non-HDL-C. However, not good choice individuals who need supplement.

Language: Английский

Citations

1