Intermittent fasting for glycemic control in patients with type 2 diabetes: a meta-analysis of randomized controlled trials
Xiaoyi Huang,
No information about this author
Gan Huang,
No information about this author
Guo Wei
No information about this author
et al.
Nutrición Hospitalaria,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
to
systematically
evaluate
the
efficacy
and
safety
of
Intermittent
Fasting
(IF)
in
patients
with
type
2
diabetes
(T2DM).
randomized
controlled
trials
(RCTs)
on
IF
intervention
T2DM
were
searched
from
PubMed,
The
Cochrane
Library,
Web
Science,
MEDLINE
CNKI,
retrieval
time
was
set
database
onset
September
2024.
A
meta-analysis
performed
using
RevMan
5.3
software.
sixteen
articles
included,
a
total
5369
patients.
showed
that,
compared
control
group,
could
improve
patients'
glycated
hemoglobin,
fasting
plasma
glucose,
body
weight,
BMI,
waist
circumference,
systolic
blood
pressure,
diastolic
low
density
lipoprotein,
cholesterol
levels
(p
<
0.05).
However,
there
no
significant
difference
improving
postprandial
high-density
triglyceride
group
>
may
help
people
manage
their
sugar
effectively.
In
addition,
can
reduce
maintain
stable
low-density
lipoprotein
levels,
is
considered
safe
feasible
implement.
more
high-quality
studies
are
needed
provide
further
evidence
benefits
other
lipid
levels.
Language: Английский
The effectiveness of fasting regimens on serum levels of some major weight regulating hormones: a GRADE-assessed systematic review and meta-analysis in randomized controlled trial
Journal of Health Population and Nutrition,
Journal Year:
2025,
Volume and Issue:
44(1)
Published: April 2, 2025
Language: Английский
The 5:2 Diet Affects Markers of Insulin Secretion and Sensitivity in Subjects with and without Type 2 Diabetes—A Non-Randomized Controlled Trial
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(17), P. 9731 - 9731
Published: Sept. 8, 2024
This
non-randomized
controlled
trial
aimed
to
compare
the
effect
of
5:2
diet
on
insulin
levels
as
a
primary
outcome
and
markers
secretion
(connecting
peptide
(C-peptide)
insulin-like
growth
factor
binding
protein-1
(IGFBP-1))
sensitivity
(Homeostatic
Model
Assessment
for
Insulin
Resistance
(HOMA-IR)),
well
body
composition
secondary
outcomes
in
overweight/obese
individuals
with
without
type
2
diabetes
(T2D).
Ninety-seven
participants
(62%
women),
35
T2D
62
BMI-
waist-matched
controls
T2D,
followed
(two
days
per
week
fasting)
six
months
12-month
follow-up.
At
months,
there
was
no
loss
follow-up
group,
whereas
four
discontinued
this
study.
Overall,
82%
attended
After
intervention,
decreased
control
group
glucose
while
C-peptide,
HOMA-IR,
waist
circumference,
BMI,
trunk,
total
fat%
both
groups.
Furthermore,
low
IGFBP-1,
indicating
hyperinsulinemia,
improved
group.
The
changes
fasting
measurement
were
significantly
more
than
controls.
Persistent
positive
effects
observed
at
feasible
efficient
reduce
resistance
therefore
holds
promise
management
overweight/obesity
subjects
T2D.
Language: Английский
LITERATURE REVIEW : PENGARUH INTERMITTENT FASTING TERHADAP PENURUNAN KADAR HBA1C PENDERITA DIABETES DI ASIA
Yopa Frisdiana,
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Trisari Anggondowati
No information about this author
PREPOTIF Jurnal Kesehatan Masyarakat,
Journal Year:
2024,
Volume and Issue:
8(3), P. 7552 - 7563
Published: Dec. 29, 2024
Diabetes
merupakan
penyakit
kronis
yang
dapat
menyebabkan
komplikasi
serius
dan
meningkatkan
risiko
kematian.
Menurut
International
Federation,
60%
populasi
diabetes
global
tinggal
di
wilayah
Asia.
Salah
satu
indikator
penting
dalam
pengelolaan
adalah
kadar
hemoglobin
A1c
(HbA1c),
menggambarkan
pengendalian
glukosa
darah.
Intermittent
fasting
(IF)
telah
dipertimbangkan
sebagai
metode
non-farmakologis
untuk
mengontrol
darah,
namun
efeknya
pada
penderita
Asia
masih
belum
banyak
dibahas.
Penelitian
ini
bertujuan
mengetahui
pengaruh
intermittent
terhadap
penurunan
HbA1c
tipe
2
Metode
penelitian
menggunakan
pendekatan
literature
review
dengan
memilih
artikel
dipublikasikan
antara
tahun
2018
hingga
2024.
Penelusuran
literatur
dilakukan
database
MEDLINE,
CENTRAL,
ProQuest,
serta
hand
search
referensi
terkait.
Kriteria
inklusi
melibatkan
studi
menerapkan
fasting.
Artikel
tidak
memenuhi
kriteria,
seperti
subjek
hewan,
dikeluarkan
dari
analisis.
Didapatkan
23
tiga
ditelusuri.
Setelah
diseleksi
berdasarkan
kriteria
eklusi
diperolah
lima
ditambah
dua
search.
Tujuh
disertakan
analisis
utama.
Semua
menunjukkan
signifikan
puasa
menjalani
intervensi
menjadi
alternatif
pengobatan
nonfarmakologis
menurunkan
lebih
lanjut
diperlukan
melihat
dampak
jangka
panjang
kaitannya
penggunaan
insulin
pasien
durasi
lama.