From Mother–Fetus Dyad to Mother–Milk–Infant Triad: Sex Differences in Macronutrient Composition of Breast Milk DOI Open Access
Maria Lithoxopoulou, Calliope Karastogiannidou,

Anastasia Karagkiozi

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(9), P. 1422 - 1422

Published: April 23, 2025

Background: The composition of breast milk is influenced by a variety factors, including maternal anthropometric characteristics, dietary and lifestyle habits, lactation feeding parameters. Emerging evidence also suggests that an infant’s sex may play role in shaping composition. Objective: This study aims to investigate the macronutrient early up 3 months postpartum, with particular focus on potential differences related sex. Methods: A total 102 samples were collected at four time points across three stages, representing colostrum, transitional, mature milk, from cohort consisting 51 consenting mothers Mediterranean origin who met inclusion criteria. analyzed using mid-infrared spectroscopy determine their Results: Colostrum male infants contained approximately 60% higher levels nitrogenous compounds, crude protein, true non-protein nitrogen compared colostrum female infants. Transitional for fat, solids, energy. No significant observed between sexes. For both sexes, more compounds fewer solids than milk. Male had lower carbohydrate later stages lactation, while showed no changes. Strong positive correlations fat protein found sexes during transitional stages. In all macronutrients interrelated. Conclusions: neonates suggest sex-specific nutritional adaptations lactation. These findings have implications personalized infant nutrition strategies cases where hampered, as well understanding neonatal adaptations.

Language: Английский

Breastfeeding Longitudinal Observational Study of Mothers and Kids—BLOSOM Cohort DOI Creative Commons
Zoya Gridneva, Ali S. Cheema,

Erika M. van den Dries

et al.

Published: Jan. 2, 2025

The Breastfeeding Longitudinal Observational Study of Mothers and kids (BLOSOM) is a single-centre prospective cohort study conducted in Perth (Western Australia) that collected data from 2018 to 2020 aimed investigate the mechanisms by which human milk affects infant growth, health, body composition [...]

Language: Английский

Citations

0
Bioactive compounds in human milk DOI
Anthony E. Castro, Maria Sanchez-Holgado, Miguel Sáenz de Pipaón

et al.

Current Opinion in Clinical Nutrition & Metabolic Care, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 12, 2025

Purpose of review: Human milk is the optimal food choice for infants. Reviewing latest advances in research about human compounds and their effect on health helps understand benefits breastfeeding improves knowledge key bioactive nutrients that can be used to improve feeding during infancy, with short long-time effects health. Recent findings: In last years, it has been described how such as oligosaccharides, hormones, lipids, cellular components microbes play an important role infants’ health, reducing risk infectious, metabolic autoimmune diseases. The mechanisms transmission from mother infant these are not always well described, but there several lines biological beneficial effects. Summary: These findings may help maternal interventions, modifiable factors able modulate composition. They development formulas enhance nutritional plans. Also, identification isolation describe new ways supplementation.

Language: Английский

Citations

0
From Mother–Fetus Dyad to Mother–Milk–Infant Triad: Sex Differences in Macronutrient Composition of Breast Milk DOI Open Access
Maria Lithoxopoulou, Calliope Karastogiannidou,

Anastasia Karagkiozi

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(9), P. 1422 - 1422

Published: April 23, 2025

Background: The composition of breast milk is influenced by a variety factors, including maternal anthropometric characteristics, dietary and lifestyle habits, lactation feeding parameters. Emerging evidence also suggests that an infant’s sex may play role in shaping composition. Objective: This study aims to investigate the macronutrient early up 3 months postpartum, with particular focus on potential differences related sex. Methods: A total 102 samples were collected at four time points across three stages, representing colostrum, transitional, mature milk, from cohort consisting 51 consenting mothers Mediterranean origin who met inclusion criteria. analyzed using mid-infrared spectroscopy determine their Results: Colostrum male infants contained approximately 60% higher levels nitrogenous compounds, crude protein, true non-protein nitrogen compared colostrum female infants. Transitional for fat, solids, energy. No significant observed between sexes. For both sexes, more compounds fewer solids than milk. Male had lower carbohydrate later stages lactation, while showed no changes. Strong positive correlations fat protein found sexes during transitional stages. In all macronutrients interrelated. Conclusions: neonates suggest sex-specific nutritional adaptations lactation. These findings have implications personalized infant nutrition strategies cases where hampered, as well understanding neonatal adaptations.

Language: Английский

Citations

0