Lactoferrin: Properties and Potential Uses in the Food Industry
International Journal of Molecular Sciences,
Journal Year:
2025,
Volume and Issue:
26(4), P. 1404 - 1404
Published: Feb. 7, 2025
Lactoferrin
(LF)
is
an
80
kDa
glycoprotein
that
contains
approximately
700
amino
acids
and
a
member
of
the
transferrin
family.
The
essential
properties
LF,
including
antimicrobial,
antiviral,
anticancer,
anti-inflammatory,
antioxidant,
probiotic
effects,
have
been
studied
for
decades.
iron
chelation
activity
LF
significantly
associated
with
its
antioxidant
properties.
Owing
to
prebiotic
activity,
also
facilitates
growth
beneficial
microorganisms
iron-defense
immediate-effect
on
pathogens.
Additionally,
ability
regulate
cell
signaling
pathways
immune
responses
makes
prominent
modulatory
protein.
These
diverse
characteristics
gained
interest
in
therapeutic
potential.
Studies
suggested
could
serve
as
alternative
source
antibiotics
severe
infections
illnesses.
has
food
industry
potential
additive
fortify
products
such
yogurt,
infant
formula,
meat
derivatives
while
improving
shelf
life
foods
providing
antimicrobial
activity.
Prior
using
industry,
safety
toxicity
processing
are
necessary
be
investigated.
investigations
crucial
addressing
harm
or
side
effects
ensuring
healthy
lifestyle.
This
review
discusses
attributes
particularly
exploitation
industry.
Language: Английский
Lactoferrin in cancer: Focus on mechanisms and translational medicine
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer,
Journal Year:
2025,
Volume and Issue:
unknown, P. 189330 - 189330
Published: April 1, 2025
Language: Английский
Bovine Colostrum in Pediatric Nutrition and Health
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(24), P. 4305 - 4305
Published: Dec. 13, 2024
Bovine
colostrum
(BC),
the
first
milk
secreted
by
mammals
after
birth,
is
a
trending
alternative
source
for
supplementing
infants
and
children,
offering
benefits
gut
immune
health.
Its
rich
components,
such
as
proteins,
immunoglobulins,
lactoferrin,
glycans,
are
used
to
fortify
diets
support
development.
Preterm
development
crucial,
especially
in
maturation
of
essential
systems,
from
2010
2020,
approximately
15%
all
premature
births
occurred
at
less
than
32
weeks
gestation
worldwide.
This
review
explores
composition,
benefits,
effects
BC
on
general
along
with
preterm
who
require
special
care,
highlights
its
role
growth
also
associated
specific
pediatric
diseases,
including
necrotizing
enterocolitis
(NEC),
infectious
diarrhea,
inflammatory
bowel
disease
(IBD),
short-bowel
syndrome
(SBS),
neonatal
sepsis,
gastrointestinal
respiratory
infections,
some
minor
conditions.
discusses
clinical
trials
regarding
these
conditions
which
occasionally
encountered
infants.
The
anti-inflammatory,
antimicrobial,
immunomodulatory,
antiviral
properties
discussed,
emphasizing
mechanisms
action.
Clinical
trials,
particularly
humans,
provide
evidence
supporting
inclusion
formulas
diets,
although
precise
standards
age,
feeding
time,
amounts
needed
ensure
safety
efficacy.
However,
potential
adverse
effects,
allergic
reactions
caseins
immunoglobulin
E,
must
be
considered.
More
comprehensive
necessary
expand
infant
feeding,
important
components
BC,
should
further
studied
their
synergistic
diseases.
Ultimately,
shows
promise
health
incorporated
into
nutritional
supplements
caution.
Language: Английский
Lactoferrin as a Versatile Agent in Nanoparticle Applications: From Therapeutics to Agriculture
Nanomaterials,
Journal Year:
2024,
Volume and Issue:
14(24), P. 2018 - 2018
Published: Dec. 16, 2024
Nanoparticles
(NPs)
have
emerged
as
a
potent
choice
for
various
applications,
from
drug
delivery
to
agricultural
studies,
serving
an
alternative
and
promising
methodology
future
advancements.
They
been
widely
explored
in
systems,
demonstrating
immense
promise
high
efficiency
the
of
numerous
biomolecules
such
proteins
anticancer
agents,
either
solely
or
modified
with
other
compounds
enhance
their
capabilities.
In
addition,
utilization
NPs
extends
antimicrobial
where
they
are
used
develop
novel
antibacterial,
antifungal,
antiviral
formulations
advanced
characteristics.
Lactoferrin
(Lf)
is
glycoprotein
recognized
its
significant
multifunctional
properties,
antimicrobial,
antioxidant,
anti-inflammatory,
anticancer,
neuroprotective
effects.
Its
activity
has
broad
distribution
human
body,
Lf
receptors
present
multiple
regions.
Current
research
shows
that
utilized
NP
technology
surface
material,
encapsulated
biomolecule,
even
itself.
Due
abundance
regions,
can
be
employed
material
targeted
strategies,
particularly
crossing
BBB
targeting
specific
cancers.
Furthermore,
synthesized
structure,
positioning
it
strong
candidate
NP-related
applications.
this
article,
we
explore
highlighted
underexplored
areas
applications
research.
Language: Английский