Neurofeedback for Anorexia — RelaxNeuron — Aimed in Dissolving the Root Neuronal Cause DOI Creative Commons
Kana Matsuyanagi

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: March 18, 2025

Abstract Anorexia Nervosa (AN) is a complex disorder involving psychological, neurobiological, and metabolic dysregulation, characterized by an intense fear of weight gain severe food restriction. Despite the availability outpatient psychotherapies, current treatment approaches face significant barriers, including high costs, limited accessibility, relapse rates. Additionally, traditional interventions often rely on verbal engagement cognitive restructuring, which may be ineffective for individuals with rigidity impaired interoception—key features AN. These challenges underscore urgent need accessible, self-administered intervention that can complement existing therapies. To address this need, we developed RelaxNeuron, novel neurofeedback (NF) software designed to modulate response stimuli facilitate adaptive neural regulation in AN patient. Unlike conventional NF, targets general states, RelaxNeuron dynamically responds users' emotional physiological reactions using electroencephalography (EEG) electrocardiogram (ECG) signals. The system provides real-time feedback based both state inference eye-tracking performance, helping users gradually reduce food-related anxiety attentional biases. By reinforcing more patterns through repeated training, aims alleviate conditioned responses, promoting flexible less distressing food. Beyond its therapeutic application, also serves as research instrument studying neurophysiological aspects AN, particularly eye movement abnormalities, interoceptive deficits, modulation. Given multifactorial nature future studies should explore integrating genetic-based optimize long-term recovery outcomes. Preliminary results suggest NF-based offer promising, cost-effective, scalable alternative struggling those unable access treatment. Further needed validate clinical efficacy integration within comprehensive, multidisciplinary framework.

Language: Английский

Neurofeedback for Anorexia — RelaxNeuron — Aimed in Dissolving the Root Neuronal Cause DOI Creative Commons
Kana Matsuyanagi

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: March 18, 2025

Abstract Anorexia Nervosa (AN) is a complex disorder involving psychological, neurobiological, and metabolic dysregulation, characterized by an intense fear of weight gain severe food restriction. Despite the availability outpatient psychotherapies, current treatment approaches face significant barriers, including high costs, limited accessibility, relapse rates. Additionally, traditional interventions often rely on verbal engagement cognitive restructuring, which may be ineffective for individuals with rigidity impaired interoception—key features AN. These challenges underscore urgent need accessible, self-administered intervention that can complement existing therapies. To address this need, we developed RelaxNeuron, novel neurofeedback (NF) software designed to modulate response stimuli facilitate adaptive neural regulation in AN patient. Unlike conventional NF, targets general states, RelaxNeuron dynamically responds users' emotional physiological reactions using electroencephalography (EEG) electrocardiogram (ECG) signals. The system provides real-time feedback based both state inference eye-tracking performance, helping users gradually reduce food-related anxiety attentional biases. By reinforcing more patterns through repeated training, aims alleviate conditioned responses, promoting flexible less distressing food. Beyond its therapeutic application, also serves as research instrument studying neurophysiological aspects AN, particularly eye movement abnormalities, interoceptive deficits, modulation. Given multifactorial nature future studies should explore integrating genetic-based optimize long-term recovery outcomes. Preliminary results suggest NF-based offer promising, cost-effective, scalable alternative struggling those unable access treatment. Further needed validate clinical efficacy integration within comprehensive, multidisciplinary framework.

Language: Английский

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